Resistin, adiponectin, and risk of heart failure the Framingham offspring study. Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB (2009) J Am Coll Cardiol 53: 754-62 Rosiglitazone promotes development of a novel adipocyte population from bone marrow-derived circulating progenitor cells. Crossno JT, Majka SM, Grazia T, Gill RG, Klemm DJ (2006) J Clin Invest 116: 3220-8 Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1. Ma LJ, Mao SL, Taylor KL, Kanjanabuch T, Guan Y, Zhang Y, Brown NJ, Swift LL, McGuinness OP, Wasserman DH, Vaughan DE, Fogo AB (2004) Diabetes 53: 336-46 Diet-induced increases in adiposity, but not plasma lipids, promote macrophage infiltration into white adipose tissue. Coenen KR, Gruen ML, Chait A, Hasty AH (2007) Diabetes 56: 564-73 Molecular pathways: adiponectin and leptin signaling in cancer. Vansaun MN (2013) Clin Cancer Res 19: 1926-32 A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2. Wu Y, Gao H, Li H, Tabara Y, Nakatochi M, Chiu YF, Park EJ, Wen W, Adair LS, Borja JB, Cai Q, Chang YC, Chen P, Croteau-Chonka DC, Fogarty MP, Gan W, He CT, Hsiung CA, Hwu CM, Ichihara S, Igase M, Jo J, Kato N, Kawamoto R, Kuzawa CW, Lee JJ, Liu J, Lu L, McDade TW, Osawa H, Sheu WH, Teo Y, Vadlamudi S, Van Dam RM, Wang Y, Xiang YB, Yamamoto K, Ye X, Young TL, Zheng W, Zhu J, Shu XO, Shin C, Jee SH, Chuang LM, Miki T, Yokota M, Lin X, Mohlke KL, Tai ES (2014) Hum Mol Genet 23: 1108-19 Maternal and cord blood hormone levels in the United States and China and the intrauterine origin of breast cancer. Lagiou P, Samoli E, Okulicz W, Xu B, Lagiou A, Lipworth L, Georgila C, Vatten L, Adami HO, Trichopoulos D, Hsieh CC (2011) Ann Oncol 22: 1102-8 Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance. Ferguson JF, Phillips CM, Tierney AC, Pérez-Martínez P, Defoort C, Helal O, Lairon D, Planells R, Shaw DI, Lovegrove JA, Gjelstad IM, Drevon CA, Blaak EE, Saris WH, Leszczynska-Golabek I, Kiec-Wilk B, Risérus U, Karlström B, Miranda JL, Roche HM (2010) Am J Clin Nutr 91: 794-801 Body mass index and fat mass are the primary correlates of insulin resistance in nondiabetic stage 3-4 chronic kidney disease patients. Trirogoff ML, Shintani A, Himmelfarb J, Ikizler TA (2007) Am J Clin Nutr 86: 1642-8 Aldosterone deficiency prevents high-fat-feeding-induced hyperglycaemia and adipocyte dysfunction in mice. Luo P, Dematteo A, Wang Z, Zhu L, Wang A, Kim HS, Pozzi A, Stafford JM, Luther JM (2013) Diabetologia 56: 901-10 Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the African American-Diabetes Heart Study. Register TC, Divers J, Bowden DW, Carr JJ, Lenchik L, Wagenknecht LE, Hightower RC, Xu J, Smith SC, Hruska KA, Langefeld CD, Freedman BI (2013) J Clin Endocrinol Metab 98: 1916-22 Serum level of adiponectin and the risk of liver cancer development in chronic hepatitis C patients. Arano T, Nakagawa H, Tateishi R, Ikeda H, Uchino K, Enooku K, Goto E, Masuzaki R, Asaoka Y, Kondo Y, Goto T, Shiina S, Omata M, Yoshida H, Koike K (2011) Int J Cancer 129: 2226-35 Genetic polymorphisms in obesity-related genes and endometrial cancer risk. Chen X, Xiang YB, Long JR, Cai H, Cai Q, Cheng J, Wen W, Gao YT, Zheng W, Shu XO (2012) Cancer 118: 3356-64 One generation's "junk" is another's treasure: the emerging role of microRNAs as therapeutic targets. Brittain EL, Hemnes AR (2014) J Heart Lung Transplant 33: 233-4 HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genes. Edwards TL, Velez Edwards DR, Villegas R, Cohen SS, Buchowski MS, Fowke JH, Schlundt D, Long J, Long JR, Cai Q, Zheng W, Shu XO, Hargreaves MK, Smith J, Jeffrey S, Williams SM, Signorello LB, Blot WJ, Matthews CE (2012) Am J Epidemiol 175: 11-21 Empirical characteristics of family-based linkage to a complex trait: the ADIPOQ region and adiponectin levels. Hellwege JN, Palmer ND, Mark Brown W, Brown MW, Ziegler JT, Sandy An S, An SS, Guo X, Ida Chen YD, Chen IY, Taylor K, Hawkins GA, Ng MC, Speliotes EK, Lorenzo C, Norris JM, Rotter JI, Wagenknecht LE, Langefeld CD, Bowden DW (2015) Hum Genet 134: 203-13 The role of adipose tissue in mediating the beneficial effects of dietary fish oil. Puglisi MJ, Hasty AH, Saraswathi V (2011) J Nutr Biochem 22: 101-8 Plasminogen activator inhibitor-1 modulates adipocyte differentiation. Liang X, Kanjanabuch T, Mao SL, Hao CM, Tang YW, Declerck PJ, Hasty AH, Wasserman DH, Fogo AB, Ma LJ (2006) Am J Physiol Endocrinol Metab 290: E103-E113 Adipose tissue density, a novel biomarker predicting mortality risk in older adults. Murphy RA, Register TC, Shively CA, Carr JJ, Ge Y, Heilbrun ME, Cummings SR, Koster A, Nevitt MC, Satterfield S, Tylvasky FA, Strotmeyer ES, Newman AB, Simonsick EM, Scherzinger A, Goodpaster BH, Launer LJ, Eiriksdottir G, Sigurdsson S, Sigurdsson G, Gudnason V, Lang TF, Kritchevsky SB, Harris TB (2014) J Gerontol A Biol Sci Med Sci 69: 109-17 Fish oil increases cholesterol storage in white adipose tissue with concomitant decreases in inflammation, hepatic steatosis, and atherosclerosis in mice. Saraswathi V, Gao L, Morrow JD, Chait A, Niswender KD, Hasty AH (2007) J Nutr 137: 1776-82 Emerging role of AMP-activated protein kinase in endocrine control of metabolism in the liver. Hasenour CM, Berglund ED, Wasserman DH (2013) Mol Cell Endocrinol 366: 152-62 Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Aslibekyan S, An P, Frazier-Wood AC, Kabagambe EK, Irvin MR, Straka RJ, Tiwari HK, Tsai MY, Hopkins PN, Borecki IB, Ordovas JM, Arnett DK (2013) Nutr Metab Cardiovasc Dis 23: 987-94 ADIPOQ, ADIPOR1, and ADIPOR2 polymorphisms in relation to serum adiponectin levels and BMI in black and white women. Cohen SS, Gammon MD, North KE, Millikan RC, Lange EM, Williams SM, Zheng W, Cai Q, Long J, Smith JR, Signorello LB, Blot WJ, Matthews CE (2011) Obesity (Silver Spring) 19: 2053-62 Variants in adiponectin signaling pathway genes show little association with subclinical CVD in the diabetes heart study. Cox AJ, Lambird JE, An SS, Register TC, Langefeld CD, Carr JJ, Freedman BI, Bowden DW (2013) Obesity (Silver Spring) 21: E456-62 Modulation of adipocyte biology by δ(9)-tetrahydrocannabinol. Teixeira D, Pestana D, Faria A, Calhau C, Azevedo I, Monteiro R (2010) Obesity (Silver Spring) 18: 2077-85 ADIPOQ polymorphisms, monounsaturated fatty acids, and obesity risk: the GOLDN study. Warodomwichit D, Shen J, Arnett DK, Tsai MY, Kabagambe EK, Peacock JM, Hixson JE, Straka RJ, Province MA, An P, Lai CQ, Parnell LD, Borecki IB, Ordovas JM (2009) Obesity (Silver Spring) 17: 510-7 Insulin-independent role of adiponectin receptor signaling in Drosophila germline stem cell maintenance. Laws KM, Sampson LL, Drummond-Barbosa D (2015) Dev Biol 399: 226-36 The role of inflammatory pathway genetic variation on maternal metabolic phenotypes during pregnancy. Urbanek M, Hayes MG, Lee H, Freathy RM, Lowe LP, Ackerman C, Jafari N, Dyer AR, Cox NJ, Dunger DB, Hattersley AT, Metzger BE, Lowe WL (2012) PLoS One 7: e32958 Chronic ethanol-induced insulin resistance is associated with macrophage infiltration into adipose tissue and altered expression of adipocytokines. Kang L, Sebastian BM, Pritchard MT, Pratt BT, Previs SF, Nagy LE (2007) Alcohol Clin Exp Res 31: 1581-8 Glycemic load is associated with oxidative stress among prevalent maintenance hemodialysis patients. Limkunakul C, Sundell MB, Pouliot B, Graves AJ, Shintani A, Ikizler TA (2014) Nephrol Dial Transplant 29: 1047-53 Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice. Saraswathi V, Ramnanan CJ, Wilks AW, Desouza CV, Eller AA, Murali G, Ramalingam R, Milne GL, Coate KC, Edgerton DS (2013) Metabolism 62: 1673-85 Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice. Satoh M, Hoshino M, Fujita K, Iizuka M, Fujii S, Clingan CS, Van Kaer L, Iwabuchi K (2016) Sci Rep 6: 28473 Association between prostate-specific antigen and leptin, adiponectin, HbA1c or C-peptide among African-American and Caucasian men. Fowke JH, Matthews CM, Buchowski MS, Signorello LB, Chang SS, Cookson MS, Blot WJ (2008) Prostate Cancer Prostatic Dis 11: 264-9 Serum CRP levels are equally elevated in newly diagnosed type 2 diabetes and impaired glucose tolerance and related to adiponectin levels and insulin sensitivity. Yuan G, Zhou L, Tang J, Yang Y, Gu W, Li F, Hong J, Gu Y, Li X, Ning G, Chen M (2006) Diabetes Res Clin Pract 72: 244-50 Serum leptin level mediates the association of body composition and serum C-reactive protein in HIV-infected persons on antiretroviral therapy. Koethe JR, Bian A, Shintani AK, Boger MS, Mitchell VJ, Erdem H, Hulgan T (2012) AIDS Res Hum Retroviruses 28: 552-7
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.