Bertha Elias is a Research Instructor at the Vanderbilt University School of Medicine in Nashville, Tennessee. She is a member of the Brooks laboratory in the division of Nephrology.
She received her Ph.D in Zoology from the University of Pune in India. She started her career as a post-doctoral fellow at the Astra Research Centre (a center of excellence of the present AstraZeneca Pharmaceuticals) in Bangalore, India. She stayed on to work as an Associate Scientist with the company till 2001 with the cell biology group. She then did a couple more postdoctoral stints at the Mount Sinai School of Medicine, New York and the University of Tennessee, Memphis.
Her expertise is in using mammalian cell lines to study cell signaling events influenced by extracellular matrix and integrins in kidney development. Regulation of cellular tight and adherans junctions has been her main areas of focus in the recent past. She now focuses on the role of Cyclins G1 and G2 in cell cycle arrest leading to fibrosis. She uses biochemistry, cell biology, molecular biology, confocal microscopy as well as mass spectroscopy in her endeavors to answer interesting questions in her research.
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Key: MeSH Term KeywordAnimals Binding Sites Cell Line Cell Membrane Cell Movement Cell Nucleus Cells, Cultured Chromatography, Paper Claudin-2 Enzyme Activation Epidermal Growth Factor Epithelium Gene Expression Regulation, Enzymologic Guanine Nucleotide Exchange Factors Hydrogen Peroxide Inhibins Integrin beta1 Kidney Tubules, Proximal Mice Mitogen-Activated Protein Kinases Oxidants Oxidative Stress Protein Binding Protein Kinase C Reproducibility of Results RNA, Small Interfering Serine src-Family Kinases Tyrosine Urine