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Growth factor modulation of melanoma growth stimulatory activity mRNA expression in human malignant melanoma cells correlates with cell growth.

Bordoni R, Thomas G, Richmond A
J Cell Biochem. 1989 39 (4): 421-8

PMID: 2722970 · DOI:10.1002/jcb.240390408

This report demonstrates that the expression of melanoma growth stimulatory activity (MGSA) mRNA can be modulated in a positive fashion in the Hs294T human melanoma cell line by PDGF and MGSA. There is close correlation between MGSA expression and the pattern of cell growth in Hs294T cells.

MeSH Terms (11)

Blotting, Northern Cell Division Chemokine CXCL1 Chemokines, CXC Growth Substances Humans Intercellular Signaling Peptides and Proteins Neoplasm Proteins Platelet-Derived Growth Factor RNA, Messenger Tumor Cells, Cultured

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