Marcela Brissova, PhD

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Publications

The following timeline graph is generated from all co-authored publications.

1. α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC (2018) Cell Rep 22(10): 2667-2676
   › Primary publication · 29514095 (PubMed) · PMC6368357 (PubMed Central)
2. Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity. Weitz JR, Makhmutova M, Almaça J, Stertmann J, Aamodt K, Brissova M, Speier S, Rodriguez-Diaz R, Caicedo A (2018) Diabetologia 61(1): 182-192
   › Primary publication · 28884198 (PubMed) · PMC5868749 (PubMed Central)
3. Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors. Cogger KF, Sinha A, Sarangi F, McGaugh EC, Saunders D, Dorrell C, Mejia-Guerrero S, Aghazadeh Y, Rourke JL, Screaton RA, Grompe M, Streeter PR, Powers AC, Brissova M, Kislinger T, Nostro MC (2017) Nat Commun 8(1): 331
   › Primary publication · 28835709 (PubMed) · PMC5569081 (PubMed Central)
4. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC (2017) Nat Med 23(8): 1004
   › Primary publication · 28777787 (PubMed) · PMC5724517 (PubMed Central)
5. Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC (2017) Nat Med 23(2): 264
   › Primary publication · 28170374 (PubMed)
6. Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes. Babon JA, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC (2016) Nat Med 22(12): 1482-1487
   › Primary publication · 27798614 (PubMed) · PMC5140746 (PubMed Central)
7. Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration. Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC (2016) Am J Physiol Endocrinol Metab 311(5): E859-E868
   › Primary publication · 27624103 (PubMed) · PMC5130356 (PubMed Central)
8. Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells. Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV (2015) Development 142(21): 3637-48
   › Primary publication · 26534984 (PubMed) · PMC4647212 (PubMed Central)
9. Microtubules Negatively Regulate Insulin Secretion in Pancreatic β Cells. Zhu X, Hu R, Brissova M, Stein RW, Powers AC, Gu G, Kaverina I (2015) Dev Cell 34(6): 656-68
   › Primary publication · 26418295 (PubMed) · PMC4594944 (PubMed Central)
10. Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes. Brissova M, Shostak A, Fligner CL, Revetta FL, Washington MK, Powers AC, Hull RL (2015) J Histochem Cytochem 63(8): 637-45
    › Primary publication · 26216139 (PubMed) · PMC4530394 (PubMed Central)
11. Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function. Burke SJ, May AL, Noland RC, Lu D, Brissova M, Powers AC, Sherrill EM, Karlstad MD, Campagna SR, Stephens JM, Collier JJ (2015) J Biol Chem 290(21): 13401-16
    › Primary publication · 25851902 (PubMed) · PMC4505588 (PubMed Central)
12. Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles. Kayton NS, Poffenberger G, Henske J, Dai C, Thompson C, Aramandla R, Shostak A, Nicholson W, Brissova M, Bush WS, Powers AC (2015) Am J Physiol Endocrinol Metab 308(7): E592-602
    › Primary publication · 25648831 (PubMed) · PMC4385877 (PubMed Central)
13. Automated quantification of pancreatic β-cell mass. Golson ML, Bush WS, Brissova M (2014) Am J Physiol Endocrinol Metab 306(12): E1460-7
    › Primary publication · 24760991 (PubMed) · PMC4059986 (PubMed Central)
14. Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC (2014) Development 141(7): 1480-91
    › Primary publication · 24574008 (PubMed) · PMC3957372 (PubMed Central)
15. Pancreas development in humans. Pan FC, Brissova M (2014) Curr Opin Endocrinol Diabetes Obes 21(2): 77-82
    › Primary publication · 24569548 (PubMed) · PMC4753768 (PubMed Central)
16. Islet microenvironment, modulated by vascular endothelial growth factor-A signaling, promotes β cell regeneration. Brissova M, Aamodt K, Brahmachary P, Prasad N, Hong JY, Dai C, Mellati M, Shostak A, Poffenberger G, Aramandla R, Levy SE, Powers AC (2014) Cell Metab 19(3): 498-511
    › Primary publication · 24561261 (PubMed) · PMC4012856 (PubMed Central)
17. Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets. Reinert RB, Brissova M, Shostak A, Pan FC, Poffenberger G, Cai Q, Hundemer GL, Kantz J, Thompson CS, Dai C, McGuinness OP, Powers AC (2013) Diabetes 62(12): 4154-64
    › Primary publication · 23884891 (PubMed) · PMC3837071 (PubMed Central)
18. Pancreatic islet vasculature adapts to insulin resistance through dilation and not angiogenesis. Dai C, Brissova M, Reinert RB, Nyman L, Liu EH, Thompson C, Shostak A, Shiota M, Takahashi T, Powers AC (2013) Diabetes 62(12): 4144-53
    › Primary publication · 23630302 (PubMed) · PMC3837044 (PubMed Central)
19. VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue. Christoffersson G, Vågesjö E, Vandooren J, Lidén M, Massena S, Reinert RB, Brissova M, Powers AC, Opdenakker G, Phillipson M (2012) Blood 120(23): 4653-62
    › Primary publication · 22966168 (PubMed) · PMC3512240 (PubMed Central)
20. Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation. Cai Q, Brissova M, Reinert RB, Pan FC, Brahmachary P, Jeansson M, Shostak A, Radhika A, Poffenberger G, Quaggin SE, Jerome WG, Dumont DJ, Powers AC (2012) Dev Biol 367(1): 40-54
    › Primary publication · 22546694 (PubMed) · PMC3391601 (PubMed Central)
21. Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice. Reinert RB, Kantz J, Misfeldt AA, Poffenberger G, Gannon M, Brissova M, Powers AC (2012) PLoS One 7(3): e33529
    › Primary publication · 22470452 (PubMed) · PMC3314663 (PubMed Central)
22. Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets. Dai C, Brissova M, Hang Y, Thompson C, Poffenberger G, Shostak A, Chen Z, Stein R, Powers AC (2012) Diabetologia 55(3): 707-18
    › Primary publication · 22167125 (PubMed) · PMC3268985 (PubMed Central)
23. Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG, Gannon M, Powers AC, Dempsey PJ (2010) Diabetes 59(12): 3090-8
    › Primary publication · 20802254 (PubMed) · PMC2992770 (PubMed Central)
24. Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation. Virostko J, Radhika A, Poffenberger G, Chen Z, Brissova M, Gilchrist J, Coleman B, Gannon M, Jansen ED, Powers AC (2010) Mol Imaging Biol 12(1): 42-53
    › Primary publication · 19548035 (PubMed) · PMC3822006 (PubMed Central)
25. Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets. Nyman LR, Wells KS, Head WS, McCaughey M, Ford E, Brissova M, Piston DW, Powers AC (2008) J Clin Invest 118(11): 3790-7
    › Primary publication · 18846254 (PubMed) · PMC2564611 (PubMed Central)
26. Revascularization of transplanted islets: can it be improved? Brissova M, Powers AC (2008) Diabetes 57(9): 2269-71
    › Primary publication · 18753672 (PubMed) · PMC2518476 (PubMed Central)
27. Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC (2006) Diabetes 55(11): 2974-85
    › Primary publication · 17065333 (PubMed)
28. Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation. Blomeier H, Zhang X, Rives C, Brissova M, Hughes E, Baker M, Powers AC, Kaufman DB, Shea LD, Lowe WL (2006) Transplantation 82(4): 452-9
    › Primary publication · 16926587 (PubMed) · PMC2648394 (PubMed Central)
29. H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis. Pozzi A, Coffa S, Bulus N, Zhu W, Chen D, Chen X, Mernaugh G, Su Y, Cai S, Singh A, Brissova M, Zent R (2006) Mol Biol Cell 17(4): 2046-56
    › Primary publication · 16467383 (PubMed) · PMC1415315 (PubMed Central)
30. Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, Harlan DM, Powers AC (2005) J Histochem Cytochem 53(9): 1087-97
    › Primary publication · 15923354 (PubMed)
31. Assessment of pancreatic islet mass after islet transplantation using in vivo bioluminescence imaging. Fowler M, Virostko J, Chen Z, Poffenberger G, Radhika A, Brissova M, Shiota M, Nicholson WE, Shi Y, Hirshberg B, Harlan DM, Jansen ED, Powers AC (2005) Transplantation 79(7): 768-76
    › Primary publication · 15818318 (PubMed)
32. Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis. Brissova M, Blaha M, Spear C, Nicholson W, Radhika A, Shiota M, Charron MJ, Wright CV, Powers AC (2005) Am J Physiol Endocrinol Metab 288(4): E707-14
    › Primary publication · 15562255 (PubMed)
33. Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets. Brissova M, Fowler M, Wiebe P, Shostak A, Shiota M, Radhika A, Lin PC, Gannon M, Powers AC (2004) Diabetes 53(5): 1318-25
    › Primary publication · 15111502 (PubMed)
34. Assessment of insulin secretion in the mouse. Brissova M, Nicholson WE, Shiota M, Powers AC (2003) Methods Mol Med : 23-45
    › Primary publication · 12619713 (PubMed)
35. Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion. Brissova M, Shiota M, Nicholson WE, Gannon M, Knobel SM, Piston DW, Wright CV, Powers AC (2002) J Biol Chem 277(13): 11225-32
    › Primary publication · 11781323 (PubMed)
36. Permeability assessment of capsules for islet transplantation. Powers AC, Brissová M, Lacík I, Anilkumar AV, Shahrokhi K, Wang TG (1997) Ann N Y Acad Sci : 208-16
    › Primary publication · 9616712 (PubMed)
37. Control and measurement of permeability for design of microcapsule cell delivery system. Brissová M, Lacík I, Powers AC, Anilkumar AV, Wang T (1998) J Biomed Mater Res 39(1): 61-70
    › Primary publication · 9429097 (PubMed)
38. New capsule with tailored properties for the encapsulation of living cells. Lacík I, Brissová M, Anilkumar AV, Powers AC, Wang T (1998) J Biomed Mater Res 39(1): 52-60
    › Primary publication · 9429096 (PubMed)
39. An encapsulation system for the immunoisolation of pancreatic islets. Wang T, Lacík I, Brissová M, Anilkumar AV, Prokop A, Hunkeler D, Green R, Shahrokhi K, Powers AC (1997) Nat Biotechnol 15(4): 358-62
    › Primary publication · 9094138 (PubMed)
40. Evaluation of microcapsule permeability via inverse size exclusion chromatography. Brissová M, Petro M, Lacík I, Powers AC, Wang T (1996) Anal Biochem 242(1): 104-11
    › Primary publication · 8923972 (PubMed)
41. Study on the thermal stability of alpha-amylase modified by maleic anhydride copolymer. Brissová M, Augustín J, Simonetti M (1994) Int J Biol Macromol 16(3): 131-5
    › Primary publication · 7981159 (PubMed)

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