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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Publications
- Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE
(2015) Nature 523: 561-7 - Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Karakas E, Simorowski N, Furukawa H
(2011) Nature 475: 249-53 - Right and left myocardial antioxidant responses during heart failure subsequent to myocardial infarction.
Hill MF, Singal PK
(1997) Circulation 96: 2414-20 - Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD
(2009) J Clin Invest 119: 573-81 - HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ
(2018) Cell Host Microbe 24: 703-716.e3 - Molecular dendritic transporter nanoparticle vectors provide efficient intracellular delivery of peptides.
Hamilton SK, Harth E
(2009) ACS Nano 3: 402-10 - Cole-Carpenter syndrome is caused by a heterozygous missense mutation in P4HB.
Rauch F, Fahiminiya S, Majewski J, Carrot-Zhang J, Boudko S, Glorieux F, Mort JS, Bächinger HP, Moffatt P
(2015) Am J Hum Genet 96: 425-31 - A model of anthrax toxin lethal factor bound to protective antigen.
Lacy DB, Lin HC, Melnyk RA, Schueler-Furman O, Reither L, Cunningham K, Baker D, Collier RJ
(2005) Proc Natl Acad Sci U S A 102: 16409-14 - Collagen triple-helix formation in all-trans chains proceeds by a nucleation/growth mechanism with a purely entropic barrier.
Bachmann A, Kiefhaber T, Boudko S, Engel J, Bächinger HP
(2005) Proc Natl Acad Sci U S A 102: 13897-902 - Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex.
Matsuura H, Kirschner AN, Longnecker R, Jardetzky TS
(2010) Proc Natl Acad Sci U S A 107: 22641-6 - Hypoxia and Reactive Oxygen Species Homeostasis in Mesenchymal Progenitor Cells Define a Molecular Mechanism for Fracture Nonunion.
Muinos-López E, Ripalda-Cemboráin P, López-Martínez T, González-Gil AB, Lamo-Espinosa JM, Valentí A, Mortlock DP, Valentí JR, Prósper F, Granero-Moltó F
(2016) Stem Cells 34: 2342-53 - HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, Kass DA, Mahaney JE, Paolocci N
(2013) Antioxid Redox Signal 19: 1185-97 - GSH is required to recycle ascorbic acid in cultured liver cell lines.
Li X, Qu ZC, May JM
(2001) Antioxid Redox Signal 3: 1089-97 - C-terminus of heat shock cognate 70 interacting protein increases following stroke and impairs survival against acute oxidative stress.
Stankowski JN, Zeiger SL, Cohen EL, DeFranco DB, Cai J, McLaughlin B
(2011) Antioxid Redox Signal 14: 1787-801 - Association between adherence to the Mediterranean diet and oxidative stress.
Dai J, Jones DP, Goldberg J, Ziegler TR, Bostick RM, Wilson PW, Manatunga AK, Shallenberger L, Jones L, Vaccarino V
(2008) Am J Clin Nutr 88: 1364-70 - Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II.
Widder JD, Guzik TJ, Mueller CF, Clempus RE, Schmidt HH, Dikalov SI, Griendling KK, Jones DP, Harrison DG
(2007) Arterioscler Thromb Vasc Biol 27: 762-8 - Pathogenetic studies of hexane and carbon disulfide neurotoxicity.
Graham DG, Amarnath V, Valentine WM, Pyle SJ, Anthony DC
(1995) Crit Rev Toxicol 25: 91-112 - A model for the solution structure of the rod arrestin tetramer.
Hanson SM, Dawson ES, Francis DJ, Van Eps N, Klug CS, Hubbell WL, Meiler J, Gurevich VV
(2008) Structure 16: 924-34 - Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor.
Vilar M, Charalampopoulos I, Kenchappa RS, Reversi A, Klos-Applequist JM, Karaca E, Simi A, Spuch C, Choi S, Friedman WJ, Ericson J, Schiavo G, Carter BD, Ibáñez CF
(2009) J Cell Sci 122: 3351-7 - Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature.
Geng L, Rachakonda G, Morré DJ, Morré DM, Crooks PA, Sonar VN, Roti JL, Rogers BE, Greco S, Ye F, Salleng KJ, Sasi S, Freeman ML, Sekhar KR
(2009) FASEB J 23: 2986-95 - The Ig-like domain of tapasin influences intermolecular interactions.
Turnquist HR, Petersen JL, Vargas SE, McIlhaney MM, Bedows E, Mayer WE, Grandea AG, Van Kaer L, Solheim JC
(2004) J Immunol 172: 2976-84 - Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.
Jakupoglu C, Przemeck GK, Schneider M, Moreno SG, Mayr N, Hatzopoulos AK, de Angelis MH, Wurst W, Bornkamm GW, Brielmeier M, Conrad M
(2005) Mol Cell Biol 25: 1980-8 - Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.
Conrad M, Jakupoglu C, Moreno SG, Lippl S, Banjac A, Schneider M, Beck H, Hatzopoulos AK, Just U, Sinowatz F, Schmahl W, Chien KR, Wurst W, Bornkamm GW, Brielmeier M
(2004) Mol Cell Biol 24: 9414-23 - Trapping redox partnerships in oxidant-sensitive proteins with a small, thiol-reactive cross-linker.
Allan KM, Loberg MA, Chepngeno J, Hurtig JE, Tripathi S, Kang MG, Allotey JK, Widdershins AH, Pilat JM, Sizek HJ, Murphy WJ, Naticchia MR, David JB, Morano KA, West JD
(2016) Free Radic Biol Med 101: 356-366 - Vitamin C recycling and function in human monocytic U-937 cells.
May JM, Mendiratta S, Qu ZC, Loggins E
(1999) Free Radic Biol Med 26: 1513-23 - Enzyme-dependent ascorbate recycling in human erythrocytes: role of thioredoxin reductase.
Mendiratta S, Qu ZC, May JM
(1998) Free Radic Biol Med 25: 221-8 - Greater propensity of diabetic myocardium for oxidative stress after myocardial infarction is associated with the development of heart failure.
Smith HM, Hamblin M, Hill MF
(2005) J Mol Cell Cardiol 39: 657-65 - Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design.
Kwon YD, Georgiev IS, Ofek G, Zhang B, Asokan M, Bailer RT, Bao A, Caruso W, Chen X, Choe M, Druz A, Ko SY, Louder MK, McKee K, O'Dell S, Pegu A, Rudicell RS, Shi W, Wang K, Yang Y, Alger M, Bender MF, Carlton K, Cooper JW, Blinn J, Eudailey J, Lloyd K, Parks R, Alam SM, Haynes BF, Padte NN, Yu J, Ho DD, Huang J, Connors M, Schwartz RM, Mascola JR, Kwong PD
(2016) J Virol 90: 5899-5914 - Protein disulfide isomerase serves as a molecular chaperone to maintain estrogen receptor alpha structure and function.
Schultz-Norton JR, McDonald WH, Yates JR, Nardulli AM
(2006) Mol Endocrinol 20: 1982-95 - Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function.
Pi J, Bai Y, Daniel KW, Liu D, Lyght O, Edelstein D, Brownlee M, Corkey BE, Collins S
(2009) Endocrinology 150: 3040-8 - Hotspots of age-related protein degradation: the importance of neighboring residues for the formation of non-disulfide crosslinks derived from cysteine.
Friedrich MG, Wang Z, Oakley AJ, Schey KL, Truscott RJW
(2017) Biochem J 474: 2475-2487 - Reduction of dehydroascorbate to ascorbate by the selenoenzyme thioredoxin reductase.
May JM, Mendiratta S, Hill KE, Burk RF
(1997) J Biol Chem 272: 22607-10 - Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of alpha3, alpha4, and alpha5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome.
Gunwar S, Ballester F, Noelken ME, Sado Y, Ninomiya Y, Hudson BG
(1998) J Biol Chem 273: 8767-75 - Modulation of the structure, catalytic activity, and fidelity of African swine fever virus DNA polymerase X by a reversible disulfide switch.
Voehler MW, Eoff RL, McDonald WH, Guengerich FP, Stone MP
(2009) J Biol Chem 284: 18434-44 - Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes.
Sundaramoorthy M, Meiyappan M, Todd P, Hudson BG
(2002) J Biol Chem 277: 31142-53 - Trimerization and triple helix stabilization of the collagen XIX NC2 domain.
Boudko SP, Engel J, Bächinger HP
(2008) J Biol Chem 283: 34345-51 - Intestinal basement membrane of Ascaris suum. Properties of the collagenous domain.
Hung CH, Butkowski RJ, Hudson BG
(1980) J Biol Chem 255: 4964-71 - Properties of the globular domain of type IV collagen and its relationship to the Goodpasture antigen.
Butkowski RJ, Wieslander J, Wisdom BJ, Barr JF, Noelken ME, Hudson BG
(1985) J Biol Chem 260: 3739-47 - Fractionation of glycoprotein components of the reduced alkylated renal glomerular basement membrane.
Hudson BG, Spiro RG
(1972) J Biol Chem 247: 4239-47 - Assembly of the epithelial Na+ channel evaluated using sucrose gradient sedimentation analysis.
Cheng C, Prince LS, Snyder PM, Welsh MJ
(1998) J Biol Chem 273: 22693-700
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