Keyword Connections

•  Amy Major
•  Danyvid Olivares-Villagomez
•  Eric Sebzda

•  Holly Algood
•  Kyra Richter
•  Nishitha Reddy

•  Peggy Kendall
•  Rachel Bonami

Resources

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Communities

• James (Tom) Thomas Laboratory
• Madhur Lab

Publications

• Tumor-infiltrating lymphocytes and interleukin-2 in melanomas.
  Sondel PM, Sosman JA, Hank JA, Kohler PC, Storer B
  (1989) N Engl J Med 320: 1418-9
• CD4+ counts in seronegative homosexual men. The Multicenter AIDS Cohort Study.
  Vermund SH, Hoover DR, Chen K
  (1993) N Engl J Med 328: 442
• The effects on survival of early treatment of human immunodeficiency virus infection.
  Graham NM, Zeger SL, Park LP, Vermund SH, Detels R, Rinaldo CR, Phair JP
  (1992) N Engl J Med 326: 1037-42
• Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
  Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Krischer JP, Skyler JS, Type 1 Diabetes TrialNet Abatacept Study Group
  (2011) Lancet 378: 412-9
• Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study.
  Graham NM, Zeger SL, Park LP, Phair JP, Detels R, Vermund SH, Ho M, Saah AJ
  (1991) Lancet 338: 265-9
• A severe combined immunodeficiency mutation in the mouse.
  Bosma GC, Custer RP, Bosma MJ
  (1983) Nature 301: 527-30
• Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.
  Rickert RC, Rajewsky K, Roes J
  (1995) Nature 376: 352-5
• Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
  Sapparapu G, Fernandez E, Kose N, Bin Cao , Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE
  (2016) Nature 540: 443-447
• Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system.
  Cho SH, Raybuck AL, Stengel K, Wei M, Beck TC, Volanakis E, Thomas JW, Hiebert S, Haase VH, Boothby MR
  (2016) Nature 537: 234-238
• Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
  Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR
  (2017) Nature 545: 243-247
• T cells from patients with Parkinson's disease recognize α-synuclein peptides.
  Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, Dillon MB, Carpenter C, Weiskopf D, Phillips E, Mallal S, Peters B, Frazier A, Lindestam Arlehamn CS, Sette A
  (2017) Nature 546: 656-661
• Amphibians acquire resistance to live and dead fungus overcoming fungal immunosuppression.
  McMahon TA, Sears BF, Venesky MD, Bessler SM, Brown JM, Deutsch K, Halstead NT, Lentz G, Tenouri N, Young S, Civitello DJ, Ortega N, Fites JS, Reinert LK, Rollins-Smith LA, Raffel TR, Rohr JR
  (2014) Nature 511: 224-7
• Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis.
  Vesa J, Hellsten E, Verkruyse LA, Camp LA, Rapola J, Santavuori P, Hofmann SL, Peltonen L
  (1995) Nature 376: 584-7
• High frequency of shared clonotypes in human B cell receptor repertoires.
  Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE
  (2019) Nature 566: 398-402
• Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.
  Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, Crowe JE
  (2008) Nature 455: 532-6
• Very high frequency of lymphoma induction by a chemical carcinogen in pim-1 transgenic mice.
  Breuer M, Slebos R, Verbeek S, van Lohuizen M, Wientjens E, Berns A
  (1989) Nature 340: 61-3
• Human genetics: an expression of interest.
  Cox NJ
  (2004) Nature 430: 733-4
• Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons.
  Chao JR, Parganas E, Boyd K, Hong CY, Opferman JT, Ihle JN
  (2008) Nature 452: 98-102
• Overview of the Alliance for Cellular Signaling.
  Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, Gold M, Weiss A, Stull JT, Berridge MJ, Cantley LC, Catterall WA, Coughlin SR, Olson EN, Smith TF, Brugge JS, Botstein D, Dixon JE, Hunter T, Lefkowitz RJ, Pawson AJ, Sternberg PW, Varmus H, Subramaniam S, Sinkovits RS, Li J, Mock D, Ning Y, Saunders B, Sternweis PC, Hilgemann D, Scheuermann RH, DeCamp D, Hsueh R, Lin KM, Ni Y, Seaman WE, Simpson PC, O'Connell TD, Roach T, Simon MI, Choi S, Eversole-Cire P, Fraser I, Mumby MC, Zhao Y, Brekken D, Shu H, Meyer T, Chandy G, Heo WD, Liou J, O'Rourke N, Verghese M, Mumby SM, Han H, Brown HA, Forrester JS, Ivanova P, Milne SB, Casey PJ, Harden TK, Arkin AP, Doyle J, Gray ML, Meyer T, Michnick S, Schmidt MA, Toner M, Tsien RY, Natarajan M, Ranganathan R, Sambrano GR, Participating investigators and scientists of the Alliance for Cellular Signaling
  (2002) Nature 420: 703-6
• The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
  Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA
  (2007) Nature 450: 566-9
• Syk tyrosine kinase required for mouse viability and B-cell development.
  Cheng AM, Rowley B, Pao W, Hayday A, Bolen JB, Pawson T
  (1995) Nature 378: 303-6
• Genome-wide association study of blood pressure and hypertension.
  Levy D, Ehret GB, Rice K, Verwoert GC, Launer LJ, Dehghan A, Glazer NL, Morrison AC, Johnson AD, Aspelund T, Aulchenko Y, Lumley T, Köttgen A, Vasan RS, Rivadeneira F, Eiriksdottir G, Guo X, Arking DE, Mitchell GF, Mattace-Raso FU, Smith AV, Taylor K, Scharpf RB, Hwang SJ, Sijbrands EJ, Bis J, Harris TB, Ganesh SK, O'Donnell CJ, Hofman A, Rotter JI, Coresh J, Benjamin EJ, Uitterlinden AG, Heiss G, Fox CS, Witteman JC, Boerwinkle E, Wang TJ, Gudnason V, Larson MG, Chakravarti A, Psaty BM, van Duijn CM
  (2009) Nat Genet 41: 677-87
• Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death.
  Hicks GG, Singh N, Nashabi A, Mai S, Bozek G, Klewes L, Arapovic D, White EK, Koury MJ, Oltz EM, Van Kaer L, Ruley HE
  (2000) Nat Genet 24: 175-9
• Reciprocal regulation between natural killer cells and autoreactive T cells.
  Shi FD, Van Kaer L
  (2006) Nat Rev Immunol 6: 751-60
• NKT cells: what's in a name?
  Godfrey DI, MacDonald HR, Kronenberg M, Smyth MJ, Van Kaer L
  (2004) Nat Rev Immunol 4: 231-7
• alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles.
  Van Kaer L
  (2005) Nat Rev Immunol 5: 31-42
• Evidence for a differential avidity model of T cell selection in the thymus.
  Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S
  (1994) Cell 76: 651-63
• Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier.
  Arima Y, Harada M, Kamimura D, Park JH, Kawano F, Yull FE, Kawamoto T, Iwakura Y, Betz UA, Márquez G, Blackwell TS, Ohira Y, Hirano T, Murakami M
  (2012) Cell 148: 447-57