Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.

Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS
J Clin Invest. 2021 131 (1)

PMID: 33108351 · PMCID: PMC7773387 · DOI:10.1172/JCI139481

MeSH Terms (9)

Animals Elastin Inflammation Leukocyte Elastase Mice Mice, Transgenic Neutrophils Pulmonary Alveoli Pulmonary Disease, Chronic Obstructive

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