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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to T-Lymphocytes are shown below. Double-click or tap a node for more information.
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Publications
- Tumor-infiltrating lymphocytes and interleukin-2 in melanomas.
Sondel PM, Sosman JA, Hank JA, Kohler PC, Storer B
(1989) N Engl J Med 320: 1418-9 - CD4+ counts in seronegative homosexual men. The Multicenter AIDS Cohort Study.
Vermund SH, Hoover DR, Chen K
(1993) N Engl J Med 328: 442 - The effects on survival of early treatment of human immunodeficiency virus infection.
Graham NM, Zeger SL, Park LP, Vermund SH, Detels R, Rinaldo CR, Phair JP
(1992) N Engl J Med 326: 1037-42 - Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study.
Graham NM, Zeger SL, Park LP, Phair JP, Detels R, Vermund SH, Ho M, Saah AJ
(1991) Lancet 338: 265-9 - Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Krischer JP, Skyler JS, Type 1 Diabetes TrialNet Abatacept Study Group
(2011) Lancet 378: 412-9 - Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR
(2017) Nature 545: 243-247 - Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.
Rickert RC, Rajewsky K, Roes J
(1995) Nature 376: 352-5 - The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA
(2007) Nature 450: 566-9 - Very high frequency of lymphoma induction by a chemical carcinogen in pim-1 transgenic mice.
Breuer M, Slebos R, Verbeek S, van Lohuizen M, Wientjens E, Berns A
(1989) Nature 340: 61-3 - NKT cells: what's in a name?
Godfrey DI, MacDonald HR, Kronenberg M, Smyth MJ, Van Kaer L
(2004) Nat Rev Immunol 4: 231-7 - alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles.
Van Kaer L
(2005) Nat Rev Immunol 5: 31-42 - Reciprocal regulation between natural killer cells and autoreactive T cells.
Shi FD, Van Kaer L
(2006) Nat Rev Immunol 6: 751-60 - H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection.
Martin WD, Hicks GG, Mendiratta SK, Leva HI, Ruley HE, Van Kaer L
(1996) Cell 84: 543-50 - Evidence for a differential avidity model of T cell selection in the thymus.
Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S
(1994) Cell 76: 651-63 - Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.
Lau KS, Partridge EA, Grigorian A, Silvescu CI, Reinhold VN, Demetriou M, Dennis JW
(2007) Cell 129: 123-34 - Transgenic HLA-DR alpha faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to E alpha in E alpha 0 mutant mice.
Lawrance SK, Karlsson L, Price J, Quaranta V, Ron Y, Sprent J, Peterson PA
(1989) Cell 58: 583-94 - Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus.
Ashton-Rickardt PG, Van Kaer L, Schumacher TN, Ploegh HL, Tonegawa S
(1993) Cell 73: 1041-9 - Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g.
Gérard A, Patino-Lopez G, Beemiller P, Nambiar R, Ben-Aissa K, Liu Y, Totah FJ, Tyska MJ, Shaw S, Krummel MF
(2014) Cell 158: 492-505 - Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier.
Arima Y, Harada M, Kamimura D, Park JH, Kawano F, Yull FE, Kawamoto T, Iwakura Y, Betz UA, Márquez G, Blackwell TS, Ohira Y, Hirano T, Murakami M
(2012) Cell 148: 447-57 - Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC
(2018) Cell 175: 1780-1795.e19 - Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor.
Ito K, Van Kaer L, Bonneville M, Hsu S, Murphy DB, Tonegawa S
(1990) Cell 62: 549-61 - TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells.
Van Kaer L, Ashton-Rickardt PG, Ploegh HL, Tonegawa S
(1992) Cell 71: 1205-14 - Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.
Tian M, Cheng C, Chen X, Duan H, Cheng HL, Dao M, Sheng Z, Kimble M, Wang L, Lin S, Schmidt SD, Du Z, Joyce MG, Chen Y, DeKosky BJ, Chen Y, Normandin E, Cantor E, Chen RE, Doria-Rose NA, Zhang Y, Shi W, Kong WP, Choe M, Henry AR, Laboune F, Georgiev IS, Huang PY, Jain S, McGuire AT, Georgeson E, Menis S, Douek DC, Schief WR, Stamatatos L, Kwong PD, Shapiro L, Haynes BF, Mascola JR, Alt FW
(2016) Cell 166: 1471-1484.e18 - Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion.
Delong T, Wiles TA, Baker RL, Bradley B, Barbour G, Reisdorph R, Armstrong M, Powell RL, Reisdorph N, Kumar N, Elso CM, DeNicola M, Bottino R, Powers AC, Harlan DM, Kent SC, Mannering SI, Haskins K
(2016) Science 351: 711-4 - The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
International HIV Controllers Study, Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M
(2010) Science 330: 1551-7 - Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol.
Joyce S, Woods AS, Yewdell JW, Bennink JR, De Silva AD, Boesteanu A, Balk SP, Cotter RJ, Brutkiewicz RR
(1998) Science 279: 1541-4 - Interleukin-4 and interleukin-13 signaling connections maps.
Kelly-Welch AE, Hanson EM, Boothby MR, Keegan AD
(2003) Science 300: 1527-8 - A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.
Westphal RS, Anderson KA, Means AR, Wadzinski BE
(1998) Science 280: 1258-61 - Natural killer cells determine the outcome of B cell-mediated autoimmunity.
Shi FD, Wang HB, Li H, Hong S, Taniguchi M, Link H, Van Kaer L, Ljunggren HG
(2000) Nat Immunol 1: 245-51 - Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns.
Sebzda E, Zou Z, Lee JS, Wang T, Kahn ML
(2008) Nat Immunol 9: 292-300 - A 'Tsc, Tsc' keeps the kids quie(scen)t and holds down ROS.
Boothby M, Lee K
(2011) Nat Immunol 12: 811-2 - Viral evasion of antigen presentation: not just for peptides anymore.
Van Kaer L, Joyce S
(2006) Nat Immunol 7: 795-7 - The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.
Liu G, Burns S, Huang G, Boyd K, Proia RL, Flavell RA, Chi H
(2009) Nat Immunol 10: 769-77 - Mucosal memory CD8⁺ T cells are selected in the periphery by an MHC class I molecule.
Huang Y, Park Y, Wang-Zhu Y, Larange A, Arens R, Bernardo I, Olivares-Villagómez D, Herndler-Brandstetter D, Abraham N, Grubeck-Loebenstein B, Schoenberger SP, Van Kaer L, Kronenberg M, Teitell MA, Cheroutre H
(2011) Nat Immunol 12: 1086-95 - Characterizing cell subsets using marker enrichment modeling.
Diggins KE, Greenplate AR, Leelatian N, Wogsland CE, Irish JM
(2017) Nat Methods 14: 275-278 - Natural killer T cells and CD8+ T cells are dispensable for T cell-dependent allergic airway inflammation.
Das J, Eynott P, Jupp R, Bothwell A, Van Kaer L, Shi Y, Das G
(2006) Nat Med 12: 1345-6; author reply 1347
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