Prognostic significance of computed tomography in resected N2 lung cancer.

Cybulsky IJ, Lanza LA, Ryan MB, Putnam JB, McMurtrey MM, Roth JA
Ann Thorac Surg. 1992 54 (3): 533-7

PMID: 1324657 · DOI:10.1016/0003-4975(92)90449-e

We reviewed 124 patients from 1982 to 1988 who had a resected primary non-small cell lung cancer metastatic to mediastinal (N2) lymph nodes and a preoperative assessment of the mediastinum with computed tomography of the chest. Sixty-three patients studied had computed tomographic evidence of mediastinal lymph node enlargement. In these patients the survival at 5 years was only 6.6%, compared with the 5-year survival of 13.5% in 61 patients in whom the mediastinum was normal. Plain chest roentgenography with evidence of mediastinal adenopathy did not predict a poorer outcome. In addition, patients with tumors located in the left upper lobe were found to have an improved survival. These patients had a 5-year survival of 20.8%. Tumor histology, central location of the tumor, extranodal extension, and type of resection did not result in a significant survival difference.

MeSH Terms (14)

Adult Aged Aged, 80 and over Carcinoma, Non-Small-Cell Lung Female Humans Lung Neoplasms Lymphatic Metastasis Male Mediastinal Neoplasms Middle Aged Prognosis Survival Rate Tomography, X-Ray Computed

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