Vanderbilt is at the center of an epidemic of cancers caused by human papillomavirus (HPV) infection. These HPV-associated cancers are potentially preventable and include cancers of the head and neck, lower reproductive tract (cervix, vagina, vulva, penis), and anus. Vanderbilt is well poised to address critical gaps in prevention and early detection strategies that could significantly reduce the number of individuals who are diagnosed with or succumb to these cancers. We will develop supportive infrastructure and educational programs that engage an interdisciplinary team of investigators from the Schools of Medicine, Nursing, Biomedical Engineering, and Education as well as Vanderbilt students to lay the groundwork for a consortium focused on HPV-associated cancers. Faculty and students will conduct pilot projects designed to: 1) characterize the burden of HPV-associated cancers seen at Vanderbilt; 2) improve HPV vaccination rates in Tennessee; and 3) develop innovative early detection strategies for HPV-associated head and neck cancer.



Featured publications

  1. Proteomics show antigen presentation processes in human immune cells after AS03-H5N1 vaccination. Galassie AC, Goll JB, Samir P, Jensen TL, Hoek KL, Howard LM, Allos TM, Niu X, Gordy LE, Creech CB, Hill H, Joyce S, Edwards KM, Link AJ (2017) Proteomics 17(12)
    › Primary publication · 28508465 (PubMed) · PMC5736144 (PubMed Central)
  2. HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection. Beachler DC, Waterboer T, Pierce Campbell ChM, Ingles DJ, Kuhs KA, Nyitray AG, Hildesheim A, Pawlita M, Kreimer AR, Giuliano AR (2016) Papillomavirus Res : 141-144
    › Primary publication · 28239675 (PubMed) · PMC5322843 (PubMed Central)
  3. HPV vaccine use among African American girls: qualitative formative research using a participatory social marketing approach. Hull PC, Williams EA, Khabele D, Dean C, Bond B, Sanderson M (2014) Gynecol Oncol : S13-20
    › Primary publication · 24491412 (PubMed) · PMC3966189 (PubMed Central)

Funding generously provided by the Vanderbilt Trans-Institutional Programs (TIPs).

Community Leaders

Contact Information

1161 21st Ave S
R-1200 Medical Center North
Nashville, TN 37232

No contact person provided

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Adjuvants, Immunologic African Americans Antigen Presentation B-Lymphocytes cancer Child Cross-Sectional Studies Epi-Center Epidemiology Focus Groups Gynecology Health Promotion HPV HPV-Associated Human Papillomavirus Infections Influenza A Virus, H5N1 Subtype Monocytes Oncology Otolaryngology Papillomavirus Infections Papillomavirus Vaccines Parents Patient Education as Topic Protein Interaction Maps Proteome Proteomics Qualitative Research Social Marketing T-Lymphocytes TIPs