Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.

Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A
Oncotarget. 2016 7 (34): 54662-54675

PMID: 27323406 · PMCID: PMC5342371 · DOI:10.18632/oncotarget.9952

MeSH Terms (17)

Animals Catheter Ablation Cell Proliferation Cell Transformation, Neoplastic Hepatectomy Hepatocytes Humans Keratin-19 Liver Liver Neoplasms Mice Mice, Knockout Mice, Transgenic Retinoblastoma Protein Tissue Culture Techniques Transforming Growth Factor beta Tumor Suppressor Protein p53

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