About the DeBaun Lab

Our laboratory engages in clinical and translation research to address questions about the etiology, epidemiology, and optimal therapy for the management of children and adults with sickle cell disease and children with only asthma. We conduct patient oriented research locally, nationally and internationally.  The laboratory consists of a multi-disciplinary team (nurses, physiologist, pulmonologist, hematologists, neurologist, internist, pediatrician, basic scientists and patients/families affected by sickle cell disease and/or asthma.).


Featured publications

  1. Increased circulating fibrocytes are associated with higher reticulocyte percent in children with sickle cell anemia. Karafin MS, Dogra S, Rodeghier M, Burdick M, Mehrad B, Rose CE, Strieter RM, DeBaun MR, Strunk RC, Field JJ (2016) Pediatr Pulmonol 51(3): 295-9
    › Primary publication · 26130026 (PubMed) · PMC5559871 (PubMed Central)
  2. Haemophilia A carriers experience reduced health-related quality of life. Gilbert L, Paroskie A, Gailani D, Debaun MR, Sidonio RF (2015) Haemophilia 21(6): 761-5
    › Primary publication · 25930174 (PubMed) · PMC4619137 (PubMed Central)
  3. A cross-sectional study of bleeding phenotype in haemophilia A carriers. Paroskie A, Gailani D, DeBaun MR, Sidonio RF (2015) Br J Haematol 170(2): 223-8
    › Primary publication · 25832012 (PubMed) · PMC4490107 (PubMed Central)
  4. How I treat and manage strokes in sickle cell disease. Kassim AA, Galadanci NA, Pruthi S, DeBaun MR (2015) Blood 125(22): 3401-10
    › Primary publication · 25824688 (PubMed) · PMC4467906 (PubMed Central)
  5. Increased risk of severe vaso-occlusive episodes after initial acute chest syndrome in children with sickle cell anemia less than 4 years old: Sleep and asthma cohort. Vance LD, Rodeghier M, Cohen RT, Rosen CL, Kirkham FJ, Strunk RC, DeBaun MR (2015) Am J Hematol 90(5): 371-5
    › Primary publication · 25619382 (PubMed) · PMC4409481 (PubMed Central)
  6. The Association of Cytokine Levels With Cognitive Function in Children With Sickle Cell Disease and Normal MRI Studies of the Brain. Andreotti C, King AA, Macy E, Compas BE, DeBaun MR (2015) J Child Neurol 30(10): 1349-53
    › Primary publication · 25512362 (PubMed) · PMC4466214 (PubMed Central)
  7. Primary stroke prevention in Nigerian children with sickle cell disease (SPIN): challenges of conducting a feasibility trial. Galadanci NA, Abdullahi SU, Tabari MA, Abubakar S, Belonwu R, Salihu A, Neville K, Kirkham F, Inusa B, Shyr Y, Phillips S, Kassim AA, Jordan LC, Aliyu MH, Covert BV, DeBaun MR (2015) Pediatr Blood Cancer 62(3): 395-401
    › Primary publication · 25399822 (PubMed) · PMC4304992 (PubMed Central)
  8. Perspective: thinking beyond survival. DeBaun MR (2014) Nature 515(7526): S16
    › Primary publication · 25390138 (PubMed)
  9. Transfusions for silent cerebral infarcts in sickle cell anemia. DeBaun MR, Casella JF (2014) N Engl J Med 371(19): 1841-2
    › Primary publication · 25372094 (PubMed)
  10. Health-related quality of life in children with sickle cell anemia: impact of blood transfusion therapy. Beverung LM, Strouse JJ, Hulbert ML, Neville K, Liem RI, Inusa B, Fuh B, King A, Meier ER, Casella J, DeBaun MR, Panepinto JA, SIT trial investigators (2015) Am J Hematol 90(2): 139-43
    › Primary publication · 25345798 (PubMed) · PMC4304929 (PubMed Central)

Community Leaders

Contact Information

2200 Children's Way
Nashville, TN 37232
United States

Brittany Covert
6153228512 (p)

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Acute Disease Blastomeres Cause of Death Clinical Protocols Cyclin-Dependent Kinases Diastole Fungemia Infertility, Male Insulin-Like Growth Factor II Motivation Nitric Oxide Orientation Ovulation Induction Oxygen Patient-Centered Care Positive-Pressure Respiration Practice Guidelines as Topic Precursor Cell Lymphoblastic Leukemia-Lymphoma Renal Insufficiency ROC Curve