From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.

Singh B, Coffey RJ
Semin Cell Dev Biol. 2014 28: 12-21

PMID: 24631356 · PMCID: PMC4105142 · DOI:10.1016/j.semcdb.2014.03.003

Since its discovery in 1978 and cloning in 1984, transforming growth factor-alpha (TGF-α, TGFA) has been one of the most extensively studied EGF receptor (EGFR) ligands. In this review, we provide a historical perspective on TGFA-related studies, highlighting what we consider important advances related to its function in normal and disease states.

Copyright © 2014 Elsevier Ltd. All rights reserved.

MeSH Terms (8)

Animals EGF Family of Proteins Epidermal Growth Factor Epithelial Cells Hair Humans Signal Transduction Transforming Growth Factor alpha

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