TRP channels of the pancreatic beta cell.

Jacobson DA, Philipson LH
Handb Exp Pharmacol. 2007 (179): 409-24

PMID: 17217070 · DOI:10.1007/978-3-540-34891-7_24

Orchestrated ion fluctuations within pancreatic islets regulate hormone secretion and maybe essential to processes such as apoptosis. A diverse set of ion channels allows for islet cells to respond to a variety of signals and dynamically regulate hormone secretion and glucose homeostasis (reviewed by Houamed et al. 2004). This chapter focuses on transient receptor potential (TRP)-related channels found within the beta cells of the islet and reviews their roles in both insulin secretion and apoptosis.

MeSH Terms (6)

Animals Humans Insulin-Secreting Cells Ion Channels Neurosecretory Systems Transient Receptor Potential Channels

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