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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Jurkat Cells are shown below. Double-click or tap a node for more information.
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- NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP.
Sun C, Cai M, Gunasekera AH, Meadows RP, Wang H, Chen J, Zhang H, Wu W, Xu N, Ng SC, Fesik SW
(1999) Nature 401: 818-22 - A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.
Westphal RS, Anderson KA, Means AR, Wadzinski BE
(1998) Science 280: 1258-61 - Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.
Perry JSA, Morioka S, Medina CB, Iker Etchegaray J, Barron B, Raymond MH, Lucas CD, Onengut-Gumuscu S, Delpire E, Ravichandran KS
(2019) Nat Cell Biol 21: 1532-1543 - Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE
(2018) Immunity 49: 363-374.e10 - MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE
(2018) Mol Cell 70: 936-948.e7 - Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling.
Medeiros AI, Serezani CH, Lee SP, Peters-Golden M
(2009) J Exp Med 206: 61-8 - Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion.
Sundrud MS, Torres VJ, Unutmaz D, Cover TL
(2004) Proc Natl Acad Sci U S A 101: 7727-32 - Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.
Zeng C, van Wijnen AJ, Stein JL, Meyers S, Sun W, Shopland L, Lawrence JB, Penman S, Lian JB, Stein GS, Hiebert SW
(1997) Proc Natl Acad Sci U S A 94: 6746-51 - Preparation of functionally active cell-permeable peptides by single-step ligation of two peptide modules.
Zhang L, Torgerson TR, Liu XY, Timmons S, Colosia AD, Hawiger J, Tam JP
(1998) Proc Natl Acad Sci U S A 95: 9184-9 - T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-site.
Tong Y, Aune T, Boothby M
(2005) Proc Natl Acad Sci U S A 102: 2034-9 - Mechanisms of apoptosis in T cells from patients with renal cell carcinoma.
Uzzo RG, Rayman P, Kolenko V, Clark PE, Bloom T, Ward AM, Molto L, Tannenbaum C, Worford LJ, Bukowski R, Tubbs R, Hsi ED, Bander NH, Novick AC, Finke JH
(1999) Clin Cancer Res 5: 1219-29 - RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.
Reed-Inderbitzin E, Moreno-Miralles I, Vanden-Eynden SK, Xie J, Lutterbach B, Durst-Goodwin KL, Luce KS, Irvin BJ, Cleary ML, Brandt SJ, Hiebert SW
(2006) Oncogene 25: 5777-86 - Opposing roles for RelB and Bcl-3 in regulation of T-box expressed in T cells, GATA-3, and Th effector differentiation.
Corn RA, Hunter C, Liou HC, Siebenlist U, Boothby MR
(2005) J Immunol 175: 2102-10 - New programming of IL-4 receptor signal transduction in activated T cells: Stat6 induction and Th2 differentiation mediated by IL-4Ralpha lacking cytoplasmic tyrosines.
Mora AL, Stephenson LM, Enerson B, Youn J, Keegan AD, Boothby M
(2003) J Immunol 171: 1891-900 - Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50.
Torgerson TR, Colosia AD, Donahue JP, Lin YZ, Hawiger J
(1998) J Immunol 161: 6084-92 - ZAP-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis.
Eischen CM, Williams BL, Zhang W, Samelson LE, Lynch DH, Abraham RT, Leibson PJ
(1997) J Immunol 159: 1135-9 - Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kappaB in FGF receptor-bearing Jurkat T cells.
Byrd VM, Ballard DW, Miller GG, Thomas JW
(1999) J Immunol 162: 5853-9 - A minimal IFN-gamma promoter confers Th1 selective expression.
Soutto M, Zhang F, Enerson B, Tong Y, Boothby M, Aune TM
(2002) J Immunol 169: 4205-12 - Cutting edge: distal regulatory elements are required to achieve selective expression of IFN-gamma in Th1/Tc1 effector cells.
Soutto M, Zhou W, Aune TM
(2002) J Immunol 169: 6664-7 - LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.
Layer JH, Alford CE, McDonald WH, Davé UP
(2016) Mol Cell Biol 36: 488-506 - B-Raf-mediated signaling pathway regulates T cell development.
Tsukamoto H, Irie A, Senju S, Hatzopoulos AK, Wojnowski L, Nishimura Y
(2008) Eur J Immunol 38: 518-27 - Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
Kray AE, Carter RS, Pennington KN, Gomez RJ, Sanders LE, Llanes JM, Khan WN, Ballard DW, Wadzinski BE
(2005) J Biol Chem 280: 35974-82 - The tax oncoprotein of human T-cell leukemia virus type 1 associates with and persistently activates IkappaB kinases containing IKKalpha and IKKbeta.
Chu ZL, DiDonato JA, Hawiger J, Ballard DW
(1998) J Biol Chem 273: 15891-4 - A functional fibroblast growth factor-1 immunoglobulin fusion protein.
Dikov MM, Reich MB, Dworkin L, Thomas JW, Miller GG
(1998) J Biol Chem 273: 15811-7 - RACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.
Chen S, Lin F, Shin ME, Wang F, Shen L, Hamm HE
(2008) Mol Biol Cell 19: 3909-22 - Methotrexate induces production of IL-1 and IL-6 in the monocytic cell line U937.
Olsen NJ, Spurlock CF, Aune TM
(2014) Arthritis Res Ther 16: R17 - Methotrexate-mediated inhibition of nuclear factor κB activation by distinct pathways in T cells and fibroblast-like synoviocytes.
Spurlock CF, Gass HM, Bryant CJ, Wells BC, Olsen NJ, Aune TM
(2015) Rheumatology (Oxford) 54: 178-87 - Immunomodulatory metabolites released by the frog-killing fungus Batrachochytrium dendrobatidis.
Rollins-Smith LA, Fites JS, Reinert LK, Shiakolas AR, Umile TP, Minbiole KP
(2015) Infect Immun 83: 4565-70 - Resistance of primary murine CD4+ T cells to Helicobacter pylori vacuolating cytotoxin.
Algood HM, Torres VJ, Unutmaz D, Cover TL
(2007) Infect Immun 75: 334-41 - The intermediate region of Helicobacter pylori VacA is a determinant of toxin potency in a Jurkat T cell assay.
González-Rivera C, Algood HM, Radin JN, McClain MS, Cover TL
(2012) Infect Immun 80: 2578-88 - Fibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway.
Byrd VM, Kilkenny DM, Dikov MM, Reich MB, Rocheleau JV, Armistead WJ, Thomas JW, Miller GG
(2003) Immunol Cell Biol 81: 440-50 - Identification of a type 6 protein ser/thr phosphatase regulated by interleukin-2 stimulation.
Filali M, Li S, Kim HW, Wadzinski B, Kamoun M
(1999) J Cell Biochem 73: 153-63 - Innate immunity and inflammation: a transcriptional paradigm.
Hawiger J
(2001) Immunol Res 23: 99-109 - The microfluidic multitrap nanophysiometer for hematologic cancer cell characterization reveals temporal sensitivity of the calcein-AM efflux assay.
Byrd TF, Hoang LT, Kim EG, Pfister ME, Werner EM, Arndt SE, Chamberlain JW, Hughey JJ, Nguyen BA, Schneibel EJ, Wertz LL, Whitfield JS, Wikswo JP, Seale KT
(2014) Sci Rep 4: 5117 - Molecular imaging of human tumor cells that naturally overexpress type 2 cannabinoid receptors using a quinolone-based near-infrared fluorescent probe.
Wu Z, Shao P, Zhang S, Ling X, Bai M
(2014) J Biomed Opt 19: 76016 - Efferocytosis-induced prostaglandin E2 production impairs alveolar macrophage effector functions during Streptococcus pneumoniae infection.
Salina AC, Souza TP, Serezani CH, Medeiros AI
(2017) Innate Immun 23: 219-227 - Differential serine phosphorylation regulates IkappaB-alpha inactivation.
Chen CL, Yull FE, Kerr LD
(1999) Biochem Biophys Res Commun 257: 798-806 - Single cell analysis of human tissues and solid tumors with mass cytometry.
Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffmann RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, Ihrie RA, Irish JM
(2017) Cytometry B Clin Cytom 92: 68-78 - Towards monitoring real-time cellular response using an integrated microfluidics-matrix assisted laser desorption ionisation/nanoelectrospray ionisation-ion mobility-mass spectrometry platform.
Enders JR, Marasco CC, Kole A, Nguyen B, Sevugarajan S, Seale KT, Wikswo JP, McLean JA
(2010) IET Syst Biol 4: 416-27 - Quantum dot probes for monitoring dynamic cellular response: reporters of T cell activation.
Warnement MR, Faley SL, Wikswo JP, Rosenthal SJ
(2006) IEEE Trans Nanobioscience 5: 268-72
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