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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Immunoglobulin G are shown below. Double-click or tap a node for more information.
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- New drugs for rheumatoid arthritis.
Olsen NJ, Stein CM
(2004) N Engl J Med 350: 2167-79 - Milk and membranous nephropathy.
Fogo AB
(2011) N Engl J Med 364: 2158-9 - Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F
(2014) Nat Med 20: 904-10 - Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.
Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE
(2018) Immunity 49: 363-374.e10 - High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2-KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/C509801.
Kirkwood JM, Ibrahim JG, Sosman JA, Sondak VK, Agarwala SS, Ernstoff MS, Rao U
(2001) J Clin Oncol 19: 2370-80 - Antibody to platelet/endothelial cell adhesion molecule-1 reduces myocardial infarct size in a rat model of ischemia-reperfusion injury.
Gumina RJ, el Schultz J, Yao Z, Kenny D, Warltier DC, Newman PJ, Gross GJ
(1996) Circulation 94: 3327-33 - A radioimmunometric antibody-binding assay for evaluation of xenoantisera to melanoma-associated antigens.
McCabe RP, Quaranta V, Frugis L, Ferrone S, Reisfeld RA
(1979) J Natl Cancer Inst 62: 455-63 - Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
Wen L, Pao W, Wong FS, Peng Q, Craft J, Zheng B, Kelsoe G, Dianda L, Owen MJ, Hayday AC
(1996) J Exp Med 183: 2271-82 - In vivo function of an interleukin 2 receptor beta chain (IL-2Rbeta)/IL-4Ralpha cytokine receptor chimera potentiates allergic airway disease.
Youn J, Chen J, Goenka S, Aronica MA, Mora AL, Correa V, Sheller JR, Boothby M
(1998) J Exp Med 188: 1803-16 - Complement-dependent platelet injury by staphylococcal protein A.
Hawiger J, Marney SR, Colley DG, Des Prez RM
(1972) J Exp Med 136: 68-80 - KSR1 protects from interleukin-10 deficiency-induced colitis in mice by suppressing T-lymphocyte interferon-γ production.
Goettel JA, Scott Algood HM, Olivares-Villagómez D, Washington MK, Chaturvedi R, Wilson KT, Van Kaer L, Polk DB
(2011) Gastroenterology 140: 265-74 - Proteolytic cleavage and loss of function of biologic agents that neutralize tumor necrosis factor in the mucosa of patients with inflammatory bowel disease.
Biancheri P, Brezski RJ, Di Sabatino A, Greenplate AR, Soring KL, Corazza GR, Kok KB, Rovedatti L, Vossenkämper A, Ahmad N, Snoek SA, Vermeire S, Rutgeerts P, Jordan RE, MacDonald TT
(2015) Gastroenterology 149: 1564-1574.e3 - Serum neutralizing antibody response to the vacuolating cytotoxin of Helicobacter pylori.
Cover TL, Cao P, Murthy UK, Sipple MS, Blaser MJ
(1992) J Clin Invest 90: 913-8 - Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.
Arteaga CL, Hurd SD, Winnier AR, Johnson MD, Fendly BM, Forbes JT
(1993) J Clin Invest 92: 2569-76 - Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.
Muraoka RS, Dumont N, Ritter CA, Dugger TC, Brantley DM, Chen J, Easterly E, Roebuck LR, Ryan S, Gotwals PJ, Koteliansky V, Arteaga CL
(2002) J Clin Invest 109: 1551-9 - Staphylococci-induced human platelet injury mediated by protein A and immunoglobulin G Fc fragment receptor.
Hawiger J, Steckley S, Hammond D, Cheng C, Timmons S, Glick AD, Des Prez RM
(1979) J Clin Invest 64: 931-7 - HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ
(2018) Cell Host Microbe 24: 703-716.e3 - Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation.
Vieira OV, Botelho RJ, Rameh L, Brachmann SM, Matsuo T, Davidson HW, Schreiber A, Backer JM, Cantley LC, Grinstein S
(2001) J Cell Biol 155: 19-25 - Evaluation of candidate vaccine approaches for MERS-CoV.
Wang L, Shi W, Joyce MG, Modjarrad K, Zhang Y, Leung K, Lees CR, Zhou T, Yassine HM, Kanekiyo M, Yang ZY, Chen X, Becker MM, Freeman M, Vogel L, Johnson JC, Olinger G, Todd JP, Bagci U, Solomon J, Mollura DJ, Hensley L, Jahrling P, Denison MR, Rao SS, Subbarao K, Kwong PD, Mascola JR, Kong WP, Graham BS
(2015) Nat Commun 6: 7712 - The alpha 3 chain of type IV collagen induces autoimmune Goodpasture syndrome.
Kalluri R, Gattone VH, Noelken ME, Hudson BG
(1994) Proc Natl Acad Sci U S A 91: 6201-5 - Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge.
Brezski RJ, Vafa O, Petrone D, Tam SH, Powers G, Ryan MH, Luongo JL, Oberholtzer A, Knight DM, Jordan RE
(2009) Proc Natl Acad Sci U S A 106: 17864-9 - Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.
Kanner SB, Reynolds AB, Vines RR, Parsons JT
(1990) Proc Natl Acad Sci U S A 87: 3328-32 - Gamma delta T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells.
Pao W, Wen L, Smith AL, Gulbranson-Judge A, Zheng B, Kelsoe G, MacLennan IC, Owen MJ, Hayday AC
(1996) Curr Biol 6: 1317-25 - Etanercept for treatment of idiopathic pneumonia syndrome after allogeneic hematopoietic stem cell transplantation.
Frangoul H, Koyama T, Domm J
(2009) Blood 113: 2868-9; author reply 2869 - Tolerance induction to a mammalian blood group-like carbohydrate antigen by syngeneic lymphocytes expressing the antigen.
Ogawa H, Yin DP, Shen J, Galili U
(2003) Blood 101: 2318-20 - FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.
Serezani CH, Aronoff DM, Sitrin RG, Peters-Golden M
(2009) Blood 114: 3316-24 - Quaternary epitopes of α345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB
(2013) J Am Soc Nephrol 24: 889-95 - Th1 and Th17 cells induce proliferative glomerulonephritis.
Summers SA, Steinmetz OM, Li M, Kausman JY, Semple T, Edgtton KL, Borza DB, Braley H, Holdsworth SR, Kitching AR
(2009) J Am Soc Nephrol 20: 2518-24 - Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: a protective role for IFN-gamma.
Kitching AR, Turner AL, Semple T, Li M, Edgtton KL, Wilson GR, Timoshanko JR, Hudson BG, Holdsworth SR
(2004) J Am Soc Nephrol 15: 1764-74 - Neonatal Fc receptor promotes immune complex-mediated glomerular disease.
Olaru F, Luo W, Suleiman H, St John PL, Ge L, Mezo AR, Shaw AS, Abrahamson DR, Miner JH, Borza DB
(2014) J Am Soc Nephrol 25: 918-25 - Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.
Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, Stemmermann GN, Nomura A
(1995) Cancer Res 55: 2111-5 - Preference for IgG mAb binding insulin in solution or on surfaces is related to immunoglobulin variable region structures.
Tikhomirov OY, Thomas JW
(1997) J Autoimmun 10: 541-9 - Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria.
Motoyoshi Y, Matsusaka T, Saito A, Pastan I, Willnow TE, Mizutani S, Ichikawa I
(2008) Kidney Int 74: 1262-9 - Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG, Gannon M, Powers AC, Dempsey PJ
(2010) Diabetes 59: 3090-8 - Consider Changing the Horse for Your CAR-T?
Wilson MH
(2018) Mol Ther 26: 1873-1874 - The period gene encodes a predominantly nuclear protein in adult Drosophila.
Liu X, Zwiebel LJ, Hinton D, Benzer S, Hall JC, Rosbash M
(1992) J Neurosci 12: 2735-44 - Application of C flux analysis to identify high-productivity CHO metabolic phenotypes.
Templeton N, Smith KD, McAtee-Pereira AG, Dorai H, Betenbaugh MJ, Lang SE, Young JD
(2017) Metab Eng 43: 218-225 - Characterization of human anti-luteinizing hormone-releasing hormone (LRH) antibodies in the serum of a patient with isolated gonadotropin deficiency treated with synthetic LRH.
Lindner J, McNeil LW, Marney S, Conway M, Rivier J, Vale W, Rabin D
(1981) J Clin Endocrinol Metab 52: 267-70 - Helicobacter pylori infection in Japanese patients with adenocarcinoma of the stomach.
Blaser MJ, Kobayashi K, Cover TL, Cao P, Feurer ID, Pérez-Pérez GI
(1993) Int J Cancer 55: 799-802 - Lack of specificity of endoglin expression for tumor blood vessels.
Balza E, Castellani P, Zijlstra A, Neri D, Zardi L, Siri A
(2001) Int J Cancer 94: 579-85
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