The Vanderbilt Center for Stem Cell Biology facilitates studies of the basic biology of stem and progenitor cells through partnerships with the Program in Developmental Biology (PDB) and the Department of Cell and Developmental Biology.  It is home to two shared resources, the Vanderbilt Genome Editing Resource (VGER) and Creative Data Solutions (CDS), and oversees the Stem and Progenitor Cell Interest Group (SPRING) meetings.

 

Featured Collections

Publications

Featured publications

  1. Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences. Stancill JS, Osipovich AB, Cartailler JP, Magnuson MA (2019) Am J Physiol Endocrinol Metab 316(2): E196-E209
    › Primary publication · 30532991 (PubMed) · PMC6397359 (PubMed Central)
  2. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon α-cells. Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Oropeza D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright CEV, Thomas MK, Furuyama K, Chera S, Herrera PL (2018) Nat Cell Biol 20(11): 1267-1277
    › Primary publication · 30361701 (PubMed) · PMC6215453 (PubMed Central)
  3. The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis. Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H (2018) J Clin Invest 128(8): 3475-3489
    › Primary publication · 30010625 (PubMed) · PMC6063489 (PubMed Central)
  4. Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M (2018) Cell Rep 24(1): 79-94
    › Primary publication · 29972793 (PubMed)
  5. Genome Editing and Induced Pluripotent Stem Cell Technologies for Personalized Study of Cardiovascular Diseases. Chun YW, Durbin MD, Hong CC (2018) Curr Cardiol Rep 20(6): 38
    › Primary publication · 29666931 (PubMed) · PMC6204334 (PubMed Central)
  6. Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles. Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G (2018) Dev Cell 45(3): 347-361.e5
    › Primary publication · 29656931 (PubMed) · PMC5962294 (PubMed Central)
  7. Cytosolic phosphoenolpyruvate carboxykinase as a cataplerotic pathway in the small intestine. Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JA, Fu X, Browning JD, Magnuson MA, Burgess SC (2018) Am J Physiol Gastrointest Liver Physiol 315(2): G249-G258
    › Primary publication · 29631378 (PubMed) · PMC6139646 (PubMed Central)
  8. Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. Ray TA, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert SW, Wright CV, Field GD, Kay JN (2018) Elife
    › Primary publication · 29611808 (PubMed) · PMC5931800 (PubMed Central)
  9. ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice. Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H (2018) Gastroenterology 155(1): 194-209.e2
    › Primary publication · 29604291 (PubMed)
  10. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H (2018) Mol Metab : 57-68
    › Primary publication · 29396371 (PubMed) · PMC5870105 (PubMed Central)