Inhibition of nuclear hormone receptor activity by calreticulin. Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ (1994) Nature 367: 480-3 An RNA-export mediator with an essential nuclear export signal. Murphy R, Wente SR (1996) Nature 383: 357-60 Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA (2013) Cell 155: 1624-38 Uncovering nuclear pore complexity with innovation. Adams RL, Wente SR (2013) Cell 152: 1218-21 Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA. Saitoh S, Chabes A, McDonald WH, Thelander L, Yates JR, Russell P (2002) Cell 109: 563-73 SnapShot: nuclear transport. Tran EJ, Bolger TA, Wente SR (2007) Cell 131: 420 Dynamic nuclear pore complexes: life on the edge. Tran EJ, Wente SR (2006) Cell 125: 1041-53 Gle1 functions during mRNA export in an oligomeric complex that is altered in human disease. Folkmann AW, Collier SE, Zhan X, Aditi , Ohi MD, Wente SR (2013) Cell 155: 582-93 Gatekeepers of the nucleus. Wente SR (2000) Science 288: 1374-7 Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75. Carter BD, Kaltschmidt C, Kaltschmidt B, Offenhäuser N, Böhm-Matthaei R, Baeuerle PA, Barde YA (1996) Science 272: 542-5 Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport. Terry LJ, Shows EB, Wente SR (2007) Science 318: 1412-6 A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. Odom AR, Stahlberg A, Wente SR, York JD (2000) Science 287: 2026-9 In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. Gargiulo G, Cesaroni M, Serresi M, de Vries N, Hulsman D, Bruggeman SW, Lancini C, van Lohuizen M (2013) Cancer Cell 23: 660-76 PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL (2002) Nat Med 8: 1145-52 Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export. Alcázar-Román AR, Tran EJ, Guo S, Wente SR (2006) Nat Cell Biol 8: 711-6 Nuclear mRNA on the move. Noble KN, Wente SR (2010) Nat Cell Biol 12: 525-7 Minimal nuclear pore complexes define FG repeat domains essential for transport. Strawn LA, Shen T, Shulga N, Goldfarb DS, Wente SR (2004) Nat Cell Biol 6: 197-206 Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Kenchappa RS, Zampieri N, Chao MV, Barker PA, Teng HK, Hempstead BL, Carter BD (2006) Neuron 50: 219-32 The DEAD-box protein Dbp5 controls mRNA export by triggering specific RNA:protein remodeling events. Tran EJ, Zhou Y, Corbett AH, Wente SR (2007) Mol Cell 28: 850-9 Evidence for inflammatory signaling in idiopathic pulmonary artery hypertension: TRPC6 and nuclear factor-kappaB. Hamid R, Newman JH (2009) Circulation 119: 2297-8 Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F (2016) Cell Metab 23: 837-51 Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders. Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, King R, Cohen DJ, Gore JC, Lombroso P (2000) Arch Gen Psychiatry 57: 364-72 Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia. Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M (2012) J Exp Med 209: 713-28 T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent. Zhang F, Boothby M (2006) J Exp Med 203: 1493-505 Peering through the pore: nuclear pore complex structure, assembly, and function. Suntharalingam M, Wente SR (2003) Dev Cell 4: 775-89 Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. Yan F, John SK, Wilson G, Jones DS, Washington MK, Polk DB (2004) J Clin Invest 114: 1272-80 The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. Kitamura T, Nakae J, Kitamura Y, Kido Y, Biggs WH, Wright CV, White MF, Arden KC, Accili D (2002) J Clin Invest 110: 1839-47 The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1. Noble KN, Tran EJ, Alcázar-Román AR, Hodge CA, Cole CN, Wente SR (2011) Genes Dev 25: 1065-77 BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J (2000) Genes Dev 14: 927-39 Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT (2000) Genes Dev 14: 2989-3002 The Dbp5 cycle at the nuclear pore complex during mRNA export I: dbp5 mutants with defects in RNA binding and ATP hydrolysis define key steps for Nup159 and Gle1. Hodge CA, Tran EJ, Noble KN, Alcazar-Roman AR, Ben-Yishay R, Scarcelli JJ, Folkmann AW, Shav-Tal Y, Wente SR, Cole CN (2011) Genes Dev 25: 1052-64 The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis. Lee DK, Park SH, Yi Y, Choi SG, Lee C, Parks WT, Cho H, de Caestecker MP, Shaul Y, Roberts AB, Kim SJ (2001) Genes Dev 15: 455-66 Postage for the messenger: designating routes for nuclear mRNA export. Natalizio BJ, Wente SR (2013) Trends Cell Biol 23: 365-73 The nuclear pore complex: a protein machine bridging the nucleus and cytoplasm. Ryan KJ, Wente SR (2000) Curr Opin Cell Biol 12: 361-71 Trafficking to uncharted territory of the nuclear envelope. Burns LT, Wente SR (2012) Curr Opin Cell Biol 24: 341-9
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.