Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.

Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR
Nature. 2017 545 (7653): 243-247

PMID: 28467828 · PMCID: PMC5903850 · DOI:10.1038/nature22329

MeSH Terms (18)

Animals Anti-Glomerular Basement Membrane Disease Autoimmunity Base Sequence CD4-Positive T-Lymphocytes Collagen Type IV Cytokines Female Forkhead Transcription Factors HLA-DR1 Antigen HLA-DR Serological Subtypes Humans Immunodominant Epitopes Male Mice Mice, Transgenic Models, Molecular T-Lymphocytes, Regulatory

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