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•  John Oates

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Publications

• Efficacy and safety of recombinant human activated protein C for severe sepsis.
  Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ, Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group
  (2001) N Engl J Med 344: 699-709
• Factor XI antisense oligonucleotide for prevention of venous thrombosis.
  Büller HR, Bethune C, Bhanot S, Gailani D, Monia BP, Raskob GE, Segers A, Verhamme P, Weitz JI, FXI-ASO TKA Investigators
  (2015) N Engl J Med 372: 232-40
• The index case for the fungal meningitis outbreak in the United States.
  Pettit AC, Kropski JA, Castilho JL, Schmitz JE, Rauch CA, Mobley BC, Wang XJ, Spires SS, Pugh ME
  (2012) N Engl J Med 367: 2119-25
• Syk tyrosine kinase required for mouse viability and B-cell development.
  Cheng AM, Rowley B, Pao W, Hayday A, Bolen JB, Pawson T
  (1995) Nature 378: 303-6
• Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection.
  Flyak AI, Shen X, Murin CD, Turner HL, David JA, Fusco ML, Lampley R, Kose N, Ilinykh PA, Kuzmina N, Branchizio A, King H, Brown L, Bryan C, Davidson E, Doranz BJ, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Saphire EO, Ward AB, Bukreyev A, Crowe JE
  (2016) Cell 164: 392-405
• A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses.
  Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, Bharrhan S, Kuehne AI, Bornholdt ZA, Flyak AI, Saphire EO, Crowe JE, Aman MJ, Dye JM, Lai JR, Chandran K
  (2016) Science 354: 350-354
• Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus.
  Karimy JK, Zhang J, Kurland DB, Theriault BC, Duran D, Stokum JA, Furey CG, Zhou X, Mansuri MS, Montejo J, Vera A, DiLuna ML, Delpire E, Alper SL, Gunel M, Gerzanich V, Medzhitov R, Simard JM, Kahle KT
  (2017) Nat Med 23: 997-1003
• Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
  Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE
  (2020) Immunity 52: 388-403.e12
• Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
  Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE
  (2018) Immunity 49: 363-374.e10
• Berlin Heart EXCOR pediatric ventricular assist device for bridge to heart transplantation in US children.
  Almond CS, Morales DL, Blackstone EH, Turrentine MW, Imamura M, Massicotte MP, Jordan LC, Devaney EJ, Ravishankar C, Kanter KR, Holman W, Kroslowitz R, Tjossem C, Thuita L, Cohen GA, Buchholz H, St Louis JD, Nguyen K, Niebler RA, Walters HL, Reemtsen B, Wearden PD, Reinhartz O, Guleserian KJ, Mitchell MB, Bleiweis MS, Canter CE, Humpl T
  (2013) Circulation 127: 1702-11
• Outcomes with concurrent use of clopidogrel and proton-pump inhibitors: a cohort study.
  Ray WA, Murray KT, Griffin MR, Chung CP, Smalley WE, Hall K, Daugherty JR, Kaltenbach LA, Stein CM
  (2010) Ann Intern Med 152: 337-45
• Nonsteroidal anti-inflammatory drug use and death from peptic ulcer in elderly persons.
  Griffin MR, Ray WA, Schaffner W
  (1988) Ann Intern Med 109: 359-63
• Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Prevalence and clinical significance.
  Love PE, Santoro SA
  (1990) Ann Intern Med 112: 682-98
• Defective thrombus formation in mice lacking coagulation factor XII.
  Renné T, Pozgajová M, Grüner S, Schuh K, Pauer HU, Burfeind P, Gailani D, Nieswandt B
  (2005) J Exp Med 202: 271-81
• Elimination of Helicobacter pylori or acid in high-risk users of aspirin or nonsteroidal medications: final answer?
  Peek RM
  (2002) Gastroenterology 122: 238-40
• p120-Catenin is required for mouse vascular development.
  Oas RG, Xiao K, Summers S, Wittich KB, Chiasson CM, Martin WD, Grossniklaus HE, Vincent PA, Reynolds AB, Kowalczyk AP
  (2010) Circ Res 106: 941-51
• Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery.
  Yum LK, Byndloss MX, Feldman SH, Agaisse H
  (2019) Nat Commun 10: 1826
• Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.
  Revenko AS, Gao D, Crosby JR, Bhattacharjee G, Zhao C, May C, Gailani D, Monia BP, MacLeod AR
  (2011) Blood 118: 5302-11
• Identification of mutations and polymorphisms in the factor XI genes of an African American family by dideoxyfingerprinting.
  Martincic D, Zimmerman SA, Ware RE, Sun MF, Whitlock JA, Gailani D
  (1998) Blood 92: 3309-17
• A hereditary bleeding disorder of dogs caused by a lack of platelet procoagulant activity.
  Brooks MB, Catalfamo JL, Brown HA, Ivanova P, Lovaglio J
  (2002) Blood 99: 2434-41
• A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.
  Navarrete AM, Casari C, Legendre P, Marx I, Hu JR, Lenting PJ, Christophe OD, Denis CV
  (2012) Blood 120: 2723-32
• Platelet surface collagen receptor polymorphisms: variable receptor expression and thrombotic/hemorrhagic risk.
  Santoro SA
  (1999) Blood 93: 3575-7
• Central nervous system complications and management in sickle cell disease.
  DeBaun MR, Kirkham FJ
  (2016) Blood 127: 829-38
• Inhibitory Anti-Peroxidasin Antibodies in Pulmonary-Renal Syndromes.
  McCall AS, Bhave G, Pedchenko V, Hess J, Free M, Little DJ, Baker TP, Pendergraft WF, Falk RJ, Olson SW, Hudson BG
  (2018) J Am Soc Nephrol 29: 2619-2625
• Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress.
  Bastarache JA, Sebag SC, Clune JK, Grove BS, Lawson WE, Janz DR, Roberts LJ, Dworski R, Mackman N, Ware LB
  (2012) Thorax 67: 1032-9
• Deaths from stroke in US children, 1979 to 1998.
  Fullerton HJ, Chetkovich DM, Wu YW, Smith WS, Johnston SC
  (2002) Neurology 59: 34-9
• Studies of gastric ulcer disease by community-based gastroenterologists.
  Brazer SR, Tyor MP, Pancotto FS, Nickl NJ, Wildermann NM, Harrell FE, Pryor DB
  (1990) Am J Gastroenterol 85: 824-8
• Are isofurans and neuroprostanes increased after subarachnoid hemorrhage and traumatic brain injury?
  Corcoran TB, Mas E, Barden AE, Durand T, Galano JM, Roberts LJ, Phillips M, Ho KM, Mori TA
  (2011) Antioxid Redox Signal 15: 2663-7
• Contribution of endogenous bradykinin to fibrinolysis, inflammation, and blood product transfusion following cardiac surgery: a randomized clinical trial.
  Balaguer JM, Yu C, Byrne JG, Ball SK, Petracek MR, Brown NJ, Pretorius M
  (2013) Clin Pharmacol Ther 93: 326-34
• Factor XI as a target for antithrombotic therapy.
  Bane CE, Gailani D
  (2014) Drug Discov Today 19: 1454-8
• Haemosiderin-laden macrophages in the bronchoalveolar lavage fluid of patients with diffuse alveolar damage.
  Maldonado F, Parambil JG, Yi ES, Decker PA, Ryu JH
  (2009) Eur Respir J 33: 1361-6
• Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates.
  Crosby JR, Marzec U, Revenko AS, Zhao C, Gao D, Matafonov A, Gailani D, MacLeod AR, Tucker EI, Gruber A, Hanson SR, Monia BP
  (2013) Arterioscler Thromb Vasc Biol 33: 1670-8
• Interaction of platelet activating factor, reactive oxygen species generated by xanthine oxidase, and leukocytes in the generation of hepatic injury after shock/resuscitation.
  Yamakawa Y, Takano M, Patel M, Tien N, Takada T, Bulkley GB
  (2000) Ann Surg 231: 387-98
• The importance of cerebral aneurysms in childhood hemorrhagic stroke: a population-based study.
  Jordan LC, Johnston SC, Wu YW, Sidney S, Fullerton HJ
  (2009) Stroke 40: 400-5
• Pediatric intracerebral hemorrhage score: a simple grading scale for intracerebral hemorrhage in children.
  Beslow LA, Ichord RN, Gindville MC, Kleinman JT, Engelmann K, Bastian RA, Licht DJ, Smith SE, Hillis AE, Jordan LC
  (2014) Stroke 45: 66-70
• Predictors of outcome in childhood intracerebral hemorrhage: a prospective consecutive cohort study.
  Beslow LA, Licht DJ, Smith SE, Storm PB, Heuer GG, Zimmerman RA, Feiler AM, Kasner SE, Ichord RN, Jordan LC
  (2010) Stroke 41: 313-8
• ABC/XYZ estimates intracerebral hemorrhage volume as a percent of total brain volume in children.
  Beslow LA, Ichord RN, Kasner SE, Mullen MT, Licht DJ, Smith SE, Storm PB, Jordan LC, Messé SR
  (2010) Stroke 41: 691-4
• Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage: A Prospective Study.
  Porcari GS, Beslow LA, Ichord RN, Licht DJ, Kleinman JT, Jordan LC
  (2018) Stroke 49: 1755-1758
• Intracerebral hemorrhage volume predicts poor neurologic outcome in children.
  Jordan LC, Kleinman JT, Hillis AE
  (2009) Stroke 40: 1666-71