My previous and ongoing research projects focus on overcoming the real world limitations of MRI that hinder research and clinical applications. I seek solutions to problems such as motion corruption, static field and radio frequency field inhomogeneity, long acquisition times, field of view limitations, and the qualitative nature of most MRI methods. Strategies to overcome these challenges include both hardware and software solutions, alternative data acquisition and reconstruction methods, novel MRI pulse sequences, quantitative imaging methods and associated post-processing tools.


Complete List of 50 Peer-Reviewed Published Works Reported by NCBI


The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease. Damon BM, Li K, Dortch RD, Welch EB, Park JH, Buck AK, Towse TF, Does MD, Gochberg DF, Bryant ND (2016) J Vis Exp (118)
    › Primary publication · 28060254 (PubMed) · PMC5226425 (PubMed Central)
  2. Fat-water MRI of a diet-induced obesity mouse model at 15.2T. Ong HH, Webb CD, Gruen ML, Hasty AH, Gore JC, Welch EB (2016) J Med Imaging (Bellingham) 3(2): 026002
    › Primary publication · 27226976 (PubMed) · PMC4877437 (PubMed Central)
  3. Characterizing active and inactive brown adipose tissue in adult humans using PET-CT and MR imaging. Gifford A, Towse TF, Walker RC, Avison MJ, Welch EB (2016) Am J Physiol Endocrinol Metab 311(1): E95-E104
    › Primary publication · 27166284 (PubMed) · PMC4967150 (PubMed Central)
  4. Multisite, multivendor validation of the accuracy and reproducibility of proton-density fat-fraction quantification at 1.5T and 3T using a fat-water phantom. Hernando D, Sharma SD, Aliyari Ghasabeh M, Alvis BD, Arora SS, Hamilton G, Pan L, Shaffer JM, Sofue K, Szeverenyi NM, Welch EB, Yuan Q, Bashir MR, Kamel IR, Rice MJ, Sirlin CB, Yokoo T, Reeder SB (2017) Magn Reson Med 77(4): 1516-1524
    › Primary publication · 27080068 (PubMed) · PMC4835219 (PubMed Central)
  5. Incorporating dixon multi-echo fat water separation for novel quantitative magnetization transfer of the human optic nerve in vivo. Smith AK, Dortch RD, Dethrage LM, Lyttle BD, Kang H, Welch EB, Smith SA (2017) Magn Reson Med 77(2): 707-716
    › Primary publication · 27037720 (PubMed) · PMC5045743 (PubMed Central)
  6. Correlations between quantitative fat-water magnetic resonance imaging and computed tomography in human subcutaneous white adipose tissue. Gifford A, Walker RC, Towse TF, Brian Welch E (2015) J Med Imaging (Bellingham) 2(4): 046001
    › Primary publication · 26702407 (PubMed) · PMC4684077 (PubMed Central)
  7. Imaging methods for analyzing body composition in human obesity and cardiometabolic disease. Seabolt LA, Welch EB, Silver HJ (2015) Ann N Y Acad Sci : 41-59
    › Primary publication · 26250623 (PubMed)
  8. Whole-body continuously moving table fat-water MRI with dynamic B0 shimming at 3 Tesla. Sengupta S, Smith DS, Gifford A, Welch EB (2016) Magn Reson Med 76(1): 183-90
    › Primary publication · 26198380 (PubMed) · PMC4775426 (PubMed Central)
  9. DCEMRI.jl: a fast, validated, open source toolkit for dynamic contrast enhanced MRI analysis. Smith DS, Li X, Arlinghaus LR, Yankeelov TE, Welch EB (2015) PeerJ : e909
    › Primary publication · 25922795 (PubMed) · PMC4411523 (PubMed Central)
  10. 7T MRI-Histologic Correlation Study of Low Specific Absorption Rate T2-Weighted GRASE Sequences in the Detection of White Matter Involvement in Multiple Sclerosis. Bagnato F, Hametner S, Pennell D, Dortch R, Dula AN, Pawate S, Smith SA, Lassmann H, Gore JC, Welch EB (2015) J Neuroimaging 25(3): 370-8
    › Primary publication · 25898858 (PubMed) · PMC6934161 (PubMed Central)
  11. Human brown adipose tissue depots automatically segmented by positron emission tomography/computed tomography and registered magnetic resonance images. Gifford A, Towse TF, Walker RC, Avison MJ, Welch EB (2015) J Vis Exp (96)
    › Primary publication · 25741672 (PubMed) · PMC4354647 (PubMed Central)
  12. Detection of microcalcifications by characteristic magnetic susceptibility effects using MR phase image cross-correlation analysis. Baheza RA, Welch EB, Gochberg DF, Sanders M, Harvey S, Gore JC, Yankeelov TE (2015) Med Phys 42(3): 1436-52
    › Primary publication · 25735297 (PubMed) · PMC4344475 (PubMed Central)
  13. Continuously moving table MRI with golden angle radial sampling. Sengupta S, Smith DS, Welch EB (2015) Magn Reson Med 74(6): 1690-7
    › Primary publication · 25461600 (PubMed) · PMC4452468 (PubMed Central)
  14. Multi-parametric MRI characterization of healthy human thigh muscles at 3.0 T - relaxation, magnetization transfer, fat/water, and diffusion tensor imaging. Li K, Dortch RD, Welch EB, Bryant ND, Buck AK, Towse TF, Gochberg DF, Does MD, Damon BM, Park JH (2014) NMR Biomed 27(9): 1070-84
    › Primary publication · 25066274 (PubMed) · PMC4153695 (PubMed Central)
  15. Potential of compressed sensing in quantitative MR imaging of cancer. Smith DS, Li X, Abramson RG, Quarles CC, Yankeelov TE, Welch EB (2013) Cancer Imaging 13(4): 633-44
    › Primary publication · 24434808 (PubMed) · PMC3893904 (PubMed Central)
  16. Automating PACS Quality Control with the Vanderbilt Image Processing Enterprise Resource. Esparza ML, Welch EB, Landman BA (2012) Proc SPIE Int Soc Opt Eng
    › Primary publication · 24357910 (PubMed) · PMC3865245 (PubMed Central)
  17. Prospective real-time head motion correction using inductively coupled wireless NMR probes. Sengupta S, Tadanki S, Gore JC, Welch EB (2014) Magn Reson Med 72(4): 971-85
    › Primary publication · 24243810 (PubMed) · PMC4304771 (PubMed Central)
  18. Comparison of gross body fat-water magnetic resonance imaging at 3 Tesla to dual-energy X-ray absorptiometry in obese women. Silver HJ, Niswender KD, Kullberg J, Berglund J, Johansson L, Bruvold M, Avison MJ, Welch EB (2013) Obesity (Silver Spring) 21(4): 765-74
    › Primary publication · 23712980 (PubMed) · PMC3500572 (PubMed Central)
  19. Canine body composition quantification using 3 tesla fat-water MRI. Gifford A, Kullberg J, Berglund J, Malmberg F, Coate KC, Williams PE, Cherrington AD, Avison MJ, Welch EB (2014) J Magn Reson Imaging 39(2): 485-91
    › Primary publication · 23596090 (PubMed) · PMC3735857 (PubMed Central)
  20. Medical imaging: Sleuthing tissue fingerprints. Welch EB (2013) Nature 495(7440): 184-5
    › Primary publication · 23486057 (PubMed)
  21. Quantitative effects of inclusion of fat on muscle diffusion tensor MRI measurements. Williams SE, Heemskerk AM, Welch EB, Li K, Damon BM, Park JH (2013) J Magn Reson Imaging 38(5): 1292-7
    › Primary publication · 23418124 (PubMed) · PMC3664247 (PubMed Central)
  22. Visualizing iron in multiple sclerosis. Bagnato F, Hametner S, Welch EB (2013) Magn Reson Imaging 31(3): 376-84
    › Primary publication · 23347601 (PubMed) · PMC4776767 (PubMed Central)
  23. Real-Time Compressive Sensing MRI Reconstruction Using GPU Computing and Split Bregman Methods. Smith DS, Gore JC, Yankeelov TE, Welch EB (2012) Int J Biomed Imaging : 864827
    › Primary publication · 22481908 (PubMed) · PMC3296267 (PubMed Central)
  24. Early prediction of the response of breast tumors to neoadjuvant chemotherapy using quantitative MRI and machine learning. Mani S, Chen Y, Arlinghaus LR, Li X, Chakravarthy AB, Bhave SR, Welch EB, Levy MA, Yankeelov TE (2011) AMIA Annu Symp Proc : 868-77
    › Primary publication · 22195145 (PubMed) · PMC3243164 (PubMed Central)
  25. Statistical comparison of dynamic contrast-enhanced MRI pharmacokinetic models in human breast cancer. Li X, Welch EB, Chakravarthy AB, Xu L, Arlinghaus LR, Farley J, Mayer IA, Kelley MC, Meszoely IM, Means-Powell J, Abramson VG, Grau AM, Gore JC, Yankeelov TE (2012) Magn Reson Med 68(1): 261-71
    › Primary publication · 22127821 (PubMed) · PMC3291742 (PubMed Central)
  26. Robustness of quantitative compressive sensing MRI: the effect of random undersampling patterns on derived parameters for DCE- and DSC-MRI. Smith DS, Li X, Gambrell JV, Arlinghaus LR, Quarles CC, Yankeelov TE, Welch EB (2012) IEEE Trans Med Imaging 31(2): 504-11
    › Primary publication · 22010146 (PubMed) · PMC3289060 (PubMed Central)
  27. Integration of diffusion-weighted MRI data and a simple mathematical model to predict breast tumor cellularity during neoadjuvant chemotherapy. Atuegwu NC, Arlinghaus LR, Li X, Welch EB, Chakravarthy BA, Gore JC, Yankeelov TE (2011) Magn Reson Med 66(6): 1689-96
    › Primary publication · 21956404 (PubMed) · PMC3218213 (PubMed Central)
  28. Integrating Medical Imaging Analyses through a High-throughput Bundled Resource Imaging System. Covington K, Welch EB, Jeong HK, Landman BA (2011) Proc SPIE Int Soc Opt Eng
    › Primary publication · 21841899 (PubMed) · PMC3154704 (PubMed Central)
  29. A novel AIF tracking method and comparison of DCE-MRI parameters using individual and population-based AIFs in human breast cancer. Li X, Welch EB, Arlinghaus LR, Chakravarthy AB, Xu L, Farley J, Loveless ME, Mayer IA, Kelley MC, Meszoely IM, Means-Powell JA, Abramson VG, Grau AM, Gore JC, Yankeelov TE (2011) Phys Med Biol 56(17): 5753-69
    › Primary publication · 21841212 (PubMed) · PMC3176673 (PubMed Central)
  30. Quantitative effects of using compressed sensing in dynamic contrast enhanced MRI. Smith DS, Welch EB, Li X, Arlinghaus LR, Loveless ME, Koyama T, Gore JC, Yankeelov TE (2011) Phys Med Biol 56(15): 4933-46
    › Primary publication · 21772079 (PubMed) · PMC3192434 (PubMed Central)
  31. Quantitative magnetization transfer imaging in human brain at 3 T via selective inversion recovery. Dortch RD, Li K, Gochberg DF, Welch EB, Dula AN, Tamhane AA, Gore JC, Smith SA (2011) Magn Reson Med 66(5): 1346-52
    › Primary publication · 21608030 (PubMed) · PMC3285505 (PubMed Central)
  32. On the relationship between the apparent diffusion coefficient and extravascular extracellular volume fraction in human breast cancer. Arlinghaus LR, Li X, Rahman AR, Welch EB, Xu L, Gore JC, Yankeelov TE (2011) Magn Reson Imaging 29(5): 630-8
    › Primary publication · 21531106 (PubMed) · PMC3100356 (PubMed Central)
  33. Motion correction in diffusion-weighted MRI of the breast at 3T. Arlinghaus LR, Welch EB, Chakravarthy AB, Xu L, Farley JS, Abramson VG, Grau AM, Kelley MC, Mayer IA, Means-Powell JA, Meszoely IM, Gore JC, Yankeelov TE (2011) J Magn Reson Imaging 33(5): 1063-70
    › Primary publication · 21509862 (PubMed) · PMC3081111 (PubMed Central)
  34. Software compensation of eddy current fields in multislice high order dynamic shimming. Sengupta S, Avison MJ, Gore JC, Brian Welch E (2011) J Magn Reson 210(2): 218-27
    › Primary publication · 21458339 (PubMed) · PMC3098125 (PubMed Central)
  35. Imaging body composition in obesity and weight loss: challenges and opportunities. Silver HJ, Welch EB, Avison MJ, Niswender KD (2010) Diabetes Metab Syndr Obes : 337-47
    › Primary publication · 21437103 (PubMed) · PMC3047979 (PubMed Central)
  36. Development of chemical exchange saturation transfer at 7 T. Dula AN, Asche EM, Landman BA, Welch EB, Pawate S, Sriram S, Gore JC, Smith SA (2011) Magn Reson Med 66(3): 831-8
    › Primary publication · 21432902 (PubMed) · PMC3156337 (PubMed Central)
  37. Dynamic B0 shimming at 7 T. Sengupta S, Welch EB, Zhao Y, Foxall D, Starewicz P, Anderson AW, Gore JC, Avison MJ (2011) Magn Reson Imaging 29(4): 483-96
    › Primary publication · 21398062 (PubMed) · PMC3078963 (PubMed Central)
  38. Current and future trends in magnetic resonance imaging assessments of the response of breast tumors to neoadjuvant chemotherapy. Arlinghaus LR, Li X, Levy M, Smith D, Welch EB, Gore JC, Yankeelov TE (2010) J Oncol
    › Primary publication · 20953332 (PubMed) · PMC2952974 (PubMed Central)
  39. Anterior cingulate and cerebellar GABA and Glu correlations measured by ¹H J-difference spectroscopy. Waddell KW, Zanjanipour P, Pradhan S, Xu L, Welch EB, Joers JM, Martin PR, Avison MJ, Gore JC (2011) Magn Reson Imaging 29(1): 19-24
    › Primary publication · 20884148 (PubMed) · PMC3005886 (PubMed Central)
  40. Validation of an algorithm for the nonrigid registration of longitudinal breast MR images using realistic phantoms. Li X, Dawant BM, Welch EB, Chakravarthy AB, Xu L, Mayer I, Kelley M, Meszoely I, Means-Powell J, Gore JC, Yankeelov TE (2010) Med Phys 37(6): 2541-52
    › Primary publication · 20632566 (PubMed) · PMC2881925 (PubMed Central)
  41. Effect of MR distortion on targeting for deep-brain stimulation. Balachandran R, Welch EB, Dawant BM, Fitzpatrick JM (2010) IEEE Trans Biomed Eng 57(7): 1729-35
    › Primary publication · 20388592 (PubMed) · PMC3114439 (PubMed Central)
  42. Practical considerations for the design of sparse-spokes pulses. Jankiewicz M, Zeng H, Moore JE, Anderson AW, Avison MJ, Welch EB, Gore JC (2010) J Magn Reson 203(2): 294-304
    › Primary publication · 20172754 (PubMed) · PMC2853049 (PubMed Central)
  43. The sign convention for phase values on different vendor systems: definition and implications for susceptibility-weighted imaging. Hagberg GE, Welch EB, Greiser A (2010) Magn Reson Imaging 28(2): 297-300
    › Primary publication · 19699598 (PubMed)
  44. Temporal sampling requirements for reference region modeling of DCE-MRI data in human breast cancer. Planey CR, Welch EB, Xu L, Chakravarthy AB, Gatenby JC, Freehardt D, Mayer I, Meszeoly I, Kelley M, Means-Powell J, Gore JC, Yankeelov TE (2009) J Magn Reson Imaging 30(1): 121-34
    › Primary publication · 19557727 (PubMed) · PMC2782711 (PubMed Central)
  45. A nonrigid registration algorithm for longitudinal breast MR images and the analysis of breast tumor response. Li X, Dawant BM, Welch EB, Chakravarthy AB, Freehardt D, Mayer I, Kelley M, Meszoely I, Gore JC, Yankeelov TE (2009) Magn Reson Imaging 27(9): 1258-70
    › Primary publication · 19525078 (PubMed) · PMC2763059 (PubMed Central)
  46. High-resolution 7T MRI of the human hippocampus in vivo. Thomas BP, Welch EB, Niederhauser BD, Whetsell WO, Anderson AW, Gore JC, Avison MJ, Creasy JL (2008) J Magn Reson Imaging 28(5): 1266-72
    › Primary publication · 18972336 (PubMed) · PMC2669832 (PubMed Central)
  47. Implementation of a semi-automated post-processing system for parametric MRI mapping of human breast cancer. Lee RE, Welch EB, Cobb JG, Sinha T, Gore JC, Yankeelov TE (2009) J Digit Imaging 22(4): 424-36
    › Primary publication · 18446412 (PubMed) · PMC3043701 (PubMed Central)
  48. Interscan registration using navigator echoes. Welch EB, Manduca A, Grimm RC, Jack CR (2004) Magn Reson Med 52(6): 1448-52
    › Primary publication · 15562488 (PubMed)
  49. Self-navigated motion correction using moments of spatial projections in radial MRI. Welch EB, Rossman PJ, Felmlee JP, Manduca A (2004) Magn Reson Med 52(2): 337-45
    › Primary publication · 15282816 (PubMed)
  50. Motion correction using the k-space phase difference of orthogonal acquisitions. Welch EB, Felmlee JP, Ehman RL, Manduca A (2002) Magn Reson Med 48(1): 147-56
    › Primary publication · 12111942 (PubMed)
  51. Spherical navigator echoes for full 3D rigid body motion measurement in MRI. Welch EB, Manduca A, Grimm RC, Ward HA, Jack CR (2002) Magn Reson Med 47(1): 32-41
    › Primary publication · 11754440 (PubMed)
  52. Autocorrection in MR imaging: adaptive motion correction without navigator echoes. Manduca A, McGee KP, Welch EB, Felmlee JP, Grimm RC, Ehman RL (2000) Radiology 215(3): 904-9
    › Primary publication · 10831720 (PubMed)