Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.

Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ
Mol Cell Proteomics. 2013 12 (2): 343-55

PMID: 23161513 · PMCID: PMC3567858 · DOI:10.1074/mcp.M112.022806

MeSH Terms (18)

Alleles Cell Line, Tumor Cell Proliferation Chromatography, Liquid Colonic Neoplasms Exosomes Humans Mutation Neoplasm Invasiveness Neoplasm Proteins Protein Transport Proteome Proto-Oncogene Proteins Proto-Oncogene Proteins p21(ras) ras Proteins Signal Transduction Tandem Mass Spectrometry Tumor Microenvironment

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