Jean-Philippe (JP) Cartailler is the Director of Informatics for the Vanderbilt Center for Stem Cell Biology and also directs Creative Data Solutions (CDS), a Vanderbilt shared resource.

His current focus is on bioinformatics, research informatics, data visualization and software/database engineering. CDS also manages Labnodes, Vanderbilt's research network application.

Past projects of significance include:

  • Beta Cell Biology Consortium - Oversight and management of informatics development and integration of genomics/bioinformatics component
  • NIDDK Consortium Interconnectivity Network (dkCOIN, now dkNET) - Led a multi-consortium pilot program with the goal of aggregating scientific data generated by team science initiatives. 
  • Vanderbilt Genome Sciences Resource (now VANTAGE) - Informatics and LIMS development and implementation.



The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Quantitative Analysis of Adenosine-to-Inosine RNA Editing. Malik TN, Cartailler JP, Emeson RB (2021) Methods Mol Biol : 97-111
    › Primary publication · 32729077 (PubMed) · PMC8208106 (PubMed Central)
  2. Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells. Osipovich AB, Stancill JS, Cartailler JP, Dudek KD, Magnuson MA (2020) Diabetes 69(7): 1476-1491
    › Primary publication · 32332159 (PubMed) · PMC7809715 (PubMed Central)
  3. Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences. Stancill JS, Osipovich AB, Cartailler JP, Magnuson MA (2019) Am J Physiol Endocrinol Metab 316(2): E196-E209
    › Primary publication · 30532991 (PubMed) · PMC6397359 (PubMed Central)
  4. Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca-Regulated Genes. Stancill JS, Cartailler JP, Clayton HW, O'Connor JT, Dickerson MT, Dadi PK, Osipovich AB, Jacobson DA, Magnuson MA (2017) Diabetes 66(8): 2175-2187
    › Primary publication · 28550109 (PubMed) · PMC5521870 (PubMed Central)
  5. Research resource: dkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to aggregate research resources generated by multiple research consortia. McKenna NJ, Howard CL, Aufiero M, Easton-Marks J, Steffen DL, Becnel LB, Magnuson MA, McIndoe RA, Cartailler JP (2012) Mol Endocrinol 26(10): 1675-81
    › Primary publication · 22734043 (PubMed) · PMC3458218 (PubMed Central)
  6. A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes. Vanacore RM, Ham AJ, Cartailler JP, Sundaramoorthy M, Todd P, Pedchenko V, Sado Y, Borza DB, Hudson BG (2008) J Biol Chem 283(33): 22737-48
    › Primary publication · 18499662 (PubMed) · PMC2504875 (PubMed Central)
  7. Molecular recognition in the assembly of collagens: terminal noncollagenous domains are key recognition modules in the formation of triple helical protomers. Khoshnoodi J, Cartailler JP, Alvares K, Veis A, Hudson BG (2006) J Biol Chem 281(50): 38117-21
    › Primary publication · 17082192 (PubMed)
  8. Mechanism of chain selection in the assembly of collagen IV: a prominent role for the alpha2 chain. Khoshnoodi J, Sigmundsson K, Cartailler JP, Bondar O, Sundaramoorthy M, Hudson BG (2006) J Biol Chem 281(9): 6058-69
    › Primary publication · 16373348 (PubMed)
  9. Strategies for the use of site-specific recombinases in genome engineering. Jones JR, Shelton KD, Magnuson MA (2005) Methods Mol Med : 245-57
    › Primary publication · 15542911 (PubMed)
  10. Structural and functional characterization of pi bulges and other short intrahelical deformations. Cartailler JP, Luecke H (2004) Structure 12(1): 133-44
    › Primary publication · 14725773 (PubMed)
  11. X-ray crystallographic analysis of lipid-protein interactions in the bacteriorhodopsin purple membrane. Cartailler JP, Luecke H (2003) Annu Rev Biophys Biomol Struct : 285-310
    › Primary publication · 12598369 (PubMed)
  12. Coupling photoisomerization of retinal to directional transport in bacteriorhodopsin. Luecke H, Schobert B, Cartailler JP, Richter HT, Rosengarth A, Needleman R, Lanyi JK (2000) J Mol Biol 300(5): 1237-55
    › Primary publication · 10903866 (PubMed)
  13. Annexins V and XII insert into bilayers at mildly acidic pH and form ion channels. Isas JM, Cartailler JP, Sokolov Y, Patel DR, Langen R, Luecke H, Hall JE, Haigler HT (2000) Biochemistry 39(11): 3015-22
    › Primary publication · 10715122 (PubMed)
  14. Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization. Cartailler JP, Haigler HT, Luecke H (2000) Biochemistry 39(10): 2475-83
    › Primary publication · 10704197 (PubMed)
  15. Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution. Luecke H, Schobert B, Richter HT, Cartailler JP, Lanyi JK (1999) Science 286(5438): 255-61
    › Primary publication · 10514362 (PubMed)