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Pam Uttz

Official Affiliation: Vanderbilt Center for Stem Cell Biology

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Assistant to Mark Magnuson, M.D.

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response. Yang X, Graff SM, Heiser CN, Ho KH, Chen B, Simmons AJ, Southard-Smith AN, David G, Jacobson DA, Kaverina I, Wright CVE, Lau KS, Gu G (2020) Diabetes 69(6): 1219-1231
    › Primary publication · 32245798 (PubMed)
  2. Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones. Iwafuchi M, Cuesta I, Donahue G, Takenaka N, Osipovich AB, Magnuson MA, Roder H, Seeholzer SH, Santisteban P, Zaret KS (2020) Nat Genet 52(4): 418-427
    › Primary publication · 32203463 (PubMed)
  3. The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function. Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R (2019) Diabetes 68(9): 1806-1818
    › Primary publication · 31201281 (PubMed) · PMC6702633 (PubMed Central)
  4. Point mutations in the PDX1 transactivation domain impair human β-cell development and function. Wang X, Sterr M, Ansarullah , Burtscher I, Böttcher A, Beckenbauer J, Siehler J, Meitinger T, Häring HU, Staiger H, Cernilogar FM, Schotta G, Irmler M, Beckers J, Wright CVE, Bakhti M, Lickert H (2019) Mol Metab : 80-97
    › Primary publication · 30930126 (PubMed) · PMC6531841 (PubMed Central)
  5. ROCK-nmMyoII, Notch and gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche. Bankaitis ED, Bechard ME, Gu G, Magnuson MA, Wright CVE (2018) Development 145(18)
    › Primary publication · 30126902 (PubMed) · PMC6176929 (PubMed Central)
  6. Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M (2018) Cell Rep 24(1): 79-94
    › Primary publication · 29972793 (PubMed)
  7. ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice. Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H (2018) Gastroenterology 155(1): 194-209.e2
    › Primary publication · 29604291 (PubMed)
  8. EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity. Löf-Öhlin ZM, Nyeng P, Bechard ME, Hess K, Bankaitis E, Greiner TU, Ameri J, Wright CV, Semb H (2017) Nat Cell Biol 19(11): 1313-1325
    › Primary publication · 29058721 (PubMed)
  9. A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry. Zhang J, Weinrich JAP, Russ JB, Comer JD, Bommareddy PK, DiCasoli RJ, Wright CVE, Li Y, van Roessel PJ, Kaltschmidt JA (2017) Cell Rep 21(3): 666-678
    › Primary publication · 29045835 (PubMed) · PMC5658202 (PubMed Central)
  10. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics. Pulley JM, Shirey-Rice JK, Lavieri RR, Jerome RN, Zaleski NM, Aronoff DM, Bastarache L, Niu X, Holroyd KJ, Roden DM, Skaar EP, Niswender CM, Marnett LJ, Lindsley CW, Ekstrom LB, Bentley AR, Bernard GR, Hong CC, Denny JC (2017) Assay Drug Dev Technol 15(3): 113-119
    › Primary publication · 28379727 (PubMed) · PMC5399743 (PubMed Central)
  11. Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function. Henley KD, Stanescu DE, Kropp PA, Wright CVE, Won KJ, Stoffers DA, Gannon M (2016) Cell Rep 15(12): 2637-2650
    › Primary publication · 27292642 (PubMed) · PMC4917419 (PubMed Central)
  12. Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma. Hover LD, Owens P, Munden AL, Wang J, Chambless LB, Hopkins CR, Hong CC, Moses HL, Abel TW (2016) Neuro Oncol 18(7): 928-38
    › Primary publication · 26683138 (PubMed) · PMC4896540 (PubMed Central)
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Contact Information

9465 MRB IV 2213 Garland Avenue
Nashville, TN 37232-0494
615-322-7006 (p)
615-322-6645 (f)
Email

Keywords & MeSH Terms

MeSH terms are retrieved from PubMed records. Learn more.

Key: MeSH Term Keyword

Animals Astrocytes Carcinogenesis Cell Differentiation Cell Line Cell Transformation, Neoplastic Databases, Genetic Diabetes Mellitus DNA-Binding Proteins DNA Helicases Drug Design Drug Repositioning Endocrine Cells Gene Expression Regulation, Developmental Gene Regulatory Networks Genetic Predisposition to Disease Hepatocyte Nuclear Factor 6 Homeostasis Insulin Insulin-Secreting Cells Mice, Knockout Molecular Chaperones Nerve Tissue Proteins Organogenesis Prosencephalon Protein Domains Protein Kinase C Proto-Oncogene Proteins p21(ras) Receptors, Notch Weaning