High spatial resolution imaging mass spectrometry and classical histology on a single tissue section.

Deutskens F, Yang J, Caprioli RM
J Mass Spectrom. 2011 46 (6): 568-71

PMID: 21630385 · PMCID: PMC3118566 · DOI:10.1002/jms.1926

The work presented in this report describes and demonstrates a protocol for protein imaging analysis of biological tissue using MALDI IMS where histological staining and MS analysis are performed on the same tissue section. Spatial image resolution is shown at 35 µm for sagittal sections of the cerebellum from rat brain.

Copyright © 2011 John Wiley & Sons, Ltd.

MeSH Terms (11)

Animals Cerebellum Female Histocytochemistry Histocytological Preparation Techniques Male Molecular Imaging Nerve Tissue Proteins Rats Rats, Sprague-Dawley Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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