None provided


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. The relationship between pulmonary artery wedge pressure and pulmonary blood volume derived from contrast echocardiography: A proof-of-concept study. Monahan K, Lenihan D, Brittain EL, Saliba L, Piana RN, Robison LL, Hudson MM, Armstrong GT (2018) Echocardiography 35(9): 1266-1270
    › Primary publication · 29756230 (PubMed) · PMC6168381 (PubMed Central)
  2. Clinical Features Associated With Nascent Left Ventricular Diastolic Dysfunction in a Population Aged 40 to 55 Years. Mosley JD, Levinson RT, Brittain EL, Gupta DK, Farber-Eger E, Shaffer CM, Denny JC, Roden DM, Wells QS (2018) Am J Cardiol 121(12): 1552-1557
    › Primary publication · 29627106 (PubMed) · PMC5975107 (PubMed Central)
  3. Update in Pulmonary Vascular Disease 2016 and 2017. Brittain EL, Thennapan T, Maron BA, Chan SY, Austin ED, Spiekerkoetter E, Bogaard HJ, Guignabert C, Paulin R, Machado RF, Yu PB (2018) Am J Respir Crit Care Med 198(1): 13-23
    › Primary publication · 29533671 (PubMed) · PMC6034126 (PubMed Central)
  4. Autonomic Nervous System in Pulmonary Arterial Hypertension: Time to Rest and Digest. Hemnes AR, Brittain EL (2018) Circulation 137(9): 925-927
    › Primary publication · 29483171 (PubMed) · PMC5830155 (PubMed Central)
  5. Racial differences in patients referred for right heart catheterization and risk of pulmonary hypertension. Yang BQ, Assad TR, O'Leary JM, Xu M, Halliday SJ, D'Amico RW, Farber-Eger EH, Wells QS, Hemnes AR, Brittain EL (2018) Pulm Circ 8(2): 2045894018764273
    › Primary publication · 29480090 (PubMed) · PMC5858628 (PubMed Central)
  6. A Metabolic Basis for Endothelial-to-Mesenchymal Transition. Xiong J, Kawagishi H, Yan Y, Liu J, Wells QS, Edmunds LR, Fergusson MM, Yu ZX, Rovira II, Brittain EL, Wolfgang MJ, Jurczak MJ, Fessel JP, Finkel T (2018) Mol Cell 69(4): 689-698.e7
    › Primary publication · 29429925 (PubMed) · PMC5816688 (PubMed Central)
  7. Diabetes Mellitus Associates with Increased Right Ventricular Afterload and Remodeling in Pulmonary Arterial Hypertension. Whitaker ME, Nair V, Sinari S, Dherange PA, Natarajan B, Trutter L, Brittain EL, Hemnes AR, Austin ED, Patel K, Black SM, Garcia JGN, Yuan Md PhD JX, Vanderpool RR, Rischard F, Makino A, Bedrick EJ, Desai AA (2018) Am J Med 131(6): 702.e7-702.e13
    › Primary publication · 29421689 (PubMed) · PMC5963998 (PubMed Central)
  8. Redefining pulmonary hypertension. Maron BA, Brittain EL, Choudhary G, Gladwin MT (2018) Lancet Respir Med 6(3): 168-170
    › Primary publication · 29269004 (PubMed)
  9. The transpulmonary ratio of endothelin 1 is elevated in patients with preserved left ventricular ejection fraction and combined pre- and post-capillary pulmonary hypertension. Meoli DF, Su YR, Brittain EL, Robbins IM, Hemnes AR, Monahan K (2018) Pulm Circ 8(1): 2045893217745019
    › Primary publication · 29251543 (PubMed) · PMC5764145 (PubMed Central)
  10. Increased Echocardiographic Pulmonary Pressure in HIV-infected and -uninfected Individuals in the Veterans Aging Cohort Study. Brittain EL, Duncan MS, Chang J, Patterson OV, DuVall SL, Brandt CA, So-Armah KA, Goetz M, Akgun K, Crothers K, Zola C, Kim J, Gibert C, Pisani M, Morris A, Hsue P, Tindle HA, Justice A, Freiberg M (2018) Am J Respir Crit Care Med 197(7): 923-932
    › Primary publication · 29131651 (PubMed) · PMC6020408 (PubMed Central)
  11. Prognostic Effect and Longitudinal Hemodynamic Assessment of Borderline Pulmonary Hypertension. Assad TR, Maron BA, Robbins IM, Xu M, Huang S, Harrell FE, Farber-Eger EH, Wells QS, Choudhary G, Hemnes AR, Brittain EL (2017) JAMA Cardiol 2(12): 1361-1368
    › Primary publication · 29071338 (PubMed) · PMC5814998 (PubMed Central)
  12. Thermodilution vs Estimated Fick Cardiac Output Measurement in Clinical Practice: An Analysis of Mortality From the Veterans Affairs Clinical Assessment, Reporting, and Tracking (VA CART) Program and Vanderbilt University. Opotowsky AR, Hess E, Maron BA, Brittain EL, BarĂ³n AE, Maddox TM, Alshawabkeh LI, Wertheim BM, Xu M, Assad TR, Rich JD, Choudhary G, Tedford RJ (2017) JAMA Cardiol 2(10): 1090-1099
    › Primary publication · 28877293 (PubMed) · PMC5710449 (PubMed Central)
  13. Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects. Chen X, Austin ED, Talati M, Fessel JP, Farber-Eger EH, Brittain EL, Hemnes AR, Loyd JE, West J (2017) Eur Respir J 50(2)
    › Primary publication · 28775043 (PubMed) · PMC6532788 (PubMed Central)
  14. Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension. Egnatchik RA, Brittain EL, Shah AT, Fares WH, Ford HJ, Monahan K, Kang CJ, Kocurek EG, Zhu S, Luong T, Nguyen TT, Hysinger E, Austin ED, Skala MC, Young JD, Roberts LJ, Hemnes AR, West J, Fessel JP (2017) Pulm Circ 7(1): 186-199
    › Primary publication · 28680578 (PubMed) · PMC5448547 (PubMed Central)
  15. Kidney dysfunction in patients with pulmonary arterial hypertension. Nickel NP, O'Leary JM, Brittain EL, Fessel JP, Zamanian RT, West JD, Austin ED (2017) Pulm Circ 7(1): 38-54
    › Primary publication · 28680564 (PubMed) · PMC5448543 (PubMed Central)
  16. Pulmonary hypertension in patients with chronic kidney disease: invasive hemodynamic etiology and outcomes. O'Leary JM, Assad TR, Xu M, Birdwell KA, Farber-Eger E, Wells QS, Hemnes AR, Brittain EL (2017) Pulm Circ 7(3): 674-683
    › Primary publication · 28660793 (PubMed) · PMC5841902 (PubMed Central)
  17. Echocardiographic Pulmonary Artery Systolic Pressure in the Coronary Artery Risk Development in Young Adults (CARDIA) Study: Associations With Race and Metabolic Dysregulation. Brittain EL, Nwabuo C, Xu M, Gupta DK, Hemnes AR, Moreira HT, De Vasconcellos HD, Terry JG, Carr JJ, Lima JA (2017) J Am Heart Assoc 6(4)
    › Primary publication · 28360228 (PubMed) · PMC5533013 (PubMed Central)
  18. End-Tidal Carbon Dioxide as a Prognostic Feature in Pulmonary Arterial Hypertension. Welch CE, Brittain EL, Newman AL, Robbins IM, Pugh ME, Newman JH, Hemnes AR (2017) Ann Am Thorac Soc 14(6): 896-902
    › Primary publication · 28345964 (PubMed) · PMC6850742 (PubMed Central)
  19. Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension. Assad TR, Hemnes AR, Larkin EK, Glazer AM, Xu M, Wells QS, Farber-Eger EH, Sheng Q, Shyr Y, Harrell FE, Newman JH, Brittain EL (2016) J Am Coll Cardiol 68(23): 2525-2536
    › Primary publication · 27931609 (PubMed) · PMC5157701 (PubMed Central)
  20. Plasma hepatocyte growth factor is a novel marker of AL cardiac amyloidosis. Swiger KJ, Friedman EA, Brittain EL, Tomasek KA, Huang S, Su YR, Sawyer DB, Lenihan DJ (2016) Amyloid 23(4): 242-248
    › Primary publication · 27809600 (PubMed)
  21. Hemodynamic evidence of vascular remodeling in combined post- and precapillary pulmonary hypertension. Assad TR, Brittain EL, Wells QS, Farber-Eger EH, Halliday SJ, Doss LN, Xu M, Wang L, Harrell FE, Yu C, Robbins IM, Newman JH, Hemnes AR (2016) Pulm Circ 6(3): 313-21
    › Primary publication · 27683608 (PubMed) · PMC5019084 (PubMed Central)
  22. Integration of complex data sources to provide biologic insight into pulmonary vascular disease (2015 Grover Conference Series). Brittain EL, Chan SY (2016) Pulm Circ 6(3): 251-60
    › Primary publication · 27683602 (PubMed) · PMC5019078 (PubMed Central)
  23. Severity of pulmonary hypertension and obesity are not associated with worse functional outcomes after pulmonary thromboendarterectomy. Matthews DT, Le CN, Robbins IM, Petracek MR, Pugh ME, Brittain EL, Hemnes AR (2016) Pulm Circ 6(2): 174-80
    › Primary publication · 27252843 (PubMed) · PMC4869921 (PubMed Central)
  24. Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle. Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR (2016) Am J Respir Crit Care Med 194(6): 719-28
    › Primary publication · 27077479 (PubMed) · PMC5027228 (PubMed Central)
  25. Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension. Brittain EL, Talati M, Fessel JP, Zhu H, Penner N, Calcutt MW, West JD, Funke M, Lewis GD, Gerszten RE, Hamid R, Pugh ME, Austin ED, Newman JH, Hemnes AR (2016) Circulation 133(20): 1936-44
    › Primary publication · 27006481 (PubMed) · PMC4870107 (PubMed Central)
  26. Measurement of diffuse ventricular fibrosis with myocardial T1 in patients with atrial fibrillation. Montgomery JA, Abdallah W, Yoneda ZT, Brittain E, Aznaurov SG, Parvez B, Adkins K, Whalen SP, Estrada JC, Shen S, Crossley GH, Kanagasundram A, Saavedra P, Ellis CR, Lawson M, Darbar D, Shoemaker MB (2016) J Arrhythm 32(1): 51-6
    › Primary publication · 26949431 (PubMed) · PMC4759117 (PubMed Central)
  27. National Institutes of Health Career Development Awards for Cardiovascular Physician-Scientists: Recent Trends and Strategies for Success. Lindman BR, Tong CW, Carlson DE, Balke CW, Jackson EA, Madhur MS, Barac A, Abdalla M, Brittain EL, Desai N, Kates AM, Freeman AM, Mann DL (2015) J Am Coll Cardiol 66(16): 1816-1827
    › Primary publication · 26483107 (PubMed) · PMC4615587 (PubMed Central)
  28. The Diastolic Pressure Gradient Does Not-and Should Not-Predict Outcomes. Brittain EL, Assad TR, Hemnes AR, Newman JH (2015) JACC Heart Fail 3(10): 845
    › Primary publication · 26450004 (PubMed)
  29. Right ventricular protein expression profile in end-stage heart failure. Su YR, Chiusa M, Brittain E, Hemnes AR, Absi TS, Lim CC, Di Salvo TG (2015) Pulm Circ 5(3): 481-97
    › Primary publication · 26401249 (PubMed) · PMC4556499 (PubMed Central)
  30. Letter by Mosley Regarding Article, "Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat". Mosley JD, Brittain EL, Loyd JE, Denny JC, Austin ED, Larkin EK (2015) Circ Res 117(6): e56-7
    › Primary publication · 26316607 (PubMed) · PMC4557206 (PubMed Central)
  31. Right ventricular long noncoding RNA expression in human heart failure. Di Salvo TG, Guo Y, Su YR, Clark T, Brittain E, Absi T, Maltais S, Hemnes A (2015) Pulm Circ 5(1): 135-61
    › Primary publication · 25992278 (PubMed) · PMC4405709 (PubMed Central)
  32. Right ventricular myocardial biomarkers in human heart failure. di Salvo TG, Yang KC, Brittain E, Absi T, Maltais S, Hemnes A (2015) J Card Fail 21(5): 398-411
    › Primary publication · 25725476 (PubMed) · PMC6482959 (PubMed Central)
  33. An Inflection Point Method for the Determination of Pulmonary Transit Time From Contrast Echocardiography. Boronyak SM, Monahan K, Brittain EL, Merryman WD (2015) IEEE Trans Biomed Eng 62(7): 1853-61
    › Primary publication · 25706506 (PubMed)
  34. Feasibility and Diagnostic Potential of Pulmonary Transit Time Measurement by Contrast Echocardiography: A Pilot Study. Brittain EL, Doss LN, Saliba L, Irani W, Byrd BF, Monahan K (2015) Echocardiography 32(10): 1564-71
    › Primary publication · 25682691 (PubMed) · PMC4536186 (PubMed Central)
  35. Vasodilator-responsive idiopathic pulmonary arterial hypertension: evidence for a new disease? Brittain EL, Hemnes AR (2015) Ann Intern Med 162(2): 148-9
    › Primary publication · 25599353 (PubMed) · PMC5679119 (PubMed Central)
  36. Prognostic value of acute vasodilator response in pulmonary arterial hypertension: beyond the "classic" responders. Halliday SJ, Hemnes AR, Robbins IM, Pugh ME, Zhao DX, Piana RN, Fong PP, Brittain EL (2015) J Heart Lung Transplant 34(3): 312-8
    › Primary publication · 25577565 (PubMed) · PMC4380573 (PubMed Central)
  37. Effect of acute arteriolar vasodilation on capacitance and resistance in pulmonary arterial hypertension. Newman JH, Brittain EL, Robbins IM, Hemnes AR (2015) Chest 147(4): 1080-1085
    › Primary publication · 25340330 (PubMed) · PMC4388116 (PubMed Central)
  38. Impact of diabetes on survival and right ventricular compensation in pulmonary arterial hypertension. Benson L, Brittain EL, Pugh ME, Austin ED, Fox K, Wheeler L, Robbins IM, Hemnes AR (2014) Pulm Circ 4(2): 311-8
    › Primary publication · 25006450 (PubMed) · PMC4070784 (PubMed Central)
  39. Elevation of plasma cell-free hemoglobin in pulmonary arterial hypertension. Brittain EL, Janz DR, Austin ED, Bastarache JA, Wheeler LA, Ware LB, Hemnes AR (2014) Chest 146(6): 1478-1485
    › Primary publication · 24945582 (PubMed) · PMC4251612 (PubMed Central)
  40. Challenges facing early career academic cardiologists. Tong CW, Ahmad T, Brittain EL, Bunch TJ, Damp JB, Dardas T, Hijar A, Hill JA, Hilliard AA, Houser SR, Jahangir E, Kates AM, Kim D, Lindman BR, Ryan JJ, Rzeszut AK, Sivaram CA, Valente AM, Freeman AM (2014) J Am Coll Cardiol 63(21): 2199-208
    › Primary publication · 24703919 (PubMed) · PMC4306449 (PubMed Central)
  41. Shorter survival in familial versus idiopathic pulmonary arterial hypertension is associated with hemodynamic markers of impaired right ventricular function. Brittain EL, Pugh ME, Wheeler LA, Robbins IM, Loyd JE, Newman JH, Larkin EK, Austin ED, Hemnes AR (2013) Pulm Circ 3(3): 589-98
    › Primary publication · 24618543 (PubMed) · PMC4070798 (PubMed Central)
  42. One generation's "junk" is another's treasure: the emerging role of microRNAs as therapeutic targets. Brittain EL, Hemnes AR (2014) J Heart Lung Transplant 33(3): 233-4
    › Primary publication · 24462555 (PubMed) · PMC4837650 (PubMed Central)
  43. Minimally invasive fibrillating mitral valve replacement for patients with advanced cardiomyopathy: a safe and effective approach to treat a complex problem. Brittain EL, Goyal SK, Sample MA, Leacche M, Absi TS, Papa F, Churchwell KB, Ball S, Byrne JG, Maltais S, Petracek MR, Mendes L (2014) J Thorac Cardiovasc Surg 148(5): 2045-2051.e1
    › Primary publication · 24332110 (PubMed) · PMC4050032 (PubMed Central)
  44. Echocardiographic assessment of the right heart in mice. Brittain E, Penner NL, West J, Hemnes A (2013) J Vis Exp (81)
    › Primary publication · 24326586 (PubMed) · PMC3992116 (PubMed Central)
  45. High prevalence of occult pulmonary venous hypertension revealed by fluid challenge in pulmonary hypertension. Robbins IM, Hemnes AR, Pugh ME, Brittain EL, Zhao DX, Piana RN, Fong PP, Newman JH (2014) Circ Heart Fail 7(1): 116-22
    › Primary publication · 24297689 (PubMed) · PMC3934572 (PubMed Central)
  46. Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension. Hemnes AR, Brittain EL, Trammell AW, Fessel JP, Austin ED, Penner N, Maynard KB, Gleaves L, Talati M, Absi T, Disalvo T, West J (2014) Am J Respir Crit Care Med 189(3): 325-34
    › Primary publication · 24274756 (PubMed) · PMC3977729 (PubMed Central)
  47. Predictors of diastolic-to-wedge gradient in patients evaluated for pulmonary hypertension. Brittain EL, Pugh ME, Wang L, Newman AL, Robbins IM, Newman JH, Hemnes AR (2013) PLoS One 8(10): e76461
    › Primary publication · 24124561 (PubMed) · PMC3790694 (PubMed Central)
  48. Prostanoids but not oral therapies improve right ventricular function in pulmonary arterial hypertension. Brittain EL, Pugh ME, Wheeler LA, Robbins IM, Loyd JE, Newman JH, Austin ED, Hemnes AR (2013) JACC Heart Fail 1(4): 300-307
    › Primary publication · 24015376 (PubMed) · PMC3763862 (PubMed Central)
  49. Hemodynamic improvement of pulmonary arterial hypertension after bariatric surgery: potential role for metabolic regulation. Pugh ME, Newman JH, Williams DB, Brittain E, Robbins IM, Hemnes AR (2013) Diabetes Care 36(3): e32-3
    › Primary publication · 23431096 (PubMed) · PMC3579352 (PubMed Central)
  50. Acute improvement in right ventricular function after treatment of presumed massive pulmonary embolism with thrombolytics. Brittain EL, Janz DR, Monahan KJ, Sevin CM (2012) Pulm Circ 2(4): 522-4
    › Primary publication · 23372938 (PubMed) · PMC3555424 (PubMed Central)
  51. Right ventricular plasticity and functional imaging. Brittain EL, Hemnes AR, Keebler M, Lawson M, Byrd BF, Disalvo T (2012) Pulm Circ 2(3): 309-26
    › Primary publication · 23130100 (PubMed) · PMC3487300 (PubMed Central)