Non-rigid Registration of Serial Intra-operative Images for Automatic Brain Shift Estimation.

Duay V, Sinha TK, D'Haese PF, Miga MI, Dawant BM
Biomed Image Registration. 2003 2717: 61-70

PMID: 26069890 · PMCID: PMC4460989 · DOI:10.1007/978-3-540-39701-4_7

Measurement of intra-operative brain motion is important to provide boundary conditions to physics-based deformation models that can be used to register pre- and intra-operative information. In this paper we present and test a technique that can be used to measure brain surface motion automatically. This method relies on a tracked laser range scanner (LRS) that can acquire simultaneously a picture and the 3D physical coordinates of objects within its field of view. This reduces the 3D tracking problem to a 2D non-rigid registration problem which we solve with a Mutual Information-based algorithm. Results obtained on images of a phantom and on images acquired intra-operatively that demonstrate the feasibility of the method are presented.

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