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The Vanderbilt Center for Stem Cell Biology facilitates studies of the basic biology of stem and progenitor cells through partnerships with the Program in Developmental Biology (PDB) and the Department of Cell and Developmental Biology.  It is home to two shared resources, the Transgenic Mouse/ESC Shared Resource (TMESCSR) and Creative Data Solutions (CDS), and oversees the Stem and Progenitor Cell Interest Group (SPRING) meetings.

 

Featured Collections

Publications

Featured publications

  1. ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice. Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H (2018) Gastroenterology
    › Primary publication · 29604291 (PubMed)
  2. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H (2018) Mol Metab : 57-68
    › Primary publication · 29396371 (PubMed)
  3. Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes. Osipovich AB, Magnuson MA (2018) Cell Stem Cell 22(1): 12-13
    › Primary publication · 29304337 (PubMed)
  4. Motivation for Launching a Cancer Metastasis Inhibition (CMI) Program. Pulley JM, Jerome RN, Ogletree ML, Bernard GR, Lavieri RR, Zaleski NM, Hong CC, Shirey-Rice JK, Arteaga CL, Mayer IA, Holroyd KJ, Cook RS (2018) Target Oncol 13(1): 61-68
    › Primary publication · 29218624 (PubMed) · PMC5826865 (PubMed Central)
  5. EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity. Löf-Öhlin ZM, Nyeng P, Bechard ME, Hess K, Bankaitis E, Greiner TU, Ameri J, Wright CV, Semb H (2017) Nat Cell Biol 19(11): 1313-1325
    › Primary publication · 29058721 (PubMed)
  6. Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis. Larsen HL, Martín-Coll L, Nielsen AV, Wright CVE, Trusina A, Kim YH, Grapin-Botton A (2017) Nat Commun 8(1): 605
    › Primary publication · 28928395 (PubMed) · PMC5605525 (PubMed Central)
  7. Production of Single Contracting Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Matrigel Mattress Technique. Cadar AG, Feaster TK, Durbin MD, Hong CC (2017) Curr Protoc Stem Cell Biol : 4A.14.1-4A.14.7
    › Primary publication · 28806851 (PubMed) · PMC5577013 (PubMed Central)
  8. FUCCI tracking shows cell-cycle-dependent Neurog3 variation in pancreatic progenitors. Bechard ME, Bankaitis ED, Ustione A, Piston DW, Magnuson MA, Wright CVE (2017) Genesis 55(9)
    › Primary publication · 28772022 (PubMed) · PMC5750046 (PubMed Central)
  9. Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning. Spaeth JM, Gupte M, Perelis M, Yang YP, Cyphert H, Guo S, Liu JH, Guo M, Bass J, Magnuson MA, Wright C, Stein R (2017) Diabetes 66(11): 2830-2839
    › Primary publication · 28705881 (PubMed) · PMC5652607 (PubMed Central)
  10. Hypoplastic Left Heart Syndrome Sequencing Reveals a Novel NOTCH1 Mutation in a Family with Single Ventricle Defects. Durbin MD, Cadar AG, Williams CH, Guo Y, Bichell DP, Su YR, Hong CC (2017) Pediatr Cardiol 38(6): 1232-1240
    › Primary publication · 28608148 (PubMed) · PMC5577922 (PubMed Central)

Community Leaders

Contact Information

9465 MRB-IV
2213 Garland Avenue
Nashville, TN 37232
United States

Pam Uttz
615-322-7006 (p)
615-322-6645 (f)
Email

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Adenocarcinoma, Clear Cell Adenoviridae Aged cell reprogramming Cellular Reprogramming Codon, Nonsense developmental biology differentiation Gene Deletion Gene Expression Profiling Heart Ventricles Keratinocytes Mice, Knockout Microvessels Mitochondria Oxidative Phosphorylation Protein Kinase C Radiation Tolerance S100 Calcium-Binding Protein A4 S100 Calcium Binding Protein A6 stem cell Tetradecanoylphorbol Acetate Tumor Cells, Cultured X-Rays