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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Publications
- Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.
Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C
(2002) Nature 418: 979-83 - Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.
Veeriah S, Taylor BS, Meng S, Fang F, Yilmaz E, Vivanco I, Janakiraman M, Schultz N, Hanrahan AJ, Pao W, Ladanyi M, Sander C, Heguy A, Holland EC, Paty PB, Mischel PS, Liau L, Cloughesy TF, Mellinghoff IK, Solit DB, Chan TA
(2010) Nat Genet 42: 77-82 - Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus.
Karimy JK, Zhang J, Kurland DB, Theriault BC, Duran D, Stokum JA, Furey CG, Zhou X, Mansuri MS, Montejo J, Vera A, DiLuna ML, Delpire E, Alper SL, Gunel M, Gerzanich V, Medzhitov R, Simard JM, Kahle KT
(2017) Nat Med 23: 997-1003 - Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.
Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW
(2016) Nat Med 22: 800-6 - Extracellular rigidity sensing by talin isoform-specific mechanical linkages.
Austen K, Ringer P, Mehlich A, Chrostek-Grashoff A, Kluger C, Klingner C, Sabass B, Zent R, Rief M, Grashoff C
(2015) Nat Cell Biol 17: 1597-606 - A dermal niche for multipotent adult skin-derived precursor cells.
Fernandes KJ, McKenzie IA, Mill P, Smith KM, Akhavan M, Barnabé-Heider F, Biernaskie J, Junek A, Kobayashi NR, Toma JG, Kaplan DR, Labosky PA, Rafuse V, Hui CC, Miller FD
(2004) Nat Cell Biol 6: 1082-93 - Osteopontin as a mediator of NKT cell function in T cell-mediated liver diseases.
Diao H, Kon S, Iwabuchi K, Kimura C, Morimoto J, Ito D, Segawa T, Maeda M, Hamuro J, Nakayama T, Taniguchi M, Yagita H, Van Kaer L, Onóe K, Denhardt D, Rittling S, Uede T
(2004) Immunity 21: 539-50 - Light-dependent redistribution of arrestin in vertebrate rods is an energy-independent process governed by protein-protein interactions.
Nair KS, Hanson SM, Mendez A, Gurevich EV, Kennedy MJ, Shestopalov VI, Vishnivetskiy SA, Chen J, Hurley JB, Gurevich VV, Slepak VZ
(2005) Neuron 46: 555-67 - Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Romero-Hernandez A, Simorowski N, Karakas E, Furukawa H
(2016) Neuron 92: 1324-1336 - Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons.
Kenchappa RS, Zampieri N, Chao MV, Barker PA, Teng HK, Hempstead BL, Carter BD
(2006) Neuron 50: 219-32 - Rap1 couples cAMP signaling to a distinct pool of p42/44MAPK regulating excitability, synaptic plasticity, learning, and memory.
Morozov A, Muzzio IA, Bourtchouladze R, Van-Strien N, Lapidus K, Yin D, Winder DG, Adams JP, Sweatt JD, Kandel ER
(2003) Neuron 39: 309-25 - Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport.
Fog JU, Khoshbouei H, Holy M, Owens WA, Vaegter CB, Sen N, Nikandrova Y, Bowton E, McMahon DG, Colbran RJ, Daws LC, Sitte HH, Javitch JA, Galli A, Gether U
(2006) Neuron 51: 417-29 - HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.
Kile AC, Chavez DA, Bacal J, Eldirany S, Korzhnev DM, Bezsonova I, Eichman BF, Cimprich KA
(2015) Mol Cell 58: 1090-100 - Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice.
Zhang W, Yancey PG, Su YR, Babaev VR, Zhang Y, Fazio S, Linton MF
(2003) Circulation 108: 2258-63 - Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.
Baumgartl J, Baudler S, Scherner M, Babaev V, Makowski L, Suttles J, McDuffie M, Tobe K, Kadowaki T, Fazio S, Kahn CR, Hotamisligil GS, Krone W, Linton M, Brüning JC
(2006) Cell Metab 3: 247-56 - Klf15 orchestrates circadian nitrogen homeostasis.
Jeyaraj D, Scheer FA, Ripperger JA, Haldar SM, Lu Y, Prosdocimo DA, Eapen SJ, Eapen BL, Cui Y, Mahabeleshwar GH, Lee HG, Smith MA, Casadesus G, Mintz EM, Sun H, Wang Y, Ramsey KM, Bass J, Shea SA, Albrecht U, Jain MK
(2012) Cell Metab 15: 311-23 - Use of the probasin promoter ARR2PB to express Bax in androgen receptor-positive prostate cancer cells.
Andriani F, Nan B, Yu J, Li X, Weigel NL, McPhaul MJ, Kasper S, Kagawa S, Fang B, Matusik RJ, Denner L, Marcelli M
(2001) J Natl Cancer Inst 93: 1314-24 - Effects of cancer-associated EPHA3 mutations on lung cancer.
Zhuang G, Song W, Amato K, Hwang Y, Lee K, Boothby M, Ye F, Guo Y, Shyr Y, Lin L, Carbone DP, Brantley-Sieders DM, Chen J
(2012) J Natl Cancer Inst 104: 1182-97 - Constitutively active K-cyclin/cdk6 kinase in Kaposi sarcoma-associated herpesvirus-infected cells.
Van Dross R, Yao S, Asad S, Westlake G, Mays DJ, Barquero L, Duell S, Pietenpol JA, Browning PJ
(2005) J Natl Cancer Inst 97: 656-66 - E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas.
Tamura G, Yin J, Wang S, Fleisher AS, Zou T, Abraham JM, Kong D, Smolinski KN, Wilson KT, James SP, Silverberg SG, Nishizuka S, Terashima M, Motoyama T, Meltzer SJ
(2000) J Natl Cancer Inst 92: 569-73 - MT2-MMP-dependent release of collagen IV NC1 domains regulates submandibular gland branching morphogenesis.
Rebustini IT, Myers C, Lassiter KS, Surmak A, Szabova L, Holmbeck K, Pedchenko V, Hudson BG, Hoffman MP
(2009) Dev Cell 17: 482-93 - ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.
Lee Y, Fryer JD, Kang H, Crespo-Barreto J, Bowman AB, Gao Y, Kahle JJ, Hong JS, Kheradmand F, Orr HT, Finegold MJ, Zoghbi HY
(2011) Dev Cell 21: 746-57 - Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/enhancer-binding proteins.
Callejas NA, Boscá L, Williams CS, DuBOIS RN, Martín-Sanz P
(2000) Gastroenterology 119: 493-501 - Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB.
Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M, Polk DB
(2008) Gastroenterology 135: 539-51 - Elevated cyclooxygenase-2 levels in Min mouse adenomas.
Williams CS, Luongo C, Radhika A, Zhang T, Lamps LW, Nanney LB, Beauchamp RD, DuBois RN
(1996) Gastroenterology 111: 1134-40 - N-methyl D-aspartate channels link ammonia and epithelial cell death mechanisms in Helicobacter pylori Infection.
Seo JH, Fox JG, Peek RM, Hagen SJ
(2011) Gastroenterology 141: 2064-75 - Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction.
Harris RC, McKanna JA, Akai Y, Jacobson HR, Dubois RN, Breyer MD
(1994) J Clin Invest 94: 2504-10 - Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption.
Haro H, Crawford HC, Fingleton B, MacDougall JR, Shinomiya K, Spengler DM, Matrisian LM
(2000) J Clin Invest 105: 133-41 - Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells.
Crossno JT, Majka SM, Grazia T, Gill RG, Klemm DJ
(2006) J Clin Invest 116: 3220-8 - Host cyclooxygenase-2 modulates carcinoma growth.
Williams CS, Tsujii M, Reese J, Dey SK, DuBois RN
(2000) J Clin Invest 105: 1589-94 - Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.
Sheng H, Shao J, Kirkland SC, Isakson P, Coffey RJ, Morrow J, Beauchamp RD, DuBois RN
(1997) J Clin Invest 99: 2254-9 - Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation.
Yan F, John SK, Wilson G, Jones DS, Washington MK, Polk DB
(2004) J Clin Invest 114: 1272-80 - LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function.
Holmstrom SR, Deering T, Swift GH, Poelwijk FJ, Mangelsdorf DJ, Kliewer SA, MacDonald RJ
(2011) Genes Dev 25: 1674-9 - Oncostatin M causes eotaxin-1 release from airway smooth muscle: synergy with IL-4 and IL-13.
Faffe DS, Flynt L, Mellema M, Moore PE, Silverman ES, Subramaniam V, Jones MR, Mizgerd JP, Whitehead T, Imrich A, Panettieri RA, Shore SA
(2005) J Allergy Clin Immunol 115: 514-20 - Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis.
Paik DT, Rai M, Ryzhov S, Sanders LN, Aisagbonhi O, Funke MJ, Feoktistov I, Hatzopoulos AK
(2015) Circ Res 117: 804-16 - Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.
Guo T, Cornea RL, Huke S, Camors E, Yang Y, Picht E, Fruen BR, Bers DM
(2010) Circ Res 106: 1743-52 - GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.
Li L, Rezvan A, Salerno JC, Husain A, Kwon K, Jo H, Harrison DG, Chen W
(2010) Circ Res 106: 328-36 - Assessing the functional characteristics of synonymous and nonsynonymous mutation candidates by use of large DNA constructs.
Eeds AM, Mortlock D, Wade-Martins R, Summar ML
(2007) Am J Hum Genet 80: 740-50 - Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model.
Wong M, Ess KC, Uhlmann EJ, Jansen LA, Li W, Crino PB, Mennerick S, Yamada KA, Gutmann DH
(2003) Ann Neurol 54: 251-6 - Chlamydia pneumoniae infection of the central nervous system in multiple sclerosis.
Sriram S, Stratton CW, Yao S, Tharp A, Ding L, Bannan JD, Mitchell WM
(1999) Ann Neurol 46: 6-14
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