The Vanderbilt University Cancer & Immunology Core (CIC) provides fee-for-service mass cytometry and other advanced cytometry services using well-established CIC Panels of metal-conjugated antibodies and standardized protocols. We also have a website at:


Featured publications

  1. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. Barone SM, Paul AG, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM (2021) Elife
    › Primary publication · 34350827 (PubMed) · PMC8370768 (PubMed Central)
  2. Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine. Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker L, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, Carnahan RH, Rathmell JC, Bonami RH, Georgiev IS, Irish JM (2021) bioRxiv
    › Primary publication · 34341788 (PubMed) · PMC8328055 (PubMed Central)
  3. Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation. Ramsey HE, Stengel K, Pino JC, Johnston G, Childress M, Gorska AE, Arrate PM, Fuller L, Villaume M, Fischer MA, Ferrell PB, Roe CE, Zou J, Lubbock ALR, Stubbs M, Zinkel S, Irish JM, Lopez CF, Hiebert S, Savona MR (2021) Target Oncol 16(5): 663-674
    › Primary publication · 34324169 (PubMed) · PMC8667588 (PubMed Central)
  4. HLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behavior. Senosain MF, Zou Y, Novitskaya T, Vasiukov G, Balar AB, Rowe DJ, Doxie DB, Lehman JM, Eisenberg R, Maldonado F, Zijlstra A, Novitskiy SV, Irish JM, Massion PP (2021) Sci Rep 11(1): 14424
    › Primary publication · 34257356 (PubMed) · PMC8277797 (PubMed Central)
  5. CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant. Yeh AC, Varelias A, Reddy A, Barone SM, Olver SD, Chilson K, Onstad LE, Ensbey KS, Henden AS, Samson L, Jaeger CA, Bi T, Dahlman KB, Kim TK, Zhang P, Degli-Esposti MA, Newell EW, Jagasia MH, Irish JM, Lee SJ, Hill GR (2021) Blood 138(26): 2874-2885
    › Primary publication · 34115118 (PubMed) · PMC8718626 (PubMed Central)
  6. DebarcodeR increases fluorescent cell barcoding capacity and accuracy. Reisman BJ, Barone SM, Bachmann BO, Irish JM (2021) Cytometry A 99(9): 946-953
    › Primary publication · 33960644 (PubMed) · PMC8410645 (PubMed Central)
  7. Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8 T cells during the primary immune response. Levine LS, Hiam-Galvez KJ, Marquez DM, Tenvooren I, Madden MZ, Contreras DC, Dahunsi DO, Irish JM, Oluwole OO, Rathmell JC, Spitzer MH (2021) Immunity 54(4): 829-844.e5
    › Primary publication · 33705706 (PubMed) · PMC8046726 (PubMed Central)
  8. A Cytometrist's Guide to Coordinating and Performing Effective COVID-19 Research. Chattopadhyay PK, Filby A, Jellison ER, Ferrari G, Green C, Cherian S, Irish J, Litwin V, other members of the ISAC COVID-19 Work Group (2021) Cytometry A 99(1): 11-18
    › Primary publication · 32881296 (PubMed) · PMC7461086 (PubMed Central)
  9. CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation. Beckermann KE, Hongo R, Ye X, Young K, Carbonell K, Healey DCC, Siska PJ, Barone S, Roe CE, Smith CC, Vincent BG, Mason FM, Irish JM, Rathmell WK, Rathmell JC (2020) JCI Insight 5(16)
    › Primary publication · 32814710 (PubMed) · PMC7455120 (PubMed Central)
  10. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. Barone SM, Paul AGA, Muehling LM, Lannigan JA, Kwok WW, Turner RB, Woodfolk JA, Irish JM (2020) bioRxiv
    › Primary publication · 32766581 (PubMed) · PMC7402038 (PubMed Central)

Community Leaders

Contact Information

2220 Pierce Ave
734 Preston Research Building (PRB)
Nashville, TN 37232
United States
(615) 936-3460 (p)

Caroline Roe
(615) 936-3460 (p)

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Animals Antibodies, Neoplasm Bone Marrow Case-Control Studies CD4 Antigens CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes CD40 Antigens Chronic Disease Cryopreservation Cytomegalovirus Infections Kidney Neoplasms Monocytes Neoplasms Prospective Studies Stem Cells Streptomyces Unsupervised Machine Learning Vaccination Young Adult