Keyword Connections

•  Amanda Peltier
•  Bruce Damon
•  Christopher Elder
•  Daniel Lark

•  David Wasserman
•  Deborah Murdock
•  Jorge Gamboa
•  Kristin Swygert

•  Louise Lantier
•  Padmini Komalavilas

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Communities

• Metabolism Interest Group

Publications

• A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use.
  Liu S, Brown JD, Stanya KJ, Homan E, Leidl M, Inouye K, Bhargava P, Gangl MR, Dai L, Hatano B, Hotamisligil GS, Saghatelian A, Plutzky J, Lee CH
  (2013) Nature 502: 550-4
• C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons.
  Miller DM, Shen MM, Shamu CE, Bürglin TR, Ruvkun G, Dubois ML, Ghee M, Wilson L
  (1992) Nature 355: 841-5
• Disruption of IRS-2 causes type 2 diabetes in mice.
  Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, White MF
  (1998) Nature 391: 900-4
• Mox2 is a component of the genetic hierarchy controlling limb muscle development.
  Mankoo BS, Collins NS, Ashby P, Grigorieva E, Pevny LH, Candia A, Wright CV, Rigby PW, Pachnis V
  (1999) Nature 400: 69-73
• Dynamic landscape and regulation of RNA editing in mammals.
  Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, Liu KI, Zhang R, Ramaswami G, Ariyoshi K, Gupte A, Keegan LP, George CX, Ramu A, Huang N, Pollina EA, Leeman DS, Rustighi A, Goh YPS, GTEx Consortium, Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group, Statistical Methods groups—Analysis Working Group, Enhancing GTEx (eGTEx) groups, NIH Common Fund, NIH/NCI, NIH/NHGRI, NIH/NIMH, NIH/NIDA, Biospecimen Collection Source Site—NDRI, Biospecimen Collection Source Site—RPCI, Biospecimen Core Resource—VARI, Brain Bank Repository—University of Miami Brain Endowment Bank, Leidos Biomedical—Project Management, ELSI Study, Genome Browser Data Integration &Visualization—EBI, Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Chawla A, Del Sal G, Peltz G, Brunet A, Conrad DF, Samuel CE, O'Connell MA, Walkley CR, Nishikura K, Li JB
  (2017) Nature 550: 249-254
• Protein kinase C phosphorylates pp60src at a novel site.
  Gould KL, Woodgett JR, Cooper JA, Buss JE, Shalloway D, Hunter T
  (1985) Cell 42: 849-57
• Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.
  Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, Hinoue T, Laird PW, Hoadley KA, Akbani R, Castro MAA, Gibb EA, Kanchi RS, Gordenin DA, Shukla SA, Sanchez-Vega F, Hansel DE, Czerniak BA, Reuter VE, Su X, de Sa Carvalho B, Chagas VS, Mungall KL, Sadeghi S, Pedamallu CS, Lu Y, Klimczak LJ, Zhang J, Choo C, Ojesina AI, Bullman S, Leraas KM, Lichtenberg TM, Wu CJ, Schultz N, Getz G, Meyerson M, Mills GB, McConkey DJ, TCGA Research Network, Weinstein JN, Kwiatkowski DJ, Lerner SP
  (2017) Cell 171: 540-556.e25
• Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier.
  Arima Y, Harada M, Kamimura D, Park JH, Kawano F, Yull FE, Kawamoto T, Iwakura Y, Betz UA, Márquez G, Blackwell TS, Ohira Y, Hirano T, Murakami M
  (2012) Cell 148: 447-57
• Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
  Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA
  (2013) Cell 155: 1624-38
• Trefoil peptides: less clandestine in the intestine.
  Chinery R, Coffey RJ
  (1996) Science 274: 204
• Myoblast therapy.
  Epstein HF, Fischman DA, Bader D, Changeux JP, Buckhold K, Ordahl CP, Hoffman E, Kedes LH, Konieczny S, Leinwand LA
  (1992) Science 257: 738
• Teratogen-mediated inhibition of target tissue response to Shh signaling.
  Cooper MK, Porter JA, Young KE, Beachy PA
  (1998) Science 280: 1603-7
• Coronary arterial smooth muscle contraction by a substance released from platelets: evidence that it is thromboxane A2.
  Ellis EF, Oelz O, Roberts LJ, Payne NA, Sweetman BJ, Nies AS, Oates JA
  (1976) Science 193: 1135-7
• Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.
  Uno K, Katagiri H, Yamada T, Ishigaki Y, Ogihara T, Imai J, Hasegawa Y, Gao J, Kaneko K, Iwasaki H, Ishihara H, Sasano H, Inukai K, Mizuguchi H, Asano T, Shiota M, Nakazato M, Oka Y
  (2006) Science 312: 1656-9
• Concerning the validity of gastrointestinal extracellular recordings.
  O'Grady G, Angeli T, Du P, Cheng LK
  (2015) Physiol Rev 95: 691-2
• Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.
  Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW
  (2016) Nat Med 22: 800-6
• Aberrant cannabinoid signaling impairs oviductal transport of embryos.
  Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK, DuBois RN, Dey SK
  (2004) Nat Med 10: 1074-80
• Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.
  An J, Muoio DM, Shiota M, Fujimoto Y, Cline GW, Shulman GI, Koves TR, Stevens R, Millington D, Newgard CB
  (2004) Nat Med 10: 268-74
• Loss of SM-B myosin affects muscle shortening velocity and maximal force development.
  Babu GJ, Loukianov E, Loukianova T, Pyne GJ, Huke S, Osol G, Low RB, Paul RJ, Periasamy M
  (2001) Nat Cell Biol 3: 1025-9
• A primary culture system for functional analysis of C. elegans neurons and muscle cells.
  Christensen M, Estevez A, Yin X, Fox R, Morrison R, McDonnell M, Gleason C, Miller DM, Strange K
  (2002) Neuron 33: 503-14
• Adenosine increases sympathetic nerve traffic in humans.
  Biaggioni I, Killian TJ, Mosqueda-Garcia R, Robertson RM, Robertson D
  (1991) Circulation 83: 1668-75
• Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.
  Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR, METASTROKE Consortium, AFGen Consortium, Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT
  (2014) Circulation 130: 1225-35
• Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction.
  Jain M, DerSimonian H, Brenner DA, Ngoy S, Teller P, Edge AS, Zawadzka A, Wetzel K, Sawyer DB, Colucci WS, Apstein CS, Liao R
  (2001) Circulation 103: 1920-7
• Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma.
  Khatri JJ, Johnson C, Magid R, Lessner SM, Laude KM, Dikalov SI, Harrison DG, Sung HJ, Rong Y, Galis ZS
  (2004) Circulation 109: 520-5
• Mechanisms of interaction between the sulfhydryl precursor L-methionine and glyceryl trinitrate.
  Münzel T, Mülsch A, Holtz J, Just H, Harrison DG, Bassenge E
  (1992) Circulation 86: 995-1003
• Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs.
  Gumina RJ, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ
  (1999) Circulation 100: 2519-26; discussion 2469-72
• Evidence for inflammatory signaling in idiopathic pulmonary artery hypertension: TRPC6 and nuclear factor-kappaB.
  Hamid R, Newman JH
  (2009) Circulation 119: 2297-8
• Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice.
  Dikalova A, Clempus R, Lassègue B, Cheng G, McCoy J, Dikalov S, San Martin A, Lyle A, Weber DS, Weiss D, Taylor WR, Schmidt HH, Owens GK, Lambeth JD, Griendling KK
  (2005) Circulation 112: 2668-76
• Blockade of nucleoside transport is required for delivery of intraarterial adenosine into the interstitium: relevance to therapeutic preconditioning in humans.
  Gamboa A, Ertl AC, Costa F, Farley G, Manier ML, Hachey DL, Diedrich A, Biaggioni I
  (2003) Circulation 108: 2631-5
• Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.
  Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, Troncoso JC, Albert MS, Thambisetty M
  (2017) Mol Psychiatry 22: 13-23
• SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.
  Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA
  (2012) Cell Metab 15: 675-90
• Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking.
  Chen S, Wasserman DH, MacKintosh C, Sakamoto K
  (2011) Cell Metab 13: 68-79
• Re: Microfibrillar structure of type I collagen in situ.
  Okuyama K, Bächinger HP, Mizuno K, Boudko S, Engel J, Berisio R, Vitagliano L
  (2009) Acta Crystallogr D Biol Crystallogr 65: 1007-8; author reply 1009-10
• Calcium-dependent NOX5 nicotinamide adenine dinucleotide phosphate oxidase contributes to vascular oxidative stress in human coronary artery disease.
  Guzik TJ, Chen W, Gongora MC, Guzik B, Lob HE, Mangalat D, Hoch N, Dikalov S, Rudzinski P, Kapelak B, Sadowski J, Harrison DG
  (2008) J Am Coll Cardiol 52: 1803-9
• Cellular and molecular pathobiology of pulmonary arterial hypertension.
  Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M
  (2004) J Am Coll Cardiol 43: 13S-24S
• Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial.
  Nass R, Pezzoli SS, Oliveri MC, Patrie JT, Harrell FE, Clasey JL, Heymsfield SB, Bach MA, Vance ML, Thorner MO
  (2008) Ann Intern Med 149: 601-11
• Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling.
  Rai V, Touré F, Chitayat S, Pei R, Song F, Li Q, Zhang J, Rosario R, Ramasamy R, Chazin WJ, Schmidt AM
  (2012) J Exp Med 209: 2339-50