Vanderbilt Center for Stem Cell Biology

The Vanderbilt Center for Stem Cell Biology facilitates studies of the basic biology of stem and progenitor cells through partnerships with the Program in Developmental Biology (PDB) and the Department of Cell and Developmental Biology.  It is home to two shared resources, the Vanderbilt Genome Editing Resource (VGER) and Creative Data Solutions (CDS), and oversees the Stem and Progenitor Cell Interest Group (SPRING) meetings.

Featured Collections

• Information

Publications

Featured publications

1. Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis. Katholnig K, Schütz B, Fritsch SD, Schörghofer D, Linke M, Sukhbaatar N, Matschinger JM, Unterleuthner D, Hirtl M, Lang M, Herac M, Spittler A, Bergthaler A, Schabbauer G, Bergmann M, Dolznig H, Hengstschläger M, Magnuson MA, Mikula M, Weichhart T (2019) JCI Insight 4(20)
   › Primary publication · 31619583 (PubMed)
2. Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism. Krah NM, Narayanan SM, Yugawa DE, Straley JA, Wright CVE, MacDonald RJ, Murtaugh LC (2019) Dev Cell 50(6): 744-754.e4
   › Primary publication · 31422917 (PubMed) · PMC6776997 (PubMed Central)
3. Differential Cell Susceptibilities to Kras in the Setting of Obstructive Chronic Pancreatitis. Shi C, Pan FC, Kim JN, Washington MK, Padmanabhan C, Meyer CT, Kopp JL, Sander M, Gannon M, Beauchamp RD, Wright CV, Means AL (2019) Cell Mol Gastroenterol Hepatol
   › Primary publication · 31310834 (PubMed)
4. Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells. Trogden KP, Zhu X, Lee JS, Wright CVE, Gu G, Kaverina I (2019) Curr Biol 29(14): 2339-2350.e5
   › Primary publication · 31303487 (PubMed) · PMC6698911 (PubMed Central)
5. Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis. Wen HJ, Gao S, Wang Y, Ray M, Magnuson MA, Wright CVE, Di Magliano MP, Frankel TL, Crawford HC (2019) Cell Mol Gastroenterol Hepatol 8(2): 173-192
   › Primary publication · 31125624 (PubMed) · PMC6661420 (PubMed Central)
6. Imaging mass spectrometry enables molecular profiling of mouse and human pancreatic tissue. Prentice BM, Hart NJ, Phillips N, Haliyur R, Judd A, Armandala R, Spraggins JM, Lowe CL, Boyd KL, Stein RW, Wright CV, Norris JL, Powers AC, Brissova M, Caprioli RM (2019) Diabetologia 62(6): 1036-1047
   › Primary publication · 30955045 (PubMed) · PMC6553460 (PubMed Central)
7. Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences. Stancill JS, Osipovich AB, Cartailler JP, Magnuson MA (2019) Am J Physiol Endocrinol Metab 316(2): E196-E209
   › Primary publication · 30532991 (PubMed) · PMC6397359 (PubMed Central)
8. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon α-cells. Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Oropeza D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright CEV, Thomas MK, Furuyama K, Chera S, Herrera PL (2018) Nat Cell Biol 20(11): 1267-1277
   › Primary publication · 30361701 (PubMed) · PMC6215453 (PubMed Central)
9. The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis. Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H (2018) J Clin Invest 128(8): 3475-3489
   › Primary publication · 30010625 (PubMed) · PMC6063489 (PubMed Central)
10. Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M (2018) Cell Rep 24(1): 79-94
    › Primary publication · 29972793 (PubMed)

Community Leaders

• Mark Magnuson
  Director
• Jean-Philippe Cartailler
  Director - VCSCB Informatics
• Pam Uttz
  Administrative Assistant III

Contact Information

9465 MRB-IV
2213 Garland Avenue
Nashville, TN 37232
United States

Pam Uttz
615-322-7006 (p)
615-322-6645 (f)
Email

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