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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Protein Stability are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Protein Stability.
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- Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis.
Marinko JT, Huang H, Penn WD, Capra JA, Schlebach JP, Sanders CR
(2019) Chem Rev 119: 5537-5606 - Proof of principle for epitope-focused vaccine design.
Correia BE, Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, Serra AM, Adachi Y, Holmes MA, Li Y, Klevit RE, Graham BS, Wyatt RT, Baker D, Strong RK, Crowe JE, Johnson PR, Schief WR
(2014) Nature 507: 201-6 - SOSS1/2: Sensors of single-stranded DNA at a break.
Nam EA, Cortez D
(2009) Mol Cell 35: 258-9 - Protonation drives the conformational switch in the multidrug transporter LmrP.
Masureel M, Martens C, Stein RA, Mishra S, Ruysschaert JM, Mchaourab HS, Govaerts C
(2014) Nat Chem Biol 10: 149-55 - Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction.
Gaskill CF, Carrier EJ, Kropski JA, Bloodworth NC, Menon S, Foronjy RF, Taketo MM, Hong CC, Austin ED, West JD, Means AL, Loyd JE, Merryman WD, Hemnes AR, De Langhe S, Blackwell TS, Klemm DJ, Majka SM
(2017) J Clin Invest 127: 2262-2276 - Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
Zheng X, Zhai B, Koivunen P, Shin SJ, Lu G, Liu J, Geisen C, Chakraborty AA, Moslehi JJ, Smalley DM, Wei X, Chen X, Chen Z, Beres JM, Zhang J, Tsao JL, Brenner MC, Zhang Y, Fan C, DePinho RA, Paik J, Gygi SP, Kaelin WG, Zhang Q
(2014) Genes Dev 28: 1429-44 - Conformational Stability and Pathogenic Misfolding of the Integral Membrane Protein PMP22.
Schlebach JP, Narayan M, Alford C, Mittendorf KF, Carter BD, Li J, Sanders CR
(2015) J Am Chem Soc 137: 8758-68 - Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain.
Cooley CB, Ryno LM, Plate L, Morgan GJ, Hulleman JD, Kelly JW, Wiseman RL
(2014) Proc Natl Acad Sci U S A 111: 13046-51 - Conformation of receptor-bound visual arrestin.
Kim M, Vishnivetskiy SA, Van Eps N, Alexander NS, Cleghorn WM, Zhan X, Hanson SM, Morizumi T, Ernst OP, Meiler J, Gurevich VV, Hubbell WL
(2012) Proc Natl Acad Sci U S A 109: 18407-12 - Computational design of protein-ligand interfaces: potential in therapeutic development.
Morin A, Meiler J, Mizoue LS
(2011) Trends Biotechnol 29: 159-66 - Regulation of ERBB2 receptor by t-DARPP mediates trastuzumab resistance in human esophageal adenocarcinoma.
Hong J, Katsha A, Lu P, Shyr Y, Belkhiri A, El-Rifai W
(2012) Cancer Res 72: 4504-14 - Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.
Heuckmann JM, Balke-Want H, Malchers F, Peifer M, Sos ML, Koker M, Meder L, Lovly CM, Heukamp LC, Pao W, Küppers R, Thomas RK
(2012) Clin Cancer Res 18: 4682-90 - Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.
Ratnapriya R, Zhan X, Fariss RN, Branham KE, Zipprer D, Chakarova CF, Sergeev YV, Campos MM, Othman M, Friedman JS, Maminishkis A, Waseem NH, Brooks M, Rajasimha HK, Edwards AO, Lotery A, Klein BE, Truitt BJ, Li B, Schaumberg DA, Morgan DJ, Morrison MA, Souied E, Tsironi EE, Grassmann F, Fishman GA, Silvestri G, Scholl HP, Kim IK, Ramke J, Tuo J, Merriam JE, Merriam JC, Park KH, Olson LM, Farrer LA, Johnson MP, Peachey NS, Lathrop M, Baron RV, Igo RP, Klein R, Hagstrom SA, Kamatani Y, Martin TM, Jiang Y, Conley Y, Sahel JA, Zack DJ, Chan CC, Pericak-Vance MA, Jacobson SG, Gorin MB, Klein ML, Allikmets R, Iyengar SK, Weber BH, Haines JL, Léveillard T, Deangelis MM, Stambolian D, Weeks DE, Bhattacharya SS, Chew EY, Heckenlively JR, Abecasis GR, Swaroop A
(2014) Hum Mol Genet 23: 5827-37 - SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.
Lu W, Liu S, Li B, Xie Y, Izban MG, Ballard BR, Sathyanarayana SA, Adunyah SE, Matusik RJ, Chen Z
(2017) Oncogene 36: 1364-1373 - Global stability of plasma proteomes for mass spectrometry-based analyses.
Zimmerman LJ, Li M, Yarbrough WG, Slebos RJ, Liebler DC
(2012) Mol Cell Proteomics 11: M111.014340 - HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.
Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, Kass DA, Mahaney JE, Paolocci N
(2013) Antioxid Redox Signal 19: 1185-97 - Insights into congenital stationary night blindness based on the structure of G90D rhodopsin.
Singhal A, Ostermaier MK, Vishnivetskiy SA, Panneels V, Homan KT, Tesmer JJ, Veprintsev D, Deupi X, Gurevich VV, Schertler GF, Standfuss J
(2013) EMBO Rep 14: 520-6 - ATF6 activation reduces the secretion and extracellular aggregation of destabilized variants of an amyloidogenic protein.
Chen JJ, Genereux JC, Qu S, Hulleman JD, Shoulders MD, Wiseman RL
(2014) Chem Biol 21: 1564-74 - Structural basis for the Trembler-J phenotype of Charcot-Marie-Tooth disease.
Sakakura M, Hadziselimovic A, Wang Z, Schey KL, Sanders CR
(2011) Structure 19: 1160-9 - Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects.
Yang R, Shi J, Byeon IJ, Ahn J, Sheehan JH, Meiler J, Gronenborn AM, Aiken C
(2012) Retrovirology 9: 30 - LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.
Layer JH, Alford CE, McDonald WH, Davé UP
(2016) Mol Cell Biol 36: 488-506 - Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.
Chuang GY, Geng H, Pancera M, Xu K, Cheng C, Acharya P, Chambers M, Druz A, Tsybovsky Y, Wanninger TG, Yang Y, Doria-Rose NA, Georgiev IS, Gorman J, Joyce MG, O'Dell S, Zhou T, McDermott AB, Mascola JR, Kwong PD
(2017) J Virol 91: - Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin.
Potet F, Chagot B, Anghelescu M, Viswanathan PC, Stepanovic SZ, Kupershmidt S, Chazin WJ, Balser JR
(2009) J Biol Chem 284: 8846-54 - The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737.
Boiani M, Daniel C, Liu X, Hogarty MD, Marnett LJ
(2013) J Biol Chem 288: 6980-90 - Critical role of the central 139-loop in stability and binding selectivity of arrestin-1.
Vishnivetskiy SA, Baameur F, Findley KR, Gurevich VV
(2013) J Biol Chem 288: 11741-50 - Engineering visual arrestin-1 with special functional characteristics.
Vishnivetskiy SA, Chen Q, Palazzo MC, Brooks EK, Altenbach C, Iverson TM, Hubbell WL, Gurevich VV
(2013) J Biol Chem 288: 3394-405 - Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation.
Watkins GR, Wang N, Mazalouskas MD, Gomez RJ, Guthrie CR, Kraemer BC, Schweiger S, Spiller BW, Wadzinski BE
(2012) J Biol Chem 287: 24207-15 - Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating.
Lo WY, Lagrange AH, Hernandez CC, Harrison R, Dell A, Haslam SM, Sheehan JH, Macdonald RL
(2010) J Biol Chem 285: 31348-61 - The NC2 domain of type IX collagen determines the chain register of the triple helix.
Boudko SP, Bächinger HP
(2012) J Biol Chem 287: 44536-45 - Inhibition of thrombin formation by active site mutated (S360A) activated protein C.
Nicolaes GA, Bock PE, Segers K, Wildhagen KC, Dahlbäck B, Rosing J
(2010) J Biol Chem 285: 22890-900 - Kinetochore-microtubule stability governs the metaphase requirement for Eg5.
Gayek AS, Ohi R
(2014) Mol Biol Cell 25: 2051-60 - Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y
(2016) Genetics 203: 269-81 - Intracellular Degradation of Helicobacter pylori VacA Toxin as a Determinant of Gastric Epithelial Cell Viability.
Foegeding NJ, Raghunathan K, Campbell AM, Kim SW, Lau KS, Kenworthy AK, Cover TL, Ohi MD
(2019) Infect Immun 87: - Structure of hibiscus latent singapore virus by fiber diffraction: a nonconserved his122 contributes to coat protein stability.
Tewary SK, Oda T, Kendall A, Bian W, Stubbs G, Wong SM, Swaminathan K
(2011) J Mol Biol 406: 516-26 - The anaphase promoting complex contributes to the degradation of the S. cerevisiae telomerase recruitment subunit Est1p.
Ferguson JL, Chao WC, Lee E, Friedman KL
(2013) PLoS One 8: e55055 - ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes.
Smith AL, Friedman DB, Yu H, Carnahan RH, Reynolds AB
(2011) PLoS One 6: e16206 - The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling.
Sethman CR, Hawiger J
(2013) PLoS One 8: e70994 - Octarellin VI: using rosetta to design a putative artificial (β/α)8 protein.
Figueroa M, Oliveira N, Lejeune A, Kaufmann KW, Dorr BM, Matagne A, Martial JA, Meiler J, Van de Weerdt C
(2013) PLoS One 8: e71858 - Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.
Nifoussi SK, Vrana JA, Domina AM, De Biasio A, Gui J, Gregory MA, Hann SR, Craig RW
(2012) PLoS One 7: e47060 - The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi.
Lohia M, Qin Y, Macara IG
(2012) PLoS One 7: e51130
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