Profile

Jean-Philippe Cartailler is the Director of Informatics for the Vanderbilt Center for Stem Cell Biology.

He is involved in the daily activities of the Beta Cell Biology Consortium, which is coordinated out of Vanderbilt University. He has also led a multi-consortium team to develop the NIDDK Consortium Interconnectivity Network (dkCOIN) pilot program, with the goal of aggregating scientific data generated by team science initiatives.  He also spent two years working in informatics development and oversight of Vanderbilt's Genome Sciences Resource, now VANTAGE. his current efforts are focused on Labnodes, Vanderbilt's research network application and starting up a new Vanderbilt Shared Resource, Creative Data Solutions.

JP also had the privilege of working with:

  • Greg Baboolal
  • Chris Howard
  • Thomas Houfek
  • Jill Lindner
  • Josh Norman
  • James Tibbetts
  • Andrew Visser

 

Publications

The following timeline graph is generated from all co-authored publications.

Featured publications are shown below:

  1. Chronic β-Cell Depolarization Impairs β-Cell Identity by Disrupting a Network of Ca(2+)-Regulated Genes. Stancill JS, Cartailler JP, Clayton HW, O'Connor JT, Dickerson MT, Dadi PK, Osipovich AB, Jacobson DA, Magnuson MA (2017) Diabetes
    › Primary publication · 28550109 (PubMed)
  2. Research resource: dkCOIN, the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) consortium interconnectivity network: a pilot program to aggregate research resources generated by multiple research consortia. McKenna NJ, Howard CL, Aufiero M, Easton-Marks J, Steffen DL, Becnel LB, Magnuson MA, McIndoe RA, Cartailler JP (2012) Mol Endocrinol 26(10): 1675-81
    › Primary publication · 22734043 (PubMed) · PMC3458218 (PubMed Central)
  3. A role for collagen IV cross-links in conferring immune privilege to the Goodpasture autoantigen: structural basis for the crypticity of B cell epitopes. Vanacore RM, Ham AJ, Cartailler JP, Sundaramoorthy M, Todd P, Pedchenko V, Sado Y, Borza DB, Hudson BG (2008) J Biol Chem 283(33): 22737-48
    › Primary publication · 18499662 (PubMed) · PMC2504875 (PubMed Central)
  4. Molecular recognition in the assembly of collagens: terminal noncollagenous domains are key recognition modules in the formation of triple helical protomers. Khoshnoodi J, Cartailler JP, Alvares K, Veis A, Hudson BG (2006) J Biol Chem 281(50): 38117-21
    › Primary publication · 17082192 (PubMed)
  5. Mechanism of chain selection in the assembly of collagen IV: a prominent role for the alpha2 chain. Khoshnoodi J, Sigmundsson K, Cartailler JP, Bondar O, Sundaramoorthy M, Hudson BG (2006) J Biol Chem 281(9): 6058-69
    › Primary publication · 16373348 (PubMed)
  6. Strategies for the use of site-specific recombinases in genome engineering. Jones JR, Shelton KD, Magnuson MA (2005) Methods Mol Med : 245-57
    › Primary publication · 15542911 (PubMed)
  7. Structural and functional characterization of pi bulges and other short intrahelical deformations. Cartailler JP, Luecke H (2004) Structure 12(1): 133-44
    › Primary publication · 14725773 (PubMed)
  8. X-ray crystallographic analysis of lipid-protein interactions in the bacteriorhodopsin purple membrane. Cartailler JP, Luecke H (2003) Annu Rev Biophys Biomol Struct : 285-310
    › Primary publication · 12598369 (PubMed)
  9. Coupling photoisomerization of retinal to directional transport in bacteriorhodopsin. Luecke H, Schobert B, Cartailler JP, Richter HT, Rosengarth A, Needleman R, Lanyi JK (2000) J Mol Biol 300(5): 1237-55
    › Primary publication · 10903866 (PubMed)
  10. Annexins V and XII insert into bilayers at mildly acidic pH and form ion channels. Isas JM, Cartailler JP, Sokolov Y, Patel DR, Langen R, Luecke H, Hall JE, Haigler HT (2000) Biochemistry 39(11): 3015-22
    › Primary publication · 10715122 (PubMed)
  11. Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization. Cartailler JP, Haigler HT, Luecke H (2000) Biochemistry 39(10): 2475-83
    › Primary publication · 10704197 (PubMed)
  12. Structural changes in bacteriorhodopsin during ion transport at 2 angstrom resolution. Luecke H, Schobert B, Richter HT, Cartailler JP, Lanyi JK (1999) Science 286(5438): 255-61
    › Primary publication · 10514362 (PubMed)