Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy.

Johnson DB, Estrada MV, Salgado R, Sanchez V, Doxie DB, Opalenik SR, Vilgelm AE, Feld E, Johnson AS, Greenplate AR, Sanders ME, Lovly CM, Frederick DT, Kelley MC, Richmond A, Irish JM, Shyr Y, Sullivan RJ, Puzanov I, Sosman JA, Balko JM
Nat Commun. 2016 7: 10582

PMID: 26822383 · PMCID: PMC4740184 · DOI:10.1038/ncomms10582

MeSH Terms (11)

Antibodies, Monoclonal Antibodies, Monoclonal, Humanized Cell Line, Tumor Gene Expression Regulation, Neoplastic Genes, MHC Class II Genotype Humans Melanoma Nivolumab Programmed Cell Death 1 Receptor RNA, Messenger

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