Discovery of ML326: The first sub-micromolar, selective M5 PAM.

Gentry PR, Bridges TM, Lamsal A, Vinson PN, Smith E, Chase P, Hodder PS, Engers JL, Niswender CM, Daniels JS, Conn PJ, Wood MR, Lindsley CW
Bioorg Med Chem Lett. 2013 23 (10): 2996-3000

PMID: 23562060 · PMCID: PMC3634896 · DOI:10.1016/j.bmcl.2013.03.032

MeSH Terms (9)

Animals Dose-Response Relationship, Drug Drug Discovery Humans Indoles Molecular Structure Rats Receptors, Muscarinic Structure-Activity Relationship

Connections (4)

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