Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis.

Miyatsuka T, Kaneto H, Kajimoto Y, Hirota S, Arakawa Y, Fujitani Y, Umayahara Y, Watada H, Yamasaki Y, Magnuson MA, Miyazaki J, Hori M
Biochem Biophys Res Commun. 2003 310 (3): 1017-25

PMID: 14550306 · DOI:10.1016/j.bbrc.2003.09.108

MeSH Terms (28)

Animals Apoptosis Body Weight Cell Differentiation Cell Division Chickens Endocrine System Genetic Therapy Homeodomain Proteins Immunohistochemistry Insulin Integrases Liver Mice Mice, Transgenic Models, Genetic Pancreas Peptides Polymerase Chain Reaction Promoter Regions, Genetic Recombination, Genetic Reverse Transcriptase Polymerase Chain Reaction RNA Time Factors Tissue Distribution Trans-Activators Transgenes Viral Proteins

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