The Vanderbilt Center for Stem Cell Biology facilitates studies of the basic biology of stem and progenitor cells through partnerships with the Program in Developmental Biology (PDB) and the Department of Cell and Developmental Biology.  It is home to two shared resources, the Transgenic Mouse/ESC Shared Resource (TMESCSR) and Creative Data Solutions (CDS), and oversees the Stem and Progenitor Cell Interest Group (SPRING) meetings.

 

Featured Collections

Publications

Featured publications

  1. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon α-cells. Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Oropeza D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright CEV, Thomas MK, Furuyama K, Chera S, Herrera PL (2018) Nat Cell Biol 20(11): 1267-1277
    › Primary publication · 30361701 (PubMed) · PMC6215453 (PubMed Central)
  2. The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis. Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H (2018) J Clin Invest 128(8): 3475-3489
    › Primary publication · 30010625 (PubMed)
  3. Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M (2018) Cell Rep 24(1): 79-94
    › Primary publication · 29972793 (PubMed)
  4. Genome Editing and Induced Pluripotent Stem Cell Technologies for Personalized Study of Cardiovascular Diseases. Chun YW, Durbin MD, Hong CC (2018) Curr Cardiol Rep 20(6): 38
    › Primary publication · 29666931 (PubMed)
  5. Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles. Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G (2018) Dev Cell
    › Primary publication · 29656931 (PubMed)
  6. Cytosolic Phosphoenolpyruvate Carboxykinase as a Cataplerotic Pathway in the Small Intestine. Potts A, Uchida A, Deja S, Berglund ED, Kucejova B, Duarte JAG, Fu X, Browning JD, Magnuson MA, Burgess SC (2018) Am J Physiol Gastrointest Liver Physiol
    › Primary publication · 29631378 (PubMed)
  7. Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. Ray TA, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert SW, Wright CVE, Field GD, Kay JN (2018) Elife
    › Primary publication · 29611808 (PubMed)
  8. ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice. Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H (2018) Gastroenterology
    › Primary publication · 29604291 (PubMed)
  9. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, Staiger H, Häring HU, Lederer G, Meitinger T, Cernilogar FM, Schotta G, Irmler M, Beckers J, Hrabě de Angelis M, Ray M, Wright CVE, Bakhti M, Lickert H (2018) Mol Metab : 57-68
    › Primary publication · 29396371 (PubMed)
  10. Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes. Osipovich AB, Magnuson MA (2018) Cell Stem Cell 22(1): 12-13
    › Primary publication · 29304337 (PubMed)

Community Leaders

Contact Information

9465 MRB-IV
2213 Garland Avenue
Nashville, TN 37232
United States

Pam Uttz
615-322-7006 (p)
615-322-6645 (f)
Email

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Adenocarcinoma, Clear Cell Adenoviridae Aged cell reprogramming Cellular Reprogramming Codon, Nonsense developmental biology differentiation Gene Deletion Gene Expression Profiling Keratinocytes Mice, Knockout Microvessels Mitochondria Oxidative Phosphorylation Protein Kinase C Radiation Tolerance Receptor, Transforming Growth Factor-beta Type II S100 Calcium-Binding Protein A4 S100 Calcium Binding Protein A6 stem cell Tetradecanoylphorbol Acetate Tumor Cells, Cultured X-Rays