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Formyl chloride has been indirectly implicated as an intermediate in the oxidation of CH(2)Cl(2) and proposed to be a product of the oxidation of some other compounds. Formyl chloride was synthesized and added to aqueous solutions, with CO formed as a product. The presence of glutathione (GSH) did not reduce the yield of CO at any of the pH values tested. At pH >or= 9, a small amount of S-formyl GSH was detected (
MeSH Terms (12)Animals Chromatography, Liquid Formates Glutathione Humans In Vitro Techniques Mass Spectrometry Methylene Chloride Microsomes, Liver Protein Binding Rats Rats, Sprague-Dawley
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Released July 13, 2020