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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Leucine are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Leucine.
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- Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
Yamagata K, Furuta H, Oda N, Kaisaki PJ, Menzel S, Cox NJ, Fajans SS, Signorini S, Stoffel M, Bell GI
(1996) Nature 384: 458-60 - Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1.
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM
(2001) Nature 413: 131-8 - Control of pancreas and liver gene expression by HNF transcription factors.
Odom DT, Zizlsperger N, Gordon DB, Bell GW, Rinaldi NJ, Murray HL, Volkert TL, Schreiber J, Rolfe PA, Gifford DK, Fraenkel E, Bell GI, Young RA
(2004) Science 303: 1378-81 - A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter.
Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, Zeleznik-Le NJ, Ting JP, Glimcher LH
(1990) Science 247: 1581-4 - Isotope-edited NMR of cyclosporin A bound to cyclophilin: evidence for a trans 9,10 amide bond.
Fesik SW, Gampe RT, Holzman TF, Egan DA, Edalji R, Luly JR, Simmer R, Helfrich R, Kishore V, Rich DH
(1990) Science 250: 1406-9 - TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
Nakagawa Y, Shimano H, Yoshikawa T, Ide T, Tamura M, Furusawa M, Yamamoto T, Inoue N, Matsuzaka T, Takahashi A, Hasty AH, Suzuki H, Sone H, Toyoshima H, Yahagi N, Yamada N
(2006) Nat Med 12: 107-13 - The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB
(2003) Nat Med 9: 220-4 - Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain.
Flick K, Ouni I, Wohlschlegel JA, Capati C, McDonald WH, Yates JR, Kaiser P
(2004) Nat Cell Biol 6: 634-41 - Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain.
Fremeau RT, Caron MG, Blakely RD
(1992) Neuron 8: 915-26 - Getting the message across: a recent transporter structure shows the way.
Henry LK, DeFelice LJ, Blakely RD
(2006) Neuron 49: 791-6 - SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion.
Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD
(2017) Cell Metab 25: 838-855.e15 - Identification of Susceptibility Loci and Genes for Colorectal Cancer Risk.
Zeng C, Matsuda K, Jia WH, Chang J, Kweon SS, Xiang YB, Shin A, Jee SH, Kim DH, Zhang B, Cai Q, Guo X, Long J, Wang N, Courtney R, Pan ZZ, Wu C, Takahashi A, Shin MH, Matsuo K, Matsuda F, Gao YT, Oh JH, Kim S, Jung KJ, Ahn YO, Ren Z, Li HL, Wu J, Shi J, Wen W, Yang G, Li B, Ji BT, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO), Brenner H, Schoen RE, Küry S, Colorectal Transdisciplinary (CORECT) Study, Gruber SB, Schumacher FR, Stenzel SL, Colon Cancer Family Registry (CCFR), Casey G, Hopper JL, Jenkins MA, Kim HR, Jeong JY, Park JW, Tajima K, Cho SH, Kubo M, Shu XO, Lin D, Zeng YX, Zheng W
(2016) Gastroenterology 150: 1633-1645 - Role of insulin in the regulation of leucine kinetics in the conscious dog.
Abumrad NN, Jefferson LS, Rannels SR, Williams PE, Cherrington AD, Lacy WW
(1982) J Clin Invest 70: 1031-41 - Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients.
Pupim LB, Flakoll PJ, Brouillette JR, Levenhagen DK, Hakim RM, Ikizler TA
(2002) J Clin Invest 110: 483-92 - Hepatic glucose sensing: does flux matter?
Shiota M, Magnuson MA
(2008) J Clin Invest 118: 841-4 - The alternatively initiated c-Myc proteins differentially regulate transcription through a noncanonical DNA-binding site.
Hann SR, Dixit M, Sears RC, Sealy L
(1994) Genes Dev 8: 2441-52 - A murine homolog of the yeast RNA1 gene is required for postimplantation development.
DeGregori J, Russ A, von Melchner H, Rayburn H, Priyaranjan P, Jenkins NA, Copeland NG, Ruley HE
(1994) Genes Dev 8: 265-76 - Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes.
Pimentel DR, Amin JK, Xiao L, Miller T, Viereck J, Oliver-Krasinski J, Baliga R, Wang J, Siwik DA, Singh K, Pagano P, Colucci WS, Sawyer DB
(2001) Circ Res 89: 453-60 - Superoxide reaction with tyrosyl radicals generates para-hydroperoxy and para-hydroxy derivatives of tyrosine.
Möller MN, Hatch DM, Kim HY, Porter NA
(2012) J Am Chem Soc 134: 16773-80 - CaV1.2 beta-subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations.
Koval OM, Guan X, Wu Y, Joiner ML, Gao Z, Chen B, Grumbach IM, Luczak ED, Colbran RJ, Song LS, Hund TJ, Mohler PJ, Anderson ME
(2010) Proc Natl Acad Sci U S A 107: 4996-5000 - Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver.
Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K
(2003) Proc Natl Acad Sci U S A 100: 5107-12 - Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10.
Engler DB, Reuter S, van Wijck Y, Urban S, Kyburz A, Maxeiner J, Martin H, Yogev N, Waisman A, Gerhard M, Cover TL, Taube C, Müller A
(2014) Proc Natl Acad Sci U S A 111: 11810-5 - Nutritional supplementation acutely increases albumin fractional synthetic rate in chronic hemodialysis patients.
Pupim LB, Flakoll PJ, Ikizler TA
(2004) J Am Soc Nephrol 15: 1920-6 - The MYC-WDR5 Nexus and Cancer.
Thomas LR, Foshage AM, Weissmiller AM, Tansey WP
(2015) Cancer Res 75: 4012-5 - Cre reconstitution allows for DNA recombination selectively in dual-marker-expressing cells in transgenic mice.
Xu Y, Xu G, Liu B, Gu G
(2007) Nucleic Acids Res 35: e126 - Calpains play a role in insulin secretion and action.
Sreenan SK, Zhou YP, Otani K, Hansen PA, Currie KP, Pan CY, Lee JP, Ostrega DM, Pugh W, Horikawa Y, Cox NJ, Hanis CL, Burant CF, Fox AP, Bell GI, Polonsky KS
(2001) Diabetes 50: 2013-20 - Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes.
Schepeler T, Holm A, Halvey P, Nordentoft I, Lamy P, Riising EM, Christensen LL, Thorsen K, Liebler DC, Helin K, Ørntoft TF, Andersen CL
(2012) Oncogene 31: 2750-60 - A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.
Zhang X, Garbett K, Veeraraghavalu K, Wilburn B, Gilmore R, Mirnics K, Sisodia SS
(2012) J Neurosci 32: 8633-48 - No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
Hara M, Wang X, Paz VP, Cox NJ, Iwasaki N, Ogata M, Iwamoto Y, Bell GI
(2000) Diabetologia 43: 1064-9 - Pseudomonas-induced neutrophil recruitment in the dog airway in vivo is mediated in part by IL-8 and inhibited by a leumedin.
Jorens PG, Richman-Eisenstat JB, Housset BP, Massion PP, Ueki I, Nadel JA
(1994) Eur Respir J 7: 1925-31 - Investigation of the Complete Suite of the Leucine and Isoleucine Isomers: Toward Prediction of Ion Mobility Separation Capabilities.
Dodds JN, May JC, McLean JA
(2017) Anal Chem 89: 952-959 - Ablation of leptin receptor-mediated ERK activation impairs host defense against Gram-negative pneumonia.
Mancuso P, Myers MG, Goel D, Serezani CH, O'Brien E, Goldberg J, Aronoff DM, Peters-Golden M
(2012) J Immunol 189: 867-75 - Fragments of ATM which have dominant-negative or complementing activity.
Morgan SE, Lovly C, Pandita TK, Shiloh Y, Kastan MB
(1997) Mol Cell Biol 17: 2020-9 - Regulation of the cfos serum response element by C/EBPbeta.
Sealy L, Malone D, Pawlak M
(1997) Mol Cell Biol 17: 1744-55 - pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167.
Joel PB, Smith J, Sturgill TW, Fisher TL, Blenis J, Lannigan DA
(1998) Mol Cell Biol 18: 1978-84 - Variant Max protein, derived by alternative splicing, associates with c-Myc in vivo and inhibits transactivation.
Arsura M, Deshpande A, Hann SR, Sonenshein GE
(1995) Mol Cell Biol 15: 6702-9 - The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.
Zhang P, McGrath BC, Reinert J, Olsen DS, Lei L, Gill S, Wek SA, Vattem KM, Wek RC, Kimball SR, Jefferson LS, Cavener DR
(2002) Mol Cell Biol 22: 6681-8 - Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.
Sekhar KR, Spitz DR, Harris S, Nguyen TT, Meredith MJ, Holt JT, Gius D, Marnett LJ, Summar ML, Freeman ML, Guis D
(2002) Free Radic Biol Med 32: 650-62
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