Structural basis of ligand binding modes at the neuropeptide Y Y receptor. Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B (2018) Nature 556: 520-524 Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR (1994) Science 265: 1405-12 A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. Odom AR, Stahlberg A, Wente SR, York JD (2000) Science 287: 2026-9 Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Tao R, Coleman MC, Pennington JD, Ozden O, Park SH, Jiang H, Kim HS, Flynn CR, Hill S, Hayes McDonald W, Olivier AK, Spitz DR, Gius D (2010) Mol Cell 40: 893-904 Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, McGoon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, Tuder RM, Voelkel NF, Gail DB, National Heart, Lung and Blood Institute/Office of Rare Diseases (2004) Circulation 109: 2947-52 Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community. Böger RH, Sullivan LM, Schwedhelm E, Wang TJ, Maas R, Benjamin EJ, Schulze F, Xanthakis V, Benndorf RA, Vasan RS (2009) Circulation 119: 1592-600 Insulin signaling in alpha cells modulates glucagon secretion in vivo. Kawamori D, Kurpad AJ, Hu J, Liew CW, Shih JL, Ford EL, Herrera PL, Polonsky KS, McGuinness OP, Kulkarni RN (2009) Cell Metab 9: 350-61 Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. Desimone MC, Rathmell WK, Threadgill DW (2013) J Natl Cancer Inst 105: 1355-64 An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC. Pattanayek R, Xu Y, Lamichhane A, Johnson CH, Egli M (2014) Acta Crystallogr D Biol Crystallogr 70: 1375-90 Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production. Chaturvedi R, Asim M, Hoge S, Lewis ND, Singh K, Barry DP, de Sablet T, Piazuelo MB, Sarvaria AR, Cheng Y, Closs EI, Casero RA, Gobert AP, Wilson KT (2010) Gastroenterology 139: 1686-98, 1698.e1-6 Changes in pulmonary vascular tone during exercise. Effects of nitric oxide (NO) synthase inhibition, L-arginine infusion, and NO inhalation. Koizumi T, Gupta R, Banerjee M, Newman JH (1994) J Clin Invest 94: 2275-82 Exercise-induced pulmonary vasoconstriction during combined blockade of nitric oxide synthase and beta adrenergic receptors. Kane DW, Tesauro T, Koizumi T, Gupta R, Newman JH (1994) J Clin Invest 93: 677-83 Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta. Minor RL, Myers PR, Guerra R, Bates JN, Harrison DG (1990) J Clin Invest 86: 2109-16 Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ (2018) Proc Natl Acad Sci U S A 115: 9228-9233 Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: a strategy for bacterial survival. Gobert AP, McGee DJ, Akhtar M, Mendz GL, Newton JC, Cheng Y, Mobley HL, Wilson KT (2001) Proc Natl Acad Sci U S A 98: 13844-9 SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract. MacMillan AM, McCaw PS, Crispino JD, Sharp PA (1997) Proc Natl Acad Sci U S A 94: 133-6 No effect of clot age or thrombolysis on argatroban's inhibition of thrombin. Hantgan RR, Jerome WG, Hursting MJ (1998) Blood 92: 2064-74 ddAVP does not stimulate acute changes in levels of medullary trimethylamines in humans. Avison MJ, Van Why SK, Siegel NJ (1993) J Am Soc Nephrol 4: 1379-84 Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis. Ferrario R, Takahashi K, Fogo A, Badr KF, Munger KA (1994) J Am Soc Nephrol 4: 1847-54 GSK3beta mediates renal response to vasopressin by modulating adenylate cyclase activity. Rao R, Patel S, Hao C, Woodgett J, Harris R (2010) J Am Soc Nephrol 21: 428-37 Novobiocin precipitates histones at concentrations normally used to inhibit eukaryotic type II topoisomerase. Cotten M, Bresnahan D, Thompson S, Sealy L, Chalkley R (1986) Nucleic Acids Res 14: 3671-86 Dual role of arginine metabolism in establishing pathogenesis. Gogoi M, Datey A, Wilson KT, Chakravortty D (2016) Curr Opin Microbiol 29: 43-8 Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Cheng H, Wang H, Fan X, Paueksakon P, Harris RC (2012) Kidney Int 82: 1176-83 Effect of arginine on glucose turnover and plasma free fatty acids in normal dogs. Cherrington AD, Vranic M (1973) Diabetes 22: 537-43 Chronic treatment with sildenafil improves energy balance and insulin action in high fat-fed conscious mice. Ayala JE, Bracy DP, Julien BM, Rottman JN, Fueger PT, Wasserman DH (2007) Diabetes 56: 1025-33 Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase. Gunawardana SC, Rocheleau JV, Head WS, Piston DW (2006) Diabetes 55: 1029-33 Arginine infusion in dogs. Model for the roles of insulin and glucagon in regulating glucose turnover and free fatty acid levels. Cherrington AD, Kawamori R, Pek S, Vranic M (1974) Diabetes 23: 805-15 Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy. Pedchenko VK, Chetyrkin SV, Chuang P, Ham AJ, Saleem MA, Mathieson PW, Hudson BG, Voziyan PA (2005) Diabetes 54: 2952-60 Hypothalamic-pituitary-adrenal axis perturbations in patients with fibromyalgia. Crofford LJ, Pillemer SR, Kalogeras KT, Cash JM, Michelson D, Kling MA, Sternberg EM, Gold PW, Chrousos GP, Wilder RL (1994) Arthritis Rheum 37: 1583-92 Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis. Zhu S, Chen Z, Katsha A, Hong J, Belkhiri A, El-Rifai W (2016) Oncogene 35: 1847-56 Phase resetting light pulses induce Per1 and persistent spike activity in a subpopulation of biological clock neurons. Kuhlman SJ, Silver R, Le Sauter J, Bult-Ito A, McMahon DG (2003) J Neurosci 23: 1441-50 Gastrin-releasing peptide mediates light-like resetting of the suprachiasmatic nucleus circadian pacemaker through cAMP response element-binding protein and Per1 activation. Gamble KL, Allen GC, Zhou T, McMahon DG (2007) J Neurosci 27: 12078-87 Relationship between carbamoyl-phosphate synthetase genotype and systemic vascular function. Summar ML, Gainer JV, Pretorius M, Malave H, Harris S, Hall LD, Weisberg A, Vaughan DE, Christman BW, Brown NJ (2004) Hypertension 43: 186-91 Endogenous NO regulates plasminogen activator inhibitor-1 during angiotensin-converting enzyme inhibition. Brown NJ, Muldowney JA, Vaughan DE (2006) Hypertension 47: 441-8 NO synthase inhibition increases aldosterone in humans. Muldowney JA, Davis SN, Vaughan DE, Brown NJ (2004) Hypertension 44: 739-45 Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects. Simmler LD, Hysek CM, Liechti ME (2011) J Clin Endocrinol Metab 96: 2844-50 Compound heterozygous mutations (Arg 239----stop, Pro 342----Thr) in the CYP17 (P45017 alpha) gene lead to ambiguous external genitalia in a male patient with partial combined 17 alpha-hydroxylase/17,20-lyase deficiency. Ahlgren R, Yanase T, Simpson ER, Winter JS, Waterman MR (1992) J Clin Endocrinol Metab 74: 667-72 Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia. Gustavson SM, Rajotte RV, Hunkeler D, Lakey JR, Edgerton DS, Neal DW, Snead WL, Penaloza AR, Cherrington AD (2005) Am J Transplant 5: 2368-77 Role of the endothelium in modulation of the acetylcholine vasoconstrictor response in porcine coronary microvessels. Myers PR, Banitt PF, Guerra R, Harrison DG (1991) Cardiovasc Res 25: 129-37
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.