Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. DeBaun MR, Gordon M, McKinstry RC, Noetzel MJ, White DA, Sarnaik SA, Meier ER, Howard TH, Majumdar S, Inusa BP, Telfer PT, Kirby-Allen M, McCavit TL, Kamdem A, Airewele G, Woods GM, Berman B, Panepinto JA, Fuh BR, Kwiatkowski JL, King AA, Fixler JM, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Dixon N, Gonzalez CE, Kalinyak KA, Quinn CT, Strouse JJ, Miller JP, Lehmann H, Kraut MA, Ball WS, Hirtz D, Casella JF (2014) N Engl J Med 371: 699-710 Sickle cell disease, vasculopathy, and therapeutics. Kassim AA, DeBaun MR (2013) Annu Rev Med 64: 451-66 Molecular aspects of sickle cell disease. Waterman MR, Cottam GL (1976) Angew Chem Int Ed Engl 15: 749-57 Sickle hemoglobin disturbs normal coupling among erythrocyte O2 content, glycolysis, and antioxidant capacity. Rogers SC, Ross JG, d'Avignon A, Gibbons LB, Gazit V, Hassan MN, McLaughlin D, Griffin S, Neumayr T, Debaun M, DeBaun MR, Doctor A (2013) Blood 121: 1651-62 Associated risk factors for silent cerebral infarcts in sickle cell anemia: low baseline hemoglobin, sex, and relative high systolic blood pressure. DeBaun MR, Sarnaik SA, Rodeghier MJ, Minniti CP, Howard TH, Iyer RV, Inusa B, Telfer PT, Kirby-Allen M, Quinn CT, Bernaudin F, Airewele G, Woods GM, Panepinto JA, Fuh B, Kwiatkowski JK, King AA, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Sabio H, Gonzalez CE, Saccente SL, Kalinyak KA, Strouse JJ, Fixler JM, Gordon MO, Miller JP, Noetzel MJ, Ichord RN, Casella JF (2012) Blood 119: 3684-90 Characterization of beta-globin haplotypes using blood spots from a population-based cohort of newborns with homozygous HbS. Crawford DC, Caggana M, Harris KB, Lorey F, Nash C, Pass KA, Tempelis C, Olney RS (2002) Genet Med 4: 328-35 Alteration of the trate of deoxyhemoglobin S polymerization. Effect of pH and percentage of oxygenation. Shibata K, Waterman MR, Cottam GL (1977) J Biol Chem 252: 7468-74 Effects of experimental asthma on inflammation and lung mechanics in sickle cell mice. Pritchard KA, Feroah TR, Nandedkar SD, Holzhauer SL, Hutchins W, Schulte ML, Strunk RC, Debaun MR, Hillery CA (2012) Am J Respir Cell Mol Biol 46: 389-96 Daytime pulse oximeter measurements do not predict incidence of pain and acute chest syndrome episodes in sickle cell anemia. Uong EC, Boyd JH, DeBaun MR (2006) J Pediatr 149: 707-9 Cerebral hemodynamics and metabolism are similar in sickle cell disease patients with hemoglobin SS and Sβ thalassemia phenotypes. Ikwuanusi I, Jordan LC, Lee CA, Patel NJ, Waddle S, Pruthi S, Davis LT, Griffin A, DeBaun MR, Kassim AA, Donahue MJ (2020) Am J Hematol 95: E66-E68 Inhibitory effect of deoxyhemoglobin A2 on the rate of deoxyhemoglobin S polymerization. Waterman MR, Cottam GL, Shibata K (1979) J Mol Biol 129: 337-41 Differential polarization imaging. III. Theory confirmation. Patterns of polymerization of hemoglobin S in red blood sickle cells. Beach DA, Bustamante C, Wells KS, Foucar KM (1988) Biophys J 53: 449-56 Differential polarization imaging. III. Theory confirmation. Patterns of polymerization of hemoglobin S in red blood sickle cells. Beach DA, Bustamante C, Wells KS, Foucar KM (1987) Biophys J 52: 947-54 Acceleration of the rate of deoxyhemoglobin S polymerization by the erythrocyte membrane. Shibata K, Cottam GL, Waterman MR (1980) FEBS Lett 110: 107-10 Effect of pH, carbamylation and other hemoglobins on deoxyhemoglobin S aggregation inside intact erythrocytes as detected by proton relaxation rate measurements. Chuang AH, Waterman MR, Yamaoka K, Cottam L (1975) Arch Biochem Biophys 167: 145-50 Kinetics of polymerization of deoxyhemoglobin S and mixtures of hemoglobin A and hemoglobin S at high hemoglobin concentrations. Cottam GL, Waterman MR, Thompson BC (1977) Arch Biochem Biophys 181: 61-5 Effect of oxygen concentration on trasverse water proton relaxation times in erythrocytes homozygous and heterozygous for hemoglonin S. Cottam GL, Waterman MR (1976) Arch Biochem Biophys 177: 293-8 Evaluation of the water environments in deoxygenated sickle cells by longitudinal and transverse water proton relaxation rates. Thompson BC, Waterman MR, Cottam GL (1975) Arch Biochem Biophys 166: 193-200 Discordance between self-report and genetic confirmation of sickle cell disease status in African-American adults. Bean CJ, Hooper WC, Ellingsen D, DeBaun MR, Sonderman J, Blot WJ (2014) Public Health Genomics 17: 169-72 Kinetics of the polymerization of hemoglobin S: studies below normal erythrocyte hemoglobin concentration. Waterman MR, Cottam GL (1976) Biochem Biophys Res Commun 73: 639-45 Reversible solubility of deoxyhemoglobin S. Cottam GL, Waterman MR (1973) Biochem Biophys Res Commun 54: 1157-63 Blood transfusion therapy is feasible in a clinical trial setting in children with sickle cell disease and silent cerebral infarcts. King AA, Noetzel M, White DA, McKinstry RC, Debaun MR (2008) Pediatr Blood Cancer 50: 599-602 Recent advances in polarization spectroscopy: perspectives of the extension to the soft X-ray region. Bustamante C, Maestre MF, Wells KS (1986) Photochem Photobiol 44: 331-41 Inhibitory control in children with frontal infarcts related to sickle cell disease. Christ SE, Moinuddin A, McKinstry RC, DeBaun M, White DA (2007) Child Neuropsychol 13: 132-41 The relationship of oxygen transport and cardiac index for the prevention of sickle cell crises. Farrell K, Dent L, Nguyen ML, Buchowski M, Bhatt A, Aguinaga Mdel P (2010) J Natl Med Assoc 102: 1000-7
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.