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Metals in Biology 2016: Molecular Basis of Selection of Metals by Enzymes.

Guengerich FP
J Biol Chem. 2016 291 (40): 20838-20839

PMID: 27462079 · PMCID: PMC5076496 · DOI:10.1074/jbc.R116.749259

This ninth Metals in Biology Thematic Series deals with the fundamental issue of why certain enzymes prefer individual metals. Why do some prefer sodium and some prefer potassium? Is it just the size? Why does calcium have so many regulatory functions? Why do some proteins have an affinity for zinc? How is the homeostasis of calcium and zinc achieved? How do enzymes discriminate between the similar metals magnesium and manganese? Four Minireviews address these and related questions about metal ion preferences in biological systems.

© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

MeSH Terms (3)

Enzymes Metalloproteins Metals

Connections (1)

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