The Vanderbilt University Cancer & Immunology Core (CIC) provides fee-for-service mass cytometry and other advanced cytometry services using well-established CIC Panels of metal-conjugated antibodies and standardized protocols. We also have a website at: https://my.vanderbilt.edu/cancerimmunology/.

Publications

Featured publications

  1. High-Dimensional Data Analysis Algorithms Yield Comparable Results for Mass Cytometry and Spectral Flow Cytometry Data. Ferrer-Font L, Mayer JU, Old S, Hermans IF, Irish J, Price KM (2020) Cytometry A
    › Primary publication · 32293794 (PubMed)
  2. Training Novices in Generation and Analysis of High-Dimensional Human Cell Phospho-Flow Cytometry Data. Roe CE, Hayes MJ, Barone SM, Irish JM (2020) Curr Protoc Cytom 93(1): e71
    › Primary publication · 32250555 (PubMed)
  3. Mass cytometry defines distinct immune profile in germinal center B-cell lymphomas. Roussel M, Lhomme F, Roe CE, Bartkowiak T, Gravelle P, Laurent C, Fest T, Irish JM (2020) Cancer Immunol Immunother 69(3): 407-420
    › Primary publication · 31919622 (PubMed)
  4. Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry. Roussel M, Bartkowiak T, Irish JM (2019) Methods Mol Biol : 217-226
    › Primary publication · 31077108 (PubMed) · PMC6886519 (PubMed Central)
  5. Human Germinal Center B Cells Differ from Naïve and Memory B Cells in CD40 Expression and CD40L-Induced Signaling Response. Huse K, Wogsland CE, Polikowsky HG, Diggins KE, Smeland EB, Myklebust JH, Irish JM (2019) Cytometry A 95(4): 442-449
    › Primary publication · 30838773 (PubMed) · PMC6711772 (PubMed Central)
  6. Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types. Greenplate AR, McClanahan DD, Oberholtzer BK, Doxie DB, Roe CE, Diggins KE, Leelatian N, Rasmussen ML, Kelley MC, Gama V, Siska PJ, Rathmell JC, Ferrell PB, Johnson DB, Irish JM (2019) Cancer Immunol Res 7(1): 86-99
    › Primary publication · 30413431 (PubMed) · PMC6318034 (PubMed Central)
  7. Machine learning reveals chronic graft--host disease phenotypes and stratifies survival after stem cell transplant for hematologic malignancies. Gandelman JS, Byrne MT, Mistry AM, Polikowsky HG, Diggins KE, Chen H, Lee SJ, Arora M, Cutler C, Flowers M, Pidala J, Irish JM, Jagasia MH (2019) Haematologica 104(1): 189-196
    › Primary publication · 30237265 (PubMed) · PMC6312024 (PubMed Central)
  8. Genomic Profiling of T-Cell Neoplasms Reveals Frequent and Mutations With Clonal Evasion From Targeted Therapies. Greenplate A, Wang K, Tripathi RM, Palma N, Ali SM, Stephens PJ, Miller VA, Shyr Y, Guo Y, Reddy NM, Kozhaya L, Unutmaz D, Chen X, Irish JM, Davé UP (2018) JCO Precis Oncol
    › Primary publication · 30079384 (PubMed) · PMC6072266 (PubMed Central)
  9. Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics. Earl DC, Ferrell PB, Leelatian N, Froese JT, Reisman BJ, Irish JM, Bachmann BO (2018) Nat Commun 9(1): 39
    › Primary publication · 29295987 (PubMed) · PMC5750220 (PubMed Central)
  10. Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma. Siska PJ, Beckermann KE, Mason FM, Andrejeva G, Greenplate AR, Sendor AB, Chiang YJ, Corona AL, Gemta LF, Vincent BG, Wang RC, Kim B, Hong J, Chen CL, Bullock TN, Irish JM, Rathmell WK, Rathmell JC (2017) JCI Insight 2(12)
    › Primary publication · 28614802 (PubMed) · PMC5470888 (PubMed Central)

Community Leaders

Contact Information

2220 Pierce Ave
734 Preston Research Building (PRB)
Nashville, TN 37232
United States
(615) 936-3460 (p)

Caroline Roe
(615) 936-3460 (p)
Email

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Adult Algorithms Bone Marrow Brain Neoplasms CD40 Antigens Chromatography, Liquid Chronic Disease Cryopreservation Germinal Center Image Cytometry Jurkat Cells Melanoma Middle Aged Monocytes Multivariate Analysis Neoplasms Prospective Studies Pyridones Streptomyces Young Adult