The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.

Yang YP, Magnuson MA, Stein R, Wright CV
Development. 2017 144 (2): 248-257

PMID: 27993987 · PMCID: PMC5394757 · DOI:10.1242/dev.143123

MeSH Terms (15)

Animals Binding Sites Cell Differentiation Embryo, Mammalian Enhancer Elements, Genetic Gene Expression Regulation, Developmental Homeodomain Proteins Insulin-Secreting Cells Islets of Langerhans Mammals Mice Mice, Transgenic Organogenesis Species Specificity Trans-Activators

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