Glycine -methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates.

Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH
J Biol Chem. 2018 293 (30): 11944-11954

PMID: 29891549 · PMCID: PMC6066300 · DOI:10.1074/jbc.RA118.002568

MeSH Terms (16)

Animals Carbon Citric Acid Cycle Energy Metabolism Fatty Liver Gene Deletion Gluconeogenesis Glucose Glycine N-Methyltransferase Liver Male Metabolic Flux Analysis Methionine Mice Mice, Knockout S-Adenosylmethionine

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