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Introduction to Metals in Biology 2017: Iron transport, storage, and the ramifications.

Guengerich FP
J Biol Chem. 2017 292 (31): 12725-12726

PMID: 28615455 · PMCID: PMC5546012 · DOI:10.1074/jbc.R117.801332

In this tenth Thematic Series in Metals in Biology, six Minireviews deal with aspects of iron metabolism. A number of important proteins control iron homeostasis, including hepcidin and ferroportin, in various cells. Other aspects of iron dealt with here include biogenesis of iron-sulfur proteins and chaperones that deliver iron cofactors in cells. Additionally, an iron-regulated metastasis suppressor interacts with the epidermal growth factor receptor and mediates its downstream signaling activity.

© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

MeSH Terms (7)

Animals Biological Transport Homeostasis Humans Iron Iron-Regulatory Proteins Iron-Sulfur Proteins

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