Asymmetric expression of antivin/lefty1 in the early chick embryo.

Ishimaru Y, Yoshioka H, Tao H, Thisse B, Thisse C, V E Wright C, Hamada H, Ohuchi H, Noji S
Mech Dev. 2000 90 (1): 115-8

PMID: 10585569 · DOI:10.1016/s0925-4773(99)00232-4

Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo.

MeSH Terms (10)

Amino Acid Sequence Animals Cell Polarity Chick Embryo Embryo, Nonmammalian Gene Expression Regulation, Developmental Left-Right Determination Factors Molecular Sequence Data Sequence Alignment Transforming Growth Factor beta

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