The Vanderbilt University Cancer & Immunology Core (CIC) provides fee-for-service mass cytometry and other advanced cytometry services using well-established CIC Panels of metal-conjugated antibodies and standardized protocols. We also have a website at: https://my.vanderbilt.edu/cancerimmunology/.

Publications

Featured publications

  1. Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma. Siska PJ, Beckermann KE, Mason FM, Andrejeva G, Greenplate AR, Sendor AB, Chiang YJ, Corona AL, Gemta LF, Vincent BG, Wang RC, Kim B, Hong J, Chen CL, Bullock TN, Irish JM, Rathmell WK, Rathmell JC (2017) JCI Insight 2(12)
    › Primary publication · 28614802 (PubMed)
  2. Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow. Roussel M, Ferrell PB, Greenplate AR, Lhomme F, Le Gallou S, Diggins KE, Johnson DB, Irish JM (2017) J Leukoc Biol
    › Primary publication · 28400539 (PubMed)
  3. Preparing Viable Single Cells from Human Tissue and Tumors for Cytomic Analysis. Leelatian N, Doxie DB, Greenplate AR, Sinnaeve J, Ihrie RA, Irish JM (2017) Curr Protoc Mol Biol : 25C.1.1-25C.1.23
    › Primary publication · 28369679 (PubMed)
  4. Characterizing cell subsets using marker enrichment modeling. E Diggins K, R Greenplate A, Leelatian N, E Wogsland C, M Irish J (2017) Nat Methods
    › Primary publication · 28135256 (PubMed)
  5. Mass cytometry of follicular lymphoma tumors reveals intrinsic heterogeneity in proteins including HLA-DR and a deficit in non-malignant plasmablast and germinal center B cell populations. Wogsland CE, Greenplate AR, Kolstad A, Myklebust JH, Irish JM, Huse K (2016) Cytometry B Clin Cytom
    › Primary publication · 27933753 (PubMed)
  6. Single cell analysis of human tissues and solid tumors with mass cytometry. Leelatian N, Doxie DB, Greenplate AR, Mobley BC, Lehman JM, Sinnaeve J, Kauffmann RM, Werkhaven JA, Mistry AM, Weaver KD, Thompson RC, Massion PP, Hooks MA, Kelley MC, Chambless LB, Ihrie RA, Irish JM (2016) Cytometry B Clin Cytom
    › Primary publication · 27598832 (PubMed)
  7. Systems immune monitoring in cancer therapy. Greenplate AR, Johnson DB, Ferrell PB, Irish JM (2016) Eur J Cancer : 77-84
    › Primary publication · 27155446 (PubMed) · PMC4885747 (PubMed Central)
  8. High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy. Ferrell PB, Diggins KE, Polikowsky HG, Mohan SR, Seegmiller AC, Irish JM (2016) PLoS One 11(4): e0153207
    › Primary publication · 27074138 (PubMed) · PMC4830605 (PubMed Central)
  9. Myelodysplastic Syndrome Revealed by Systems Immunology in a Melanoma Patient Undergoing Anti-PD-1 Therapy. Greenplate AR, Johnson DB, Roussel M, Savona MR, Sosman JA, Puzanov I, Ferrell PB, Irish JM (2016) Cancer Immunol Res 4(6): 474-80
    › Primary publication · 26966176 (PubMed) · PMC4891280 (PubMed Central)
  10. Multiparameter analysis of stimulated human peripheral blood mononuclear cells: A comparison of mass and fluorescence cytometry. Nicholas KJ, Greenplate AR, Flaherty DK, Matlock BK, Juan JS, Smith RM, Irish JM, Kalams SA (2016) Cytometry A 89(3): 271-80
    › Primary publication · 26599989 (PubMed) · PMC4808335 (PubMed Central)

Community Leaders

Contact Information

2220 Pierce Ave
734 Preston Research Building (PRB)
Nashville, TN 37232
United States
(615) 936-3460 (p)

Caroline Roe
(615) 936-3460 (p)
Email

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Aged Antigens, CD Bone Marrow Female Flow Cytometry Humans Immunophenotyping Induction Chemotherapy Lanthanoid Series Elements Leukemia, Myeloid, Acute Leukocytes, Mononuclear Lymphocyte Activation Male Mass Spectrometry Middle Aged Multivariate Analysis Phenotype Pilot Projects Treatment Outcome Young Adult