The primary area of research interest in the Beauchamp laboratory is in colorectal carcinogenesis, the biology of cancer cell invasion and metastasis, and in the identification of novel molecular biomarkers and therapeutic targets in colorectal and other alimentary tract malignancies. Our work applies DNA microarray and proteomic technology to identify novel biomarkers and therapeutic targets in human colorectal cancer samples. We also use molecular genetics and cell biological approaches to examine mechanistic questions in cancer biology in both cell culture and mouse models.
1161 21st Ave. South
D2300 Medical Center North
Nashville, TN 37212-2730
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MeSH terms are retrieved from PubMed records. Learn more.
Key: MeSH Term KeywordAnoikis Carcinoma Cell Line, Tumor Cell Membrane Ceramides colon cancer Gamma Rays gene expression profiling HCT116 Cells Intestine, Small Lasers Liver Neoplasms metastasis Microarray Analysis Microdissection Mitogen-Activated Protein Kinase Kinases mouse models of cancer Nerve Tissue Proteins Plasminogen Activator Inhibitor 1 RNA Stability smad signaling TGF signaling Transcription, Genetic Tumor Suppressor Proteins Unnecessary Procedures wnt signaling Xenopus