Dihydrothiazolopyridone derivatives as a novel family of positive allosteric modulators of the metabotropic glutamate 5 (mGlu5) receptor.

Bartolomé-Nebreda JM, Conde-Ceide S, Delgado F, Iturrino L, Pastor J, Pena MÁ, Trabanco AA, Tresadern G, Wassvik CM, Stauffer SR, Jadhav S, Gogi K, Vinson PN, Noetzel MJ, Days E, Weaver CD, Lindsley CW, Niswender CM, Jones CK, Conn PJ, Rombouts F, Lavreysen H, Macdonald GJ, Mackie C, Steckler T
J Med Chem. 2013 56 (18): 7243-59

PMID: 23947773 · PMCID: PMC3924858 · DOI:10.1021/jm400650w

MeSH Terms (12)

Allosteric Regulation Animals Antipsychotic Agents Behavior, Animal Dose-Response Relationship, Drug Humans Locomotion Male Rats Receptor, Metabotropic Glutamate 5 Structure-Activity Relationship Thiazoles

Connections (4)

This publication is referenced by other Labnodes entities:

Links